Compile Data Set for Download or QSAR
maximum 50k data
Found 18 Enz. Inhib. hit(s) with all data for entry = 50037662
TargetMu-type opioid receptor(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50176258(3-{(1R,2R)-2-[(dimethylamino)methyl]-1-hydroxycycl...)
Affinity DataIC50:  43nMAssay Description:Inhibition of mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50176263(3-((1R,2R)-2-((dimethylamino)methyl)-1-hydroxycycl...)
Affinity DataIC50:  47nMAssay Description:Inhibition of mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50176259((1R,2R)-2-[(dimethylamino)methyl]-1-(3-methoxyphen...)
Affinity DataIC50:  790nMAssay Description:Inhibition of reuptake of NorepinephrineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50176259((1R,2R)-2-[(dimethylamino)methyl]-1-(3-methoxyphen...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of reuptake of 5HTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50176259((1R,2R)-2-[(dimethylamino)methyl]-1-(3-methoxyphen...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of reuptake of 5HTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50176259((1R,2R)-2-[(dimethylamino)methyl]-1-(3-methoxyphen...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of reuptake of NorepinephrineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50176259((1R,2R)-2-[(dimethylamino)methyl]-1-(3-methoxyphen...)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of reuptake of 5HTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50176259((1R,2R)-2-[(dimethylamino)methyl]-1-(3-methoxyphen...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of reuptake of NorepinephrineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50176259((1R,2R)-2-[(dimethylamino)methyl]-1-(3-methoxyphen...)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of reuptake of NorepinephrineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50176259((1R,2R)-2-[(dimethylamino)methyl]-1-(3-methoxyphen...)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibition of reuptake of 5HTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50176263(3-((1R,2R)-2-((dimethylamino)methyl)-1-hydroxycycl...)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of reuptake of 5HTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50176259((1R,2R)-2-[(dimethylamino)methyl]-1-(3-methoxyphen...)
Affinity DataIC50:  5.30E+3nMAssay Description:Inhibition of mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50176258(3-{(1R,2R)-2-[(dimethylamino)methyl]-1-hydroxycycl...)
Affinity DataIC50:  6.70E+3nMAssay Description:Inhibition of reuptake of NorepinephrineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50176259((1R,2R)-2-[(dimethylamino)methyl]-1-(3-methoxyphen...)
Affinity DataIC50:  7.60E+3nMAssay Description:Inhibition of mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50176258(3-{(1R,2R)-2-[(dimethylamino)methyl]-1-hydroxycycl...)
Affinity DataIC50:  9.90E+3nMAssay Description:Inhibition of reuptake of 5HTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50176259((1R,2R)-2-[(dimethylamino)methyl]-1-(3-methoxyphen...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50176263(3-((1R,2R)-2-((dimethylamino)methyl)-1-hydroxycycl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of reuptake of NorepinephrineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50176259((1R,2R)-2-[(dimethylamino)methyl]-1-(3-methoxyphen...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank