Compile Data Set for Download or QSAR
maximum 50k data
Found 44 Enz. Inhib. hit(s) with all data for entry = 50017148
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50178254(3-(benzo[d][1,3]dioxol-5-yl)-4-(2-(3-(1-methyl-1,2...)
Affinity DataIC50:  0.610nMAssay Description:Inhibition of Integrin alphaV Beta3 receptor by solid-phase receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50178253(3-(benzo[d][1,3]dioxol-5-yl)-4-(2-(3-(5,6,7,8-tetr...)
Affinity DataIC50:  1.18nMAssay Description:Inhibition of Integrin alphaV Beta3 receptor by solid-phase receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50178243(3-(2-(methoxymethyl)thiazol-5-yl)-4-(2-(3-(5,6,7,8...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of Integrin alphaV Beta3 receptor by solid-phase receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50178245(3-(2-cyclopropylthiazol-5-yl)-4-(2-(3-(5,6,7,8-tet...)
Affinity DataIC50:  1.22nMAssay Description:Inhibition of Integrin alphaV Beta3 receptor by solid-phase receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50178242(3-(6-methoxypyridin-3-yl)-4-(2-(3-(5,6,7,8-tetrahy...)
Affinity DataIC50:  1.23nMAssay Description:Inhibition of Integrin alphaV Beta3 receptor by solid-phase receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50178255(3-(6-methoxypyridin-3-yl)-4-(2-(3-(1-methyl-1,2,3,...)
Affinity DataIC50:  1.24nMAssay Description:Inhibition of Integrin alphaV Beta3 receptor by solid-phase receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50178247((S)-3-(benzo[d][1,3]dioxol-5-yl)-4-(2-(4-(4-(pyrro...)
Affinity DataIC50:  1.26nMAssay Description:Inhibition of Integrin alphaV Beta3 receptor by solid-phase receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50178248(3-(3,5-dimethoxyphenyl)-4-(2-(3-(5,6,7,8-tetrahydr...)
Affinity DataIC50:  1.54nMAssay Description:Inhibition of Integrin alphaV Beta3 receptor by solid-phase receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50178250((S)-3-(benzo[d][1,3]dioxol-5-yl)-4-(2-(4-(4-morpho...)
Affinity DataIC50:  1.56nMAssay Description:Inhibition of Integrin alphaV Beta3 receptor by solid-phase receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50178257((S)-3-(benzo[d][1,3]dioxol-5-yl)-4-(2-(4-(4-thiomo...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of Integrin alphaV Beta3 receptor by solid-phase receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50178240(3-(2-phenylthiazol-5-yl)-4-(2-(3-(5,6,7,8-tetrahyd...)
Affinity DataIC50:  1.77nMAssay Description:Inhibition of Integrin alphaV Beta3 receptor by solid-phase receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50178238(3-(2-(4-chlorophenyl)thiazol-5-yl)-4-(2-(3-(5,6,7,...)
Affinity DataIC50:  2.09nMAssay Description:Inhibition of Integrin alphaV Beta3 receptor by solid-phase receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50178241(CHEMBL202054 | b3-(3-fluoro-4-methoxyphenyl)-4-(2-...)
Affinity DataIC50:  2.17nMAssay Description:Inhibition of Integrin alphaV Beta3 receptor by solid-phase receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50178239(3-(3-fluorophenyl)-4-(2-(3-(5,6,7,8-tetrahydro-1,8...)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of Integrin alphaV Beta3 receptor by solid-phase receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50178252(3-(2-methylbenzo[d]thiazol-5-yl)-4-(2-(3-(5,6,7,8-...)
Affinity DataIC50:  2.82nMAssay Description:Inhibition of Integrin alphaV Beta3 receptor by solid-phase receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50178256(3-(6-methoxypyridin-3-yl)-4-(2-(4-(4-(pyrrolidin-1...)
Affinity DataIC50:  3nMAssay Description:Inhibition of Integrin alphaV Beta3 receptor by solid-phase receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50178251(3-(3,4-difluorophenyl)-4-(2-(3-(5,6,7,8-tetrahydro...)
Affinity DataIC50:  3.49nMAssay Description:Inhibition of Integrin alphaV Beta3 receptor by solid-phase receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50178258(3-(6-methoxypyridin-3-yl)-4-(2-(4-(4-morpholinopyr...)
Affinity DataIC50:  3.54nMAssay Description:Inhibition of Integrin alphaV Beta3 receptor by solid-phase receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50178249(3-(6-methoxypyridin-3-yl)-4-(2-(4-(4-thiomorpholin...)
Affinity DataIC50:  3.73nMAssay Description:Inhibition of Integrin alphaV Beta3 receptor by solid-phase receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50178246(3-(4-chlorophenyl)-4-(2-(3-(5,6,7,8-tetrahydro-1,8...)
Affinity DataIC50:  3.81nMAssay Description:Inhibition of Integrin alphaV Beta3 receptor by solid-phase receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50178244(4-(2-(3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)...)
Affinity DataIC50:  11.1nMAssay Description:Inhibition of Integrin alphaV Beta3 receptor by solid-phase receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50178252(3-(2-methylbenzo[d]thiazol-5-yl)-4-(2-(3-(5,6,7,8-...)
Affinity DataIC50:  95.1nMAssay Description:Inhibition of Integrin alphaIIb Beta3 receptor by solid-phase receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50178240(3-(2-phenylthiazol-5-yl)-4-(2-(3-(5,6,7,8-tetrahyd...)
Affinity DataIC50:  252nMAssay Description:Inhibition of Integrin alphaIIb Beta3 receptor by solid-phase receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50178253(3-(benzo[d][1,3]dioxol-5-yl)-4-(2-(3-(5,6,7,8-tetr...)
Affinity DataIC50:  263nMAssay Description:Inhibition of Integrin alphaIIb Beta3 receptor by solid-phase receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50178245(3-(2-cyclopropylthiazol-5-yl)-4-(2-(3-(5,6,7,8-tet...)
Affinity DataIC50:  313nMAssay Description:Inhibition of Integrin alphaV Beta6 receptor in HT29 cells by solid-phase receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50178248(3-(3,5-dimethoxyphenyl)-4-(2-(3-(5,6,7,8-tetrahydr...)
Affinity DataIC50:  350nMAssay Description:Inhibition of Integrin alphaIIb Beta3 receptor by solid-phase receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50178241(CHEMBL202054 | b3-(3-fluoro-4-methoxyphenyl)-4-(2-...)
Affinity DataIC50:  405nMAssay Description:Inhibition of Integrin alphaIIb Beta3 receptor by solid-phase receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50178251(3-(3,4-difluorophenyl)-4-(2-(3-(5,6,7,8-tetrahydro...)
Affinity DataIC50:  484nMAssay Description:Inhibition of Integrin alphaIIb Beta3 receptor by solid-phase receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50178238(3-(2-(4-chlorophenyl)thiazol-5-yl)-4-(2-(3-(5,6,7,...)
Affinity DataIC50:  559nMAssay Description:Inhibition of Integrin alphaIIb Beta3 receptor by solid-phase receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50178239(3-(3-fluorophenyl)-4-(2-(3-(5,6,7,8-tetrahydro-1,8...)
Affinity DataIC50:  559nMAssay Description:Inhibition of Integrin alphaIIb Beta3 receptor by solid-phase receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50178246(3-(4-chlorophenyl)-4-(2-(3-(5,6,7,8-tetrahydro-1,8...)
Affinity DataIC50:  636nMAssay Description:Inhibition of Integrin alphaIIb Beta3 receptor by solid-phase receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50178243(3-(2-(methoxymethyl)thiazol-5-yl)-4-(2-(3-(5,6,7,8...)
Affinity DataIC50:  841nMAssay Description:Inhibition of Integrin alphaV Beta6 receptor in HT29 cells by solid-phase receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50178239(3-(3-fluorophenyl)-4-(2-(3-(5,6,7,8-tetrahydro-1,8...)
Affinity DataIC50:  1.31E+3nMAssay Description:Inhibition of Integrin alphaV Beta6 receptor in HT29 cells by solid-phase receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50178242(3-(6-methoxypyridin-3-yl)-4-(2-(3-(5,6,7,8-tetrahy...)
Affinity DataIC50:  1.32E+3nMAssay Description:Inhibition of Integrin alphaV Beta6 receptor in HT29 cells by solid-phase receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50178248(3-(3,5-dimethoxyphenyl)-4-(2-(3-(5,6,7,8-tetrahydr...)
Affinity DataIC50:  1.74E+3nMAssay Description:Inhibition of Integrin alphaV Beta6 receptor in HT29 cells by solid-phase receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50178244(4-(2-(3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of Integrin alphaIIb Beta3 receptor by solid-phase receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50178251(3-(3,4-difluorophenyl)-4-(2-(3-(5,6,7,8-tetrahydro...)
Affinity DataIC50:  2.12E+3nMAssay Description:Inhibition of Integrin alphaV Beta6 receptor in HT29 cells by solid-phase receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50178253(3-(benzo[d][1,3]dioxol-5-yl)-4-(2-(3-(5,6,7,8-tetr...)
Affinity DataIC50:  2.39E+3nMAssay Description:Inhibition of Integrin alphaV Beta6 receptor in HT29 cells by solid-phase receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50178246(3-(4-chlorophenyl)-4-(2-(3-(5,6,7,8-tetrahydro-1,8...)
Affinity DataIC50:  2.44E+3nMAssay Description:Inhibition of Integrin alphaV Beta6 receptor in HT29 cells by solid-phase receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50178240(3-(2-phenylthiazol-5-yl)-4-(2-(3-(5,6,7,8-tetrahyd...)
Affinity DataIC50:  2.67E+3nMAssay Description:Inhibition of Integrin alphaV Beta6 receptor in HT29 cells by solid-phase receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50178241(CHEMBL202054 | b3-(3-fluoro-4-methoxyphenyl)-4-(2-...)
Affinity DataIC50:  3.26E+3nMAssay Description:Inhibition of Integrin alphaV Beta6 receptor in HT29 cells by solid-phase receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50178238(3-(2-(4-chlorophenyl)thiazol-5-yl)-4-(2-(3-(5,6,7,...)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibition of Integrin alphaV Beta6 receptor in HT29 cells by solid-phase receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50178244(4-(2-(3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)...)
Affinity DataIC50:  5.06E+3nMAssay Description:Inhibition of Integrin alphaV Beta6 receptor in HT29 cells by solid-phase receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50178252(3-(2-methylbenzo[d]thiazol-5-yl)-4-(2-(3-(5,6,7,8-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Integrin alphaV Beta6 receptor in HT29 cells by solid-phase receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed