Compile Data Set for Download or QSAR
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Found 85 Enz. Inhib. hit(s) with all data for entry = 50037515
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50169985(4-(2-(4-(benzo[d]thiazol-2(3H)-ylidene(cyano)methy...)
Affinity DataIC50:  41nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50169980(CHEMBL363254 | [3H-Benzothiazol-(2Z)-ylidene]-{2-[...)
Affinity DataIC50:  65nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50169959(2-(benzo[d]thiazol-2(3H)-ylidene)-2-(2-(2-(pyridin...)
Affinity DataIC50:  70nMAssay Description:Inhibition of c-Jun N-Terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50170008(CHEMBL372708 | {2-[2-(4-Amino-phenyl)-ethylamino]-...)
Affinity DataIC50:  80nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50169998(CHEMBL191581 | CHEMBL254651 | [3H-Benzothiazol-(2Z...)
Affinity DataIC50:  80nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50169959(2-(benzo[d]thiazol-2(3H)-ylidene)-2-(2-(2-(pyridin...)
Affinity DataIC50:  120nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50169999(CHEMBL371113 | [3H-Benzothiazol-(2Z)-ylidene]-{2-[...)
Affinity DataIC50:  143nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50170017(CHEMBL189841 | [3H-Benzothiazol-(2Z)-ylidene]-[2-(...)
Affinity DataIC50:  147nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50169959(2-(benzo[d]thiazol-2(3H)-ylidene)-2-(2-(2-(pyridin...)
Affinity DataIC50:  150nMAssay Description:Inhibition of c-Jun N-Terminal kinase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50169959(2-(benzo[d]thiazol-2(3H)-ylidene)-2-(2-(2-(pyridin...)
Affinity DataIC50:  220nMAssay Description:Inhibitory concentration against c-Jun N-Terminal kinase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50169966((2Z)-1,3-benzothiazol-2(3H)-ylidene(2-chloropyrimi...)
Affinity DataIC50:  250nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50170001(CHEMBL364637 | [3H-Benzothiazol-(2Z)-ylidene]-[2-(...)
Affinity DataIC50:  250nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50169965(CHEMBL363253 | [3H-Benzothiazol-(2Z)-ylidene]-{2-[...)
Affinity DataIC50:  273nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50169977(CHEMBL190742 | [3H-Benzothiazol-(2Z)-ylidene]-{2-[...)
Affinity DataIC50:  337nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50169994(CHEMBL189852 | [3H-Benzothiazol-(2Z)-ylidene]-{2-[...)
Affinity DataIC50:  340nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50170014((2Z)-1,3-benzothiazol-2(3H)-ylidene(6-bromo-2-chlo...)
Affinity DataIC50:  350nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50169967(CHEMBL189223 | [3H-Benzothiazol-(2Z)-ylidene]-[2-(...)
Affinity DataIC50:  397nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50169976(CHEMBL191376 | [3H-Benzothiazol-(2Z)-ylidene]-[2-(...)
Affinity DataIC50:  407nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50169978(CHEMBL365963 | [3H-Benzothiazol-(2Z)-ylidene]-[2-(...)
Affinity DataIC50:  458nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50169983(CHEMBL424815 | [3H-Benzothiazol-(2Z)-ylidene]-{2-[...)
Affinity DataIC50:  473nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50169972((2Z)-1,3-benzothiazol-2(3H)-ylidene(2-hydrazinopyr...)
Affinity DataIC50:  500nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50170016(CHEMBL190597 | [3H-Benzothiazol-(2Z)-ylidene]-[2-(...)
Affinity DataIC50:  510nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50169968(CHEMBL370889 | [3H-Benzothiazol-(2Z)-ylidene]-[2-(...)
Affinity DataIC50:  583nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50170006(CHEMBL190250 | [3H-Benzothiazol-(2Z)-ylidene]-{2-[...)
Affinity DataIC50:  600nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50169960(CHEMBL364940 | [3H-Benzothiazol-(2Z)-ylidene]-{2-[...)
Affinity DataIC50:  650nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50170013(CHEMBL191465 | [3H-Benzothiazol-(2Z)-ylidene]-[2-(...)
Affinity DataIC50:  660nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50169979(CHEMBL191021 | [2-(3-Amino-propylamino)-pyrimidin-...)
Affinity DataIC50:  707nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50169963(CHEMBL370899 | [3H-Benzothiazol-(2Z)-ylidene]-[2-(...)
Affinity DataIC50:  760nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50170012(CHEMBL191269 | [3H-Benzothiazol-(2Z)-ylidene]-[2-(...)
Affinity DataIC50:  820nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50169970((2Z)-1,3-benzothiazol-2(3H)-ylidene[2-(methylamino...)
Affinity DataIC50:  950nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50169982((2Z)-(2-chloropyrimidin-4-yl)[5-(trifluoromethyl)-...)
Affinity DataIC50:  993nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50169959(2-(benzo[d]thiazol-2(3H)-ylidene)-2-(2-(2-(pyridin...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of c-SRC tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50169959(2-(benzo[d]thiazol-2(3H)-ylidene)-2-(2-(2-(pyridin...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of RAF proto-oncogene serine/threonine protein kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50169993(CHEMBL425553 | [3H-Benzothiazol-(2Z)-ylidene]-[2-(...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50170011(CHEMBL370960 | [3H-Benzothiazol-(2Z)-ylidene]-{2-[...)
Affinity DataIC50:  1.32E+3nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50170015(CHEMBL191543 | N-[3-(4-{[3H-Benzothiazol-(2Z)-ylid...)
Affinity DataIC50:  1.34E+3nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50169959(2-(benzo[d]thiazol-2(3H)-ylidene)-2-(2-(2-(pyridin...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of CDK2/cyclin AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50169961(CHEMBL363556 | [2-(2-Amino-ethylamino)-pyrimidin-4...)
Affinity DataIC50:  1.49E+3nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50170000(CHEMBL190859 | [3H-Benzothiazol-(2Z)-ylidene]-[2-(...)
Affinity DataIC50:  1.64E+3nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50170005(CHEMBL189421 | [3H-Benzothiazol-(2Z)-ylidene]-{2-[...)
Affinity DataIC50:  1.81E+3nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50169975(CHEMBL188499 | [3H-Benzothiazol-(2Z)-ylidene]-(2-m...)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50169995(2-(2-(4-methoxyphenethylamino)pyrimidin-4-yl)-2-(b...)
Affinity DataIC50:  3.08E+3nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50170009(CHEMBL373086 | [3H-Benzothiazol-(2Z)-ylidene]-{2-[...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50169996(CHEMBL365191 | [3H-Benzothiazol-(2Z)-ylidene]-[2-(...)
Affinity DataIC50:  3.74E+3nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50169959(2-(benzo[d]thiazol-2(3H)-ylidene)-2-(2-(2-(pyridin...)
Affinity DataIC50:  4.80E+3nMAssay Description:Inhibition of MAP kinase p38 alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50170003((2Z)-(2-chloropyrimidin-4-yl)(3-methyl-1,3-benzoth...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50169962(CHEMBL372035 | [3H-Benzothiazol-(2Z)-ylidene]-(2-p...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50169981(CHEMBL425722 | [3H-Benzothiazol-(2Z)-ylidene]-{2-[...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50169973(CHEMBL190591 | [3H-Benzothiazol-(2Z)-ylidene]-(2-d...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50169964(CHEMBL370950 | [3H-Benzothiazol-(2Z)-ylidene]-(2-p...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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