Compile Data Set for Download or QSAR
maximum 50k data
Found 24 Enz. Inhib. hit(s) with all data for entry = 2803
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bryn Mawr College

LigandPNGBDBM24828(Brassinin derivative, 16 | N-[2-(1H-indol-3-yl)eth...)
Affinity DataKi:  1.16E+4nM ΔG°:  -29.3kJ/molepH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bryn Mawr College

LigandPNGBDBM24825((benzylsulfanyl)-N-(1H-indol-3-ylmethyl)carbothioa...)
Affinity DataKi:  1.32E+4nM ΔG°:  -29.0kJ/molepH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bryn Mawr College

LigandPNGBDBM24827((benzylsulfanyl)-N-[2-(1H-indol-3-yl)ethyl]carboth...)
Affinity DataKi:  1.72E+4nM ΔG°:  -28.3kJ/molepH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bryn Mawr College

LigandPNGBDBM24830(Brassinin derivative, 18 | N-[2-(1H-indol-3-yl)eth...)
Affinity DataKi:  2.05E+4nM ΔG°:  -27.8kJ/molepH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bryn Mawr College

LigandPNGBDBM24829(Brassinin derivative, 17 | N-[2-(1H-indol-3-yl)eth...)
Affinity DataKi:  2.84E+4nM ΔG°:  -27.0kJ/molepH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bryn Mawr College

LigandPNGBDBM24816(Brassinin derivative, 4 | N-[3-(1H-indol-3-yl)prop...)
Affinity DataKi:  3.40E+4nM ΔG°:  -26.5kJ/molepH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bryn Mawr College

LigandPNGBDBM24824(Brassinin derivative, 12 | N-(1H-indol-3-ylmethyl)...)
Affinity DataKi:  3.70E+4nM ΔG°:  -26.3kJ/molepH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bryn Mawr College

LigandPNGBDBM24815(Brassinin derivative, 3 | N-[2-(1-benzothiophen-3-...)
Affinity DataKi:  4.10E+4nM ΔG°:  -26.1kJ/molepH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bryn Mawr College

LigandPNGBDBM24817(Brassinin derivative, 5 | N-(2,3-dihydro-1H-inden-...)
Affinity DataKi:  4.21E+4nM ΔG°:  -26.0kJ/molepH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bryn Mawr College

LigandPNGBDBM24819((methylsulfanyl)-N-(naphthalen-2-ylmethyl)carbothi...)
Affinity DataKi:  4.76E+4nM ΔG°:  -25.7kJ/molepH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bryn Mawr College

LigandPNGBDBM24821((methylsulfanyl)-N-(2-phenylethyl)carbothioamide |...)
Affinity DataKi:  6.24E+4nM ΔG°:  -25.0kJ/molepH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bryn Mawr College

LigandPNGBDBM24820(Brassinin derivative, 8 | N-benzyl(methylsulfanyl)...)
Affinity DataKi:  7.24E+4nM ΔG°:  -24.6kJ/molepH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bryn Mawr College

LigandPNGBDBM24814(Brassinin derivative, 2 | N-[2-(1H-indol-3-yl)ethy...)
Affinity DataKi:  8.25E+4nM ΔG°:  -24.2kJ/molepH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bryn Mawr College

LigandPNGBDBM24813(Brassinin, 1 | N-(1H-indol-3-ylmethyl)(methylsulfa...)
Affinity DataKi:  9.77E+4nM ΔG°:  -23.8kJ/molepH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bryn Mawr College

LigandPNGBDBM24822(Brassinin derivative, 10 | N-[2-(4-fluorophenyl)et...)
Affinity DataKi:  1.49E+5nM ΔG°:  -22.7kJ/molepH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bryn Mawr College

LigandPNGBDBM24818(Brassinin derivative, 6 | N-(adamantan-2-yl)(methy...)
Affinity DataKi:  1.80E+5nM ΔG°:  -22.2kJ/molepH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bryn Mawr College

LigandPNGBDBM24834(N-(1H-indol-3-ylmethyl)propanethioamide | thioamid...)
Affinity DataKi:  2.02E+5nM ΔG°:  -21.9kJ/molepH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bryn Mawr College

LigandPNGBDBM24836(4-(1H-indol-3-ylmethyl)-2-methyl-1,3-thiazole | th...)
Affinity DataKi:  3.29E+5nM ΔG°:  -20.7kJ/molepH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bryn Mawr College

LigandPNGBDBM24832(1-[2-(1H-indol-3-yl)ethyl]-3-methylthiourea | thio...)
Affinity DataKi:  3.42E+5nM ΔG°:  -20.6kJ/molepH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bryn Mawr College

LigandPNGBDBM24826((hexylsulfanyl)-N-(1H-indol-3-ylmethyl)carbothioam...)
Affinity DataKi:  3.64E+5nM ΔG°:  -20.4kJ/molepH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bryn Mawr College

LigandPNGBDBM24823(Brassinin derivative, 11 | N-methyl(methylsulfanyl...)
Affinity DataKi:  1.27E+6nM ΔG°:  -17.2kJ/molepH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bryn Mawr College

LigandPNGBDBM24835(4-(1H-indol-3-ylmethyl)-1,3-thiazole | thiazole, 2...)
Affinity DataKi:  1.29E+6nM ΔG°:  -17.2kJ/molepH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bryn Mawr College

LigandPNGBDBM24833(N-(1H-indol-3-ylmethyl)(methylsulfanyl)formamide |...)
Affinity DatapH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bryn Mawr College

LigandPNGBDBM24831(1-(1H-indol-3-ylmethyl)-3-methylthiourea | thioure...)
Affinity DatapH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed