Compile Data Set for Download or QSAR
maximum 50k data
Found 17 Enz. Inhib. hit(s) with all data for entry = 50016947
TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175665((R)-(4-(4-(2,4-dichlorobenzylamino)pyrimidin-2-yl)...)
Affinity DataIC50:  10nMAssay Description:Calcium mobilization mediated by CCR4 receptor in CEMS529 cells by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175665((R)-(4-(4-(2,4-dichlorobenzylamino)pyrimidin-2-yl)...)
Affinity DataIC50:  50nMAssay Description:Displacement of [125I]TARC from human CCR4 receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175661((R)-(4-(4-(2,4-dichlorobenzylamino)pyrimidin-2-yl)...)
Affinity DataIC50:  60nMAssay Description:Displacement of [125I]TARC from human CCR4 receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175671((4-(2-(2,4-dichlorobenzylamino)pyrimidin-4-yl)pipe...)
Affinity DataIC50:  300nMAssay Description:Displacement of [125I]TARC from human CCR4 receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175665((R)-(4-(4-(2,4-dichlorobenzylamino)pyrimidin-2-yl)...)
Affinity DataIC50:  380nMAssay Description:Inhibition of chemotaxis of murine CCR4 transfected L1.2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175664((4-(4-(2,4-dichlorobenzylamino)pyrimidin-2-yl)pipe...)
Affinity DataIC50:  700nMAssay Description:Displacement of [125I]TARC from human CCR4 receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175667((4-(4-(2,4-dichlorobenzylamino)pyrimidin-2-yl)pipe...)
Affinity DataIC50:  800nMAssay Description:Displacement of [125I]TARC from human CCR4 receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175659((S)-(4-(4-(2,4-dichlorobenzylamino)pyrimidin-2-yl)...)
Affinity DataIC50:  1.00E+3nMAssay Description:Displacement of [125I]TARC from human CCR4 receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175673((4-(4-(2,4-dichlorobenzyloxy)pyrimidin-2-yl)pipera...)
Affinity DataIC50:  1.20E+3nMAssay Description:Displacement of [125I]TARC from human CCR4 receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175670(CHEMBL200966 | N-((S)-1-(4-(2,4-dichlorobenzyloxy)...)
Affinity DataIC50:  5.60E+3nMAssay Description:Displacement of [125I]TARC from human CCR4 receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175669((4-(4-(2,4-dichlorobenzylamino)pyrimidin-2-yl)pipe...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]TARC from human CCR4 receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175663((4-(4-(2,4-dichlorobenzyloxy)pyrimidin-2-yl)pipera...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]TARC from human CCR4 receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175662(CHEMBL198077 | N-(3-(4-(2,4-dichlorobenzyloxy)pyri...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]TARC from human CCR4 receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175660(1-(4-(4-(2,4-dichlorobenzyloxy)pyrimidin-2-yl)pipe...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]TARC from human CCR4 receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175672((4-(4-(2,4-dichlorobenzylamino)pyrimidin-2-yl)pipe...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]TARC from human CCR4 receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175666(CHEMBL197654 | N-(2-(4-(2,4-dichlorobenzyloxy)pyri...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]TARC from human CCR4 receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175668(1-(4-(4-(2,4-dichlorobenzyloxy)pyrimidin-2-yl)pipe...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]TARC from human CCR4 receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed