Compile Data Set for Download or QSAR
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Found 24 Enz. Inhib. hit(s) with all data for entry = 2306
TargetHistone deacetylase 1(Homo sapiens (Human))
Kyushu Institute Of Technology

LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataIC50:  19nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Kyushu Institute Of Technology

LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataIC50:  20nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
Kyushu Institute Of Technology

LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataIC50:  28nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
TargetHistone deacetylase 4(Homo sapiens (Human))
Kyushu Institute Of Technology

LigandPNGBDBM19158((3S,9S,14aR)-9-benzyl-3-(7-bromo-6-oxoheptyl)-6,6-...)
Affinity DataIC50:  59.5nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Kyushu Institute Of Technology

LigandPNGBDBM19162((3S,9S,14aR)-9-benzyl-3-(7-hydroxy-6-oxoheptyl)-6,...)
Affinity DataIC50:  60.4nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Kyushu Institute Of Technology

LigandPNGBDBM19158((3S,9S,14aR)-9-benzyl-3-(7-bromo-6-oxoheptyl)-6,6-...)
Affinity DataIC50:  61.9nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Kyushu Institute Of Technology

LigandPNGBDBM19162((3S,9S,14aR)-9-benzyl-3-(7-hydroxy-6-oxoheptyl)-6,...)
Affinity DataIC50:  223nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Kyushu Institute Of Technology

LigandPNGBDBM19159((3S,9S,14aR)-9-benzyl-6,6-dimethyl-3-(6-oxoheptyl)...)
Affinity DataIC50:  290nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
Kyushu Institute Of Technology

LigandPNGBDBM19158((3S,9S,14aR)-9-benzyl-3-(7-bromo-6-oxoheptyl)-6,6-...)
Affinity DataIC50:  621nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
Kyushu Institute Of Technology

LigandPNGBDBM19162((3S,9S,14aR)-9-benzyl-3-(7-hydroxy-6-oxoheptyl)-6,...)
Affinity DataIC50:  887nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Kyushu Institute Of Technology

LigandPNGBDBM19159((3S,9S,14aR)-9-benzyl-6,6-dimethyl-3-(6-oxoheptyl)...)
Affinity DataIC50:  1.08E+3nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Kyushu Institute Of Technology

LigandPNGBDBM19161(6-[(3S,9S,14aR)-9-benzyl-6,6-dimethyl-1,4,7,10-tet...)
Affinity DataIC50:  1.29E+3nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
Kyushu Institute Of Technology

LigandPNGBDBM19159((3S,9S,14aR)-9-benzyl-6,6-dimethyl-3-(6-oxoheptyl)...)
Affinity DataIC50:  3.70E+3nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Kyushu Institute Of Technology

LigandPNGBDBM19157((3S,9S,14aR)-9-benzyl-6,6-dimethyl-3-[5-(oxiran-2-...)
Affinity DataIC50:  4.05E+3nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Kyushu Institute Of Technology

LigandPNGBDBM19161(6-[(3S,9S,14aR)-9-benzyl-6,6-dimethyl-1,4,7,10-tet...)
Affinity DataIC50:  4.33E+3nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Kyushu Institute Of Technology

LigandPNGBDBM19157((3S,9S,14aR)-9-benzyl-6,6-dimethyl-3-[5-(oxiran-2-...)
Affinity DataIC50:  4.69E+3nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
Kyushu Institute Of Technology

LigandPNGBDBM19161(6-[(3S,9S,14aR)-9-benzyl-6,6-dimethyl-1,4,7,10-tet...)
Affinity DataIC50:  1.41E+4nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
Kyushu Institute Of Technology

LigandPNGBDBM19156((3S,9S,14aR)-9-benzyl-3-(hept-6-en-1-yl)-6,6-dimet...)
Affinity DataIC50: >1.00E+5nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
Kyushu Institute Of Technology

LigandPNGBDBM19157((3S,9S,14aR)-9-benzyl-6,6-dimethyl-3-[5-(oxiran-2-...)
Affinity DataIC50: >1.00E+5nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Kyushu Institute Of Technology

LigandPNGBDBM19156((3S,9S,14aR)-9-benzyl-3-(hept-6-en-1-yl)-6,6-dimet...)
Affinity DataIC50: >1.00E+5nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Kyushu Institute Of Technology

LigandPNGBDBM19160((3S,9S,14aR)-9-benzyl-3-(6,7-dihydroxyheptyl)-6,6-...)
Affinity DataIC50: >1.00E+5nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
Kyushu Institute Of Technology

LigandPNGBDBM19160((3S,9S,14aR)-9-benzyl-3-(6,7-dihydroxyheptyl)-6,6-...)
Affinity DataIC50: >1.00E+5nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Kyushu Institute Of Technology

LigandPNGBDBM19156((3S,9S,14aR)-9-benzyl-3-(hept-6-en-1-yl)-6,6-dimet...)
Affinity DataIC50: >1.00E+5nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Kyushu Institute Of Technology

LigandPNGBDBM19160((3S,9S,14aR)-9-benzyl-3-(6,7-dihydroxyheptyl)-6,6-...)
Affinity DataIC50: >1.00E+5nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed