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PubMed code 16442284

Compile data set for download or QSAR
Found 99 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ghrelin receptor


(Homo sapiens (Human))
BDBM19387
PNG
(2,4-diaminopyrimidine derivative, 8c | 6-[(benzylo...)
Show SMILES CS(=O)(=O)c1ccc(CNc2ccc(cc2)-c2c(N)nc(N)nc2COCc2ccccc2)cc1
Show InChI InChI=1S/C26H27N5O3S/c1-35(32,33)22-13-7-18(8-14-22)15-29-21-11-9-20(10-12-21)24-23(30-26(28)31-25(24)27)17-34-16-19-5-3-2-4-6-19/h2-14,29H,15-17H2,1H3,(H4,27,28,30,31)
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n/an/a 0.300n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by binding assay


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181184
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-((3-...)
Show SMILES CC(C)=CCOCc1nc(N)nc(N)c1-c1ccc(NCc2ccc(cc2)S(C)(=O)=O)cc1
Show InChI InChI=1S/C24H29N5O3S/c1-16(2)12-13-32-15-21-22(23(25)29-24(26)28-21)18-6-8-19(9-7-18)27-14-17-4-10-20(11-5-17)33(3,30)31/h4-12,27H,13-15H2,1-3H3,(H4,25,26,28,29)
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n/an/a 0.400n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by binding assay


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181180
PNG
(CHEMBL377514 | N-(3,5-dimethylbenzyl)-3-(5-(4-(4-(...)
Show SMILES Cc1cc(C)cc(CNC(=O)CCc2nc(N)nc(N)c2-c2ccc(NCc3ccc(cc3)S(C)(=O)=O)cc2)c1
Show InChI InChI=1S/C30H34N6O3S/c1-19-14-20(2)16-22(15-19)18-34-27(37)13-12-26-28(29(31)36-30(32)35-26)23-6-8-24(9-7-23)33-17-21-4-10-25(11-5-21)40(3,38)39/h4-11,14-16,33H,12-13,17-18H2,1-3H3,(H,34,37)(H4,31,32,35,36)
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n/an/a 0.400n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by binding assay


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181214
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-((4-...)
Show SMILES CS(=O)(=O)c1ccc(CNc2ccc(cc2)-c2c(N)nc(N)nc2CNc2ccc(F)cc2)cc1
Show InChI InChI=1S/C25H25FN6O2S/c1-35(33,34)21-12-2-16(3-13-21)14-29-19-8-4-17(5-9-19)23-22(31-25(28)32-24(23)27)15-30-20-10-6-18(26)7-11-20/h2-13,29-30H,14-15H2,1H3,(H4,27,28,31,32)
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n/an/a 1.5n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by binding assay


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181184
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-((3-...)
Show SMILES CC(C)=CCOCc1nc(N)nc(N)c1-c1ccc(NCc2ccc(cc2)S(C)(=O)=O)cc1
Show InChI InChI=1S/C24H29N5O3S/c1-16(2)12-13-32-15-21-22(23(25)29-24(26)28-21)18-6-8-19(9-7-18)27-14-17-4-10-20(11-5-17)33(3,30)31/h4-12,27H,13-15H2,1-3H3,(H4,25,26,28,29)
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n/an/a 1.90n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by FLIPR


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181191
PNG
(CHEMBL205711 | N-(3-chlorobenzyl)-3-(5-(4-(4-(meth...)
Show SMILES CS(=O)(=O)c1ccc(CNc2ccc(cc2)-c2c(N)nc(N)nc2CCC(=O)NCc2cccc(Cl)c2)cc1
Show InChI InChI=1S/C28H29ClN6O3S/c1-39(37,38)23-11-5-18(6-12-23)16-32-22-9-7-20(8-10-22)26-24(34-28(31)35-27(26)30)13-14-25(36)33-17-19-3-2-4-21(29)15-19/h2-12,15,32H,13-14,16-17H2,1H3,(H,33,36)(H4,30,31,34,35)
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n/an/a 2n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by binding assay


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181217
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-((me...)
Show SMILES CN(Cc1nc(N)nc(N)c1-c1ccc(NCc2ccc(cc2)S(C)(=O)=O)cc1)c1ccccc1
Show InChI InChI=1S/C26H28N6O2S/c1-32(21-6-4-3-5-7-21)17-23-24(25(27)31-26(28)30-23)19-10-12-20(13-11-19)29-16-18-8-14-22(15-9-18)35(2,33)34/h3-15,29H,16-17H2,1-2H3,(H4,27,28,30,31)
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n/an/a 2.5n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by binding assay


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181182
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-((fu...)
Show SMILES CS(=O)(=O)c1ccc(CNc2ccc(cc2)-c2c(N)nc(N)nc2COCc2ccco2)cc1
Show InChI InChI=1S/C24H25N5O4S/c1-34(30,31)20-10-4-16(5-11-20)13-27-18-8-6-17(7-9-18)22-21(28-24(26)29-23(22)25)15-32-14-19-3-2-12-33-19/h2-12,27H,13-15H2,1H3,(H4,25,26,28,29)
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n/an/a 2.70n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by binding assay


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181201
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-(iso...)
Show SMILES CC(C)CCOCc1nc(N)nc(N)c1-c1ccc(NCc2ccc(cc2)S(C)(=O)=O)cc1
Show InChI InChI=1S/C24H31N5O3S/c1-16(2)12-13-32-15-21-22(23(25)29-24(26)28-21)18-6-8-19(9-7-18)27-14-17-4-10-20(11-5-17)33(3,30)31/h4-11,16,27H,12-15H2,1-3H3,(H4,25,26,28,29)
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n/an/a 2.80n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by binding assay


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181180
PNG
(CHEMBL377514 | N-(3,5-dimethylbenzyl)-3-(5-(4-(4-(...)
Show SMILES Cc1cc(C)cc(CNC(=O)CCc2nc(N)nc(N)c2-c2ccc(NCc3ccc(cc3)S(C)(=O)=O)cc2)c1
Show InChI InChI=1S/C30H34N6O3S/c1-19-14-20(2)16-22(15-19)18-34-27(37)13-12-26-28(29(31)36-30(32)35-26)23-6-8-24(9-7-23)33-17-21-4-10-25(11-5-21)40(3,38)39/h4-11,14-16,33H,12-13,17-18H2,1-3H3,(H,34,37)(H4,31,32,35,36)
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n/an/a 3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by FLIPR


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181229
PNG
(5-[4-(4-methanesulfonyl-benzylamino)-phenyl]-6-(5-...)
Show SMILES Cc1ccc(COCc2nc(N)nc(N)c2-c2ccc(NCc3ccc(cc3)S(C)(=O)=O)cc2)o1
Show InChI InChI=1S/C25H27N5O4S/c1-16-3-10-20(34-16)14-33-15-22-23(24(26)30-25(27)29-22)18-6-8-19(9-7-18)28-13-17-4-11-21(12-5-17)35(2,31)32/h3-12,28H,13-15H2,1-2H3,(H4,26,27,29,30)
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n/an/a 3.40n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by binding assay


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181225
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-((be...)
Show SMILES CN(Cc1ccccc1)Cc1nc(N)nc(N)c1-c1ccc(NCc2ccc(cc2)S(C)(=O)=O)cc1
Show InChI InChI=1S/C27H30N6O2S/c1-33(17-20-6-4-3-5-7-20)18-24-25(26(28)32-27(29)31-24)21-10-12-22(13-11-21)30-16-19-8-14-23(15-9-19)36(2,34)35/h3-15,30H,16-18H2,1-2H3,(H4,28,29,31,32)
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n/an/a 4n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by binding assay


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181192
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-octy...)
Show SMILES CCCCCCCCc1nc(N)nc(N)c1-c1ccc(NCc2ccc(cc2)S(C)(=O)=O)cc1
Show InChI InChI=1S/C26H35N5O2S/c1-3-4-5-6-7-8-9-23-24(25(27)31-26(28)30-23)20-12-14-21(15-13-20)29-18-19-10-16-22(17-11-19)34(2,32)33/h10-17,29H,3-9,18H2,1-2H3,(H4,27,28,30,31)
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n/an/a 5.20n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by binding assay


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181191
PNG
(CHEMBL205711 | N-(3-chlorobenzyl)-3-(5-(4-(4-(meth...)
Show SMILES CS(=O)(=O)c1ccc(CNc2ccc(cc2)-c2c(N)nc(N)nc2CCC(=O)NCc2cccc(Cl)c2)cc1
Show InChI InChI=1S/C28H29ClN6O3S/c1-39(37,38)23-11-5-18(6-12-23)16-32-22-9-7-20(8-10-22)26-24(34-28(31)35-27(26)30)13-14-25(36)33-17-19-3-2-4-21(29)15-19/h2-12,15,32H,13-14,16-17H2,1H3,(H,33,36)(H4,30,31,34,35)
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by FLIPR


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181204
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-isop...)
Show SMILES CC(C)c1nc(N)nc(N)c1-c1ccc(NCc2ccc(cc2)S(C)(=O)=O)cc1
Show InChI InChI=1S/C21H25N5O2S/c1-13(2)19-18(20(22)26-21(23)25-19)15-6-8-16(9-7-15)24-12-14-4-10-17(11-5-14)29(3,27)28/h4-11,13,24H,12H2,1-3H3,(H4,22,23,25,26)
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n/an/a 5.40n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by binding assay


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181179
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-((ph...)
Show SMILES CS(=O)(=O)c1ccc(CNc2ccc(cc2)-c2c(N)nc(N)nc2CNc2ccccc2)cc1
Show InChI InChI=1S/C25H26N6O2S/c1-34(32,33)21-13-7-17(8-14-21)15-28-20-11-9-18(10-12-20)23-22(30-25(27)31-24(23)26)16-29-19-5-3-2-4-6-19/h2-14,28-29H,15-16H2,1H3,(H4,26,27,30,31)
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by binding assay


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181176
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-hept...)
Show SMILES CCCCCCCc1nc(N)nc(N)c1-c1ccc(NCc2ccc(cc2)S(C)(=O)=O)cc1
Show InChI InChI=1S/C25H33N5O2S/c1-3-4-5-6-7-8-22-23(24(26)30-25(27)29-22)19-11-13-20(14-12-19)28-17-18-9-15-21(16-10-18)33(2,31)32/h9-16,28H,3-8,17H2,1-2H3,(H4,26,27,29,30)
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n/an/a 6n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by binding assay


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181181
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-hexy...)
Show SMILES CCCCCCc1nc(N)nc(N)c1-c1ccc(NCc2ccc(cc2)S(C)(=O)=O)cc1
Show InChI InChI=1S/C24H31N5O2S/c1-3-4-5-6-7-21-22(23(25)29-24(26)28-21)18-10-12-19(13-11-18)27-16-17-8-14-20(15-9-17)32(2,30)31/h8-15,27H,3-7,16H2,1-2H3,(H4,25,26,28,29)
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n/an/a 6n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by binding assay


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181201
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-(iso...)
Show SMILES CC(C)CCOCc1nc(N)nc(N)c1-c1ccc(NCc2ccc(cc2)S(C)(=O)=O)cc1
Show InChI InChI=1S/C24H31N5O3S/c1-16(2)12-13-32-15-21-22(23(25)29-24(26)28-21)18-6-8-19(9-7-18)27-14-17-4-10-20(11-5-17)33(3,30)31/h4-11,16,27H,12-15H2,1-3H3,(H4,25,26,28,29)
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n/an/a 6.80n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by FLIPR


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM19387
PNG
(2,4-diaminopyrimidine derivative, 8c | 6-[(benzylo...)
Show SMILES CS(=O)(=O)c1ccc(CNc2ccc(cc2)-c2c(N)nc(N)nc2COCc2ccccc2)cc1
Show InChI InChI=1S/C26H27N5O3S/c1-35(32,33)22-13-7-18(8-14-22)15-29-21-11-9-20(10-12-21)24-23(30-26(28)31-25(24)27)17-34-16-19-5-3-2-4-6-19/h2-14,29H,15-17H2,1H3,(H4,27,28,30,31)
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n/an/a 7.10n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by FLIPR


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181185
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-(met...)
Show SMILES COCc1nc(N)nc(N)c1-c1ccc(NCc2ccc(cc2)S(C)(=O)=O)cc1
Show InChI InChI=1S/C20H23N5O3S/c1-28-12-17-18(19(21)25-20(22)24-17)14-5-7-15(8-6-14)23-11-13-3-9-16(10-4-13)29(2,26)27/h3-10,23H,11-12H2,1-2H3,(H4,21,22,24,25)
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n/an/a 7.5n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by binding assay


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181217
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-((me...)
Show SMILES CN(Cc1nc(N)nc(N)c1-c1ccc(NCc2ccc(cc2)S(C)(=O)=O)cc1)c1ccccc1
Show InChI InChI=1S/C26H28N6O2S/c1-32(21-6-4-3-5-7-21)17-23-24(25(27)31-26(28)30-23)19-10-12-20(13-11-19)29-16-18-8-14-22(15-9-18)35(2,33)34/h3-15,29H,16-17H2,1-2H3,(H4,27,28,30,31)
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n/an/a 9n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by FLIPR


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181179
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-((ph...)
Show SMILES CS(=O)(=O)c1ccc(CNc2ccc(cc2)-c2c(N)nc(N)nc2CNc2ccccc2)cc1
Show InChI InChI=1S/C25H26N6O2S/c1-34(32,33)21-13-7-17(8-14-21)15-28-20-11-9-18(10-12-20)23-22(30-25(27)31-24(23)26)16-29-19-5-3-2-4-6-19/h2-14,28-29H,15-16H2,1H3,(H4,26,27,30,31)
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n/an/a 9.10n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by FLIPR


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181182
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-((fu...)
Show SMILES CS(=O)(=O)c1ccc(CNc2ccc(cc2)-c2c(N)nc(N)nc2COCc2ccco2)cc1
Show InChI InChI=1S/C24H25N5O4S/c1-34(30,31)20-10-4-16(5-11-20)13-27-18-8-6-17(7-9-18)22-21(28-24(26)29-23(22)25)15-32-14-19-3-2-12-33-19/h2-12,27H,13-15H2,1H3,(H4,25,26,28,29)
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n/an/a 9.60n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by FLIPR


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM19351
PNG
(2,4-diaminopyrimidine-based antagonist, 4c | 6-eth...)
Show SMILES CCc1nc(N)nc(N)c1-c1ccc(NCc2ccc(cc2)S(C)(=O)=O)cc1
Show InChI InChI=1S/C20H23N5O2S/c1-3-17-18(19(21)25-20(22)24-17)14-6-8-15(9-7-14)23-12-13-4-10-16(11-5-13)28(2,26)27/h4-11,23H,3,12H2,1-2H3,(H4,21,22,24,25)
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n/an/a 9.70n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by binding assay


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181229
PNG
(5-[4-(4-methanesulfonyl-benzylamino)-phenyl]-6-(5-...)
Show SMILES Cc1ccc(COCc2nc(N)nc(N)c2-c2ccc(NCc3ccc(cc3)S(C)(=O)=O)cc2)o1
Show InChI InChI=1S/C25H27N5O4S/c1-16-3-10-20(34-16)14-33-15-22-23(24(26)30-25(27)29-22)18-6-8-19(9-7-18)28-13-17-4-11-21(12-5-17)35(2,31)32/h3-12,28H,13-15H2,1-2H3,(H4,26,27,29,30)
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n/an/a 9.70n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by FLIPR


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181210
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-(((4...)
Show SMILES CN(Cc1nc(N)nc(N)c1-c1ccc(NCc2ccc(cc2)S(C)(=O)=O)cc1)c1ccc(F)cc1
Show InChI InChI=1S/C26H27FN6O2S/c1-33(21-11-7-19(27)8-12-21)16-23-24(25(28)32-26(29)31-23)18-5-9-20(10-6-18)30-15-17-3-13-22(14-4-17)36(2,34)35/h3-14,30H,15-16H2,1-2H3,(H4,28,29,31,32)
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n/an/a 10n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by FLIPR


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181193
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-isob...)
Show SMILES CC(C)Cc1nc(N)nc(N)c1-c1ccc(NCc2ccc(cc2)S(C)(=O)=O)cc1
Show InChI InChI=1S/C22H27N5O2S/c1-14(2)12-19-20(21(23)27-22(24)26-19)16-6-8-17(9-7-16)25-13-15-4-10-18(11-5-15)30(3,28)29/h4-11,14,25H,12-13H2,1-3H3,(H4,23,24,26,27)
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n/an/a 10n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by binding assay


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181211
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-tert...)
Show SMILES CC(C)(C)c1nc(N)nc(N)c1-c1ccc(NCc2ccc(cc2)S(C)(=O)=O)cc1
Show InChI InChI=1S/C22H27N5O2S/c1-22(2,3)19-18(20(23)27-21(24)26-19)15-7-9-16(10-8-15)25-13-14-5-11-17(12-6-14)30(4,28)29/h5-12,25H,13H2,1-4H3,(H4,23,24,26,27)
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n/an/a 11n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by FLIPR


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181206
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-buty...)
Show SMILES CCCCc1nc(N)nc(N)c1-c1ccc(NCc2ccc(cc2)S(C)(=O)=O)cc1
Show InChI InChI=1S/C22H27N5O2S/c1-3-4-5-19-20(21(23)27-22(24)26-19)16-8-10-17(11-9-16)25-14-15-6-12-18(13-7-15)30(2,28)29/h6-13,25H,3-5,14H2,1-2H3,(H4,23,24,26,27)
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n/an/a 11n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by binding assay


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181214
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-((4-...)
Show SMILES CS(=O)(=O)c1ccc(CNc2ccc(cc2)-c2c(N)nc(N)nc2CNc2ccc(F)cc2)cc1
Show InChI InChI=1S/C25H25FN6O2S/c1-35(33,34)21-12-2-16(3-13-21)14-29-19-8-4-17(5-9-19)23-22(31-25(28)32-24(23)27)15-30-20-10-6-18(26)7-11-20/h2-13,29-30H,14-15H2,1H3,(H4,27,28,31,32)
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n/an/a 12n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by FLIPR


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181209
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-(ind...)
Show SMILES CS(=O)(=O)c1ccc(CNc2ccc(cc2)-c2c(N)nc(N)nc2CN2CCc3ccccc23)cc1
Show InChI InChI=1S/C27H28N6O2S/c1-36(34,35)22-12-6-18(7-13-22)16-30-21-10-8-20(9-11-21)25-23(31-27(29)32-26(25)28)17-33-15-14-19-4-2-3-5-24(19)33/h2-13,30H,14-17H2,1H3,(H4,28,29,31,32)
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n/an/a 13n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by FLIPR


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181204
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-isop...)
Show SMILES CC(C)c1nc(N)nc(N)c1-c1ccc(NCc2ccc(cc2)S(C)(=O)=O)cc1
Show InChI InChI=1S/C21H25N5O2S/c1-13(2)19-18(20(22)26-21(23)25-19)15-6-8-16(9-7-15)24-12-14-4-10-17(11-5-14)29(3,27)28/h4-11,13,24H,12H2,1-3H3,(H4,22,23,25,26)
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n/an/a 14n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by FLIPR


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181188
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-cycl...)
Show SMILES CS(=O)(=O)c1ccc(CNc2ccc(cc2)-c2c(N)nc(N)nc2C2CCC2)cc1
Show InChI InChI=1S/C22H25N5O2S/c1-30(28,29)18-11-5-14(6-12-18)13-25-17-9-7-15(8-10-17)19-20(16-3-2-4-16)26-22(24)27-21(19)23/h5-12,16,25H,2-4,13H2,1H3,(H4,23,24,26,27)
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n/an/a 14n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by FLIPR


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181196
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-((cy...)
Show SMILES CS(=O)(=O)c1ccc(CNc2ccc(cc2)-c2c(N)nc(N)nc2CNCC2CCCC2)cc1
Show InChI InChI=1S/C25H32N6O2S/c1-34(32,33)21-12-6-18(7-13-21)15-29-20-10-8-19(9-11-20)23-22(30-25(27)31-24(23)26)16-28-14-17-4-2-3-5-17/h6-13,17,28-29H,2-5,14-16H2,1H3,(H4,26,27,30,31)
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n/an/a 16n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by binding assay


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181177
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-pent...)
Show SMILES CCCCCc1nc(N)nc(N)c1-c1ccc(NCc2ccc(cc2)S(C)(=O)=O)cc1
Show InChI InChI=1S/C23H29N5O2S/c1-3-4-5-6-20-21(22(24)28-23(25)27-20)17-9-11-18(12-10-17)26-15-16-7-13-19(14-8-16)31(2,29)30/h7-14,26H,3-6,15H2,1-2H3,(H4,24,25,27,28)
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n/an/a 19n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by binding assay


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181207
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-cycl...)
Show SMILES CS(=O)(=O)c1ccc(CNc2ccc(cc2)-c2c(N)nc(N)nc2C2CC2)cc1
Show InChI InChI=1S/C21H23N5O2S/c1-29(27,28)17-10-2-13(3-11-17)12-24-16-8-6-14(7-9-16)18-19(15-4-5-15)25-21(23)26-20(18)22/h2-3,6-11,15,24H,4-5,12H2,1H3,(H4,22,23,25,26)
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n/an/a 19n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by FLIPR


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181215
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-cycl...)
Show SMILES CS(=O)(=O)c1ccc(CNc2ccc(cc2)-c2c(N)nc(N)nc2C2CCCC2)cc1
Show InChI InChI=1S/C23H27N5O2S/c1-31(29,30)19-12-6-15(7-13-19)14-26-18-10-8-16(9-11-18)20-21(17-4-2-3-5-17)27-23(25)28-22(20)24/h6-13,17,26H,2-5,14H2,1H3,(H4,24,25,27,28)
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n/an/a 21n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by FLIPR


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181206
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-buty...)
Show SMILES CCCCc1nc(N)nc(N)c1-c1ccc(NCc2ccc(cc2)S(C)(=O)=O)cc1
Show InChI InChI=1S/C22H27N5O2S/c1-3-4-5-19-20(21(23)27-22(24)26-19)16-8-10-17(11-9-16)25-14-15-6-12-18(13-7-15)30(2,28)29/h6-13,25H,3-5,14H2,1-2H3,(H4,23,24,26,27)
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n/an/a 32n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by FLIPR


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181203
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-(iso...)
Show SMILES CS(=O)(=O)c1ccc(CNc2ccc(cc2)-c2c(N)nc(N)nc2CN2Cc3ccccc3C2)cc1
Show InChI InChI=1S/C27H28N6O2S/c1-36(34,35)23-12-6-18(7-13-23)14-30-22-10-8-19(9-11-22)25-24(31-27(29)32-26(25)28)17-33-15-20-4-2-3-5-21(20)16-33/h2-13,30H,14-17H2,1H3,(H4,28,29,31,32)
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n/an/a 34n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by FLIPR


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181224
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-cycl...)
Show SMILES CS(=O)(=O)c1ccc(CNc2ccc(cc2)-c2c(N)nc(N)nc2C2CCCCC2)cc1
Show InChI InChI=1S/C24H29N5O2S/c1-32(30,31)20-13-7-16(8-14-20)15-27-19-11-9-17(10-12-19)21-22(18-5-3-2-4-6-18)28-24(26)29-23(21)25/h7-14,18,27H,2-6,15H2,1H3,(H4,25,26,28,29)
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n/an/a 36n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by FLIPR


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM19351
PNG
(2,4-diaminopyrimidine-based antagonist, 4c | 6-eth...)
Show SMILES CCc1nc(N)nc(N)c1-c1ccc(NCc2ccc(cc2)S(C)(=O)=O)cc1
Show InChI InChI=1S/C20H23N5O2S/c1-3-17-18(19(21)25-20(22)24-17)14-6-8-15(9-7-14)23-12-13-4-10-16(11-5-13)28(2,26)27/h4-11,23H,3,12H2,1-2H3,(H4,21,22,24,25)
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n/an/a 37n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by FLIPR


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181198
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-ethy...)
Show SMILES CCc1nc(N)nc(NC)c1-c1ccc(NCc2ccc(cc2)S(C)(=O)=O)cc1
Show InChI InChI=1S/C21H25N5O2S/c1-4-18-19(20(23-2)26-21(22)25-18)15-7-9-16(10-8-15)24-13-14-5-11-17(12-6-14)29(3,27)28/h5-12,24H,4,13H2,1-3H3,(H3,22,23,25,26)
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n/an/a 37n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by binding assay


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181220
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-(2,3...)
Show SMILES CS(=O)(=O)c1ccc(CNc2ccc(cc2)-c2c(N)nc(N)nc2C2Cc3ccccc3O2)cc1
Show InChI InChI=1S/C26H25N5O3S/c1-35(32,33)20-12-6-16(7-13-20)15-29-19-10-8-17(9-11-19)23-24(30-26(28)31-25(23)27)22-14-18-4-2-3-5-21(18)34-22/h2-13,22,29H,14-15H2,1H3,(H4,27,28,30,31)
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n/an/a 38n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by FLIPR


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181223
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-((py...)
Show SMILES CS(=O)(=O)c1ccc(CNc2ccc(cc2)-c2c(N)nc(N)nc2COCc2cccnc2)cc1
Show InChI InChI=1S/C25H26N6O3S/c1-35(32,33)21-10-4-17(5-11-21)14-29-20-8-6-19(7-9-20)23-22(30-25(27)31-24(23)26)16-34-15-18-3-2-12-28-13-18/h2-13,29H,14-16H2,1H3,(H4,26,27,30,31)
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n/an/a 38n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by binding assay


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181176
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-hept...)
Show SMILES CCCCCCCc1nc(N)nc(N)c1-c1ccc(NCc2ccc(cc2)S(C)(=O)=O)cc1
Show InChI InChI=1S/C25H33N5O2S/c1-3-4-5-6-7-8-22-23(24(26)30-25(27)29-22)19-11-13-20(14-12-19)28-17-18-9-15-21(16-10-18)33(2,31)32/h9-16,28H,3-8,17H2,1-2H3,(H4,26,27,29,30)
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n/an/a 38n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by FLIPR


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181193
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-isob...)
Show SMILES CC(C)Cc1nc(N)nc(N)c1-c1ccc(NCc2ccc(cc2)S(C)(=O)=O)cc1
Show InChI InChI=1S/C22H27N5O2S/c1-14(2)12-19-20(21(23)27-22(24)26-19)16-6-8-17(9-7-16)25-13-15-4-10-18(11-5-15)30(3,28)29/h4-11,14,25H,12-13H2,1-3H3,(H4,23,24,26,27)
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n/an/a 40n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by FLIPR


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181227
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-((3,...)
Show SMILES CS(=O)(=O)c1ccc(CNc2ccc(cc2)-c2c(N)nc(N)nc2CN2CCc3ccccc3C2)cc1
Show InChI InChI=1S/C28H30N6O2S/c1-37(35,36)24-12-6-19(7-13-24)16-31-23-10-8-21(9-11-23)26-25(32-28(30)33-27(26)29)18-34-15-14-20-4-2-3-5-22(20)17-34/h2-13,31H,14-18H2,1H3,(H4,29,30,32,33)
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n/an/a 41n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by FLIPR


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181199
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-((be...)
Show SMILES CS(=O)(=O)c1ccc(CNc2ccc(cc2)-c2c(N)nc(N)nc2CNCc2ccccc2)cc1
Show InChI InChI=1S/C26H28N6O2S/c1-35(33,34)22-13-7-19(8-14-22)16-30-21-11-9-20(10-12-21)24-23(31-26(28)32-25(24)27)17-29-15-18-5-3-2-4-6-18/h2-14,29-30H,15-17H2,1H3,(H4,27,28,31,32)
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n/an/a 49n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by FLIPR


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181185
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-(met...)
Show SMILES COCc1nc(N)nc(N)c1-c1ccc(NCc2ccc(cc2)S(C)(=O)=O)cc1
Show InChI InChI=1S/C20H23N5O3S/c1-28-12-17-18(19(21)25-20(22)24-17)14-5-7-15(8-6-14)23-11-13-3-9-16(10-4-13)29(2,26)27/h3-10,23H,11-12H2,1-2H3,(H4,21,22,24,25)
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n/an/a 53n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by FLIPR


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181187
PNG
((S)-5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-...)
Show SMILES CS(=O)(=O)c1ccc(CNc2ccc(cc2)-c2c(N)nc(N)nc2[C@@H]2CCCO2)cc1
Show InChI InChI=1S/C22H25N5O3S/c1-31(28,29)17-10-4-14(5-11-17)13-25-16-8-6-15(7-9-16)19-20(18-3-2-12-30-18)26-22(24)27-21(19)23/h4-11,18,25H,2-3,12-13H2,1H3,(H4,23,24,26,27)/t18-/m0/s1
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n/an/a 54n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by FLIPR


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181192
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-octy...)
Show SMILES CCCCCCCCc1nc(N)nc(N)c1-c1ccc(NCc2ccc(cc2)S(C)(=O)=O)cc1
Show InChI InChI=1S/C26H35N5O2S/c1-3-4-5-6-7-8-9-23-24(25(27)31-26(28)30-23)20-12-14-21(15-13-20)29-18-19-10-16-22(17-11-19)34(2,32)33/h10-17,29H,3-9,18H2,1-2H3,(H4,27,28,30,31)
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n/an/a 57n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by FLIPR


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181231
PNG
((R)-5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-...)
Show SMILES CS(=O)(=O)c1ccc(CNc2ccc(cc2)-c2c(N)nc(N)nc2[C@H]2CCCO2)cc1
Show InChI InChI=1S/C22H25N5O3S/c1-31(28,29)17-10-4-14(5-11-17)13-25-16-8-6-15(7-9-16)19-20(18-3-2-12-30-18)26-22(24)27-21(19)23/h4-11,18,25H,2-3,12-13H2,1H3,(H4,23,24,26,27)/t18-/m1/s1
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n/an/a 57n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by FLIPR


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181219
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-((is...)
Show SMILES CC(C)CCNCc1nc(N)nc(N)c1-c1ccc(NCc2ccc(cc2)S(C)(=O)=O)cc1
Show InChI InChI=1S/C24H32N6O2S/c1-16(2)12-13-27-15-21-22(23(25)30-24(26)29-21)18-6-8-19(9-7-18)28-14-17-4-10-20(11-5-17)33(3,31)32/h4-11,16,27-28H,12-15H2,1-3H3,(H4,25,26,29,30)
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n/an/a 61n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by binding assay


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181181
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-hexy...)
Show SMILES CCCCCCc1nc(N)nc(N)c1-c1ccc(NCc2ccc(cc2)S(C)(=O)=O)cc1
Show InChI InChI=1S/C24H31N5O2S/c1-3-4-5-6-7-21-22(23(25)29-24(26)28-21)18-10-12-19(13-11-18)27-16-17-8-14-20(15-9-17)32(2,30)31/h8-15,27H,3-7,16H2,1-2H3,(H4,25,26,28,29)
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n/an/a 62n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by FLIPR


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181228
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-((cy...)
Show SMILES CS(=O)(=O)c1ccc(CNc2ccc(cc2)-c2c(N)nc(N)nc2CNC2CC2)cc1
Show InChI InChI=1S/C22H26N6O2S/c1-31(29,30)18-10-2-14(3-11-18)12-25-16-6-4-15(5-7-16)20-19(13-26-17-8-9-17)27-22(24)28-21(20)23/h2-7,10-11,17,25-26H,8-9,12-13H2,1H3,(H4,23,24,27,28)
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n/an/a 65n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by binding assay


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181226
PNG
(CHEMBL383766 | exo-5-(4-(4-(methylsulfonyl)benzyla...)
Show SMILES CS(=O)(=O)c1ccc(CNc2ccc(cc2)-c2c(N)nc(N)nc2[C@H]2CC3CC2C=C3)cc1
Show InChI InChI=1S/C25H27N5O2S/c1-33(31,32)20-10-3-15(4-11-20)14-28-19-8-6-17(7-9-19)22-23(29-25(27)30-24(22)26)21-13-16-2-5-18(21)12-16/h2-11,16,18,21,28H,12-14H2,1H3,(H4,26,27,29,30)/t16?,18?,21-/m0/s1
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n/an/a 66n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by FLIPR


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181198
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-ethy...)
Show SMILES CCc1nc(N)nc(NC)c1-c1ccc(NCc2ccc(cc2)S(C)(=O)=O)cc1
Show InChI InChI=1S/C21H25N5O2S/c1-4-18-19(20(23-2)26-21(22)25-18)15-7-9-16(10-8-15)24-13-14-5-11-17(12-6-14)29(3,27)28/h5-12,24H,4,13H2,1-3H3,(H3,22,23,25,26)
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n/an/a 69n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by FLIPR


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181225
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-((be...)
Show SMILES CN(Cc1ccccc1)Cc1nc(N)nc(N)c1-c1ccc(NCc2ccc(cc2)S(C)(=O)=O)cc1
Show InChI InChI=1S/C27H30N6O2S/c1-33(17-20-6-4-3-5-7-20)18-24-25(26(28)32-27(29)31-24)21-10-12-22(13-11-21)30-16-19-8-14-23(15-9-19)36(2,34)35/h3-15,30H,16-18H2,1-2H3,(H4,28,29,31,32)
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n/an/a 69n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by FLIPR


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181202
PNG
(CHEMBL382138 | ethyl 3-(5-(4-(4-(methylsulfonyl)be...)
Show SMILES CCOC(=O)CCc1nc(N)nc(N)c1-c1ccc(NCc2ccc(cc2)S(C)(=O)=O)cc1
Show InChI InChI=1S/C23H27N5O4S/c1-3-32-20(29)13-12-19-21(22(24)28-23(25)27-19)16-6-8-17(9-7-16)26-14-15-4-10-18(11-5-15)33(2,30)31/h4-11,26H,3,12-14H2,1-2H3,(H4,24,25,27,28)
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n/an/a 82n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by FLIPR


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181199
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-((be...)
Show SMILES CS(=O)(=O)c1ccc(CNc2ccc(cc2)-c2c(N)nc(N)nc2CNCc2ccccc2)cc1
Show InChI InChI=1S/C26H28N6O2S/c1-35(33,34)22-13-7-19(8-14-22)16-30-21-11-9-20(10-12-21)24-23(31-26(28)32-25(24)27)17-29-15-18-5-3-2-4-6-18/h2-14,29-30H,15-17H2,1H3,(H4,27,28,31,32)
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n/an/a 96n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by binding assay


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181189
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-((cy...)
Show SMILES CS(=O)(=O)c1ccc(CNc2ccc(cc2)-c2c(N)nc(N)nc2CNC2CCCC2)cc1
Show InChI InChI=1S/C24H30N6O2S/c1-33(31,32)20-12-6-16(7-13-20)14-27-19-10-8-17(9-11-19)22-21(29-24(26)30-23(22)25)15-28-18-4-2-3-5-18/h6-13,18,27-28H,2-5,14-15H2,1H3,(H4,25,26,29,30)
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n/an/a 122n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by binding assay


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181230
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-(bic...)
Show SMILES CS(=O)(=O)c1ccc(CNc2ccc(cc2)-c2c(N)nc(N)nc2C2CC3CCC2C3)cc1
Show InChI InChI=1S/C25H29N5O2S/c1-33(31,32)20-10-3-15(4-11-20)14-28-19-8-6-17(7-9-19)22-23(29-25(27)30-24(22)26)21-13-16-2-5-18(21)12-16/h3-4,6-11,16,18,21,28H,2,5,12-14H2,1H3,(H4,26,27,29,30)
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n/an/a 137n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by FLIPR


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181190
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-ethy...)
Show SMILES CCCNc1nc(N)nc(CC)c1-c1ccc(NCc2ccc(cc2)S(C)(=O)=O)cc1
Show InChI InChI=1S/C23H29N5O2S/c1-4-14-25-22-21(20(5-2)27-23(24)28-22)17-8-10-18(11-9-17)26-15-16-6-12-19(13-7-16)31(3,29)30/h6-13,26H,4-5,14-15H2,1-3H3,(H3,24,25,27,28)
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n/an/a 151n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by binding assay


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181212
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-(2,3...)
Show SMILES CS(=O)(=O)c1ccc(CNc2ccc(cc2)-c2c(N)nc(N)nc2C2COc3ccccc3O2)cc1
Show InChI InChI=1S/C26H25N5O4S/c1-36(32,33)19-12-6-16(7-13-19)14-29-18-10-8-17(9-11-18)23-24(30-26(28)31-25(23)27)22-15-34-20-4-2-3-5-21(20)35-22/h2-13,22,29H,14-15H2,1H3,(H4,27,28,30,31)
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n/an/a 180n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by FLIPR


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181200
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-((di...)
Show SMILES CN(C)Cc1nc(N)nc(N)c1-c1ccc(NCc2ccc(cc2)S(C)(=O)=O)cc1
Show InChI InChI=1S/C21H26N6O2S/c1-27(2)13-18-19(20(22)26-21(23)25-18)15-6-8-16(9-7-15)24-12-14-4-10-17(11-5-14)30(3,28)29/h4-11,24H,12-13H2,1-3H3,(H4,22,23,25,26)
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n/an/a 186n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by binding assay


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181223
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-((py...)
Show SMILES CS(=O)(=O)c1ccc(CNc2ccc(cc2)-c2c(N)nc(N)nc2COCc2cccnc2)cc1
Show InChI InChI=1S/C25H26N6O3S/c1-35(32,33)21-10-4-17(5-11-21)14-29-20-8-6-19(7-9-20)23-22(30-25(27)31-24(23)26)16-34-15-18-3-2-12-28-13-18/h2-13,29H,14-16H2,1H3,(H4,26,27,30,31)
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n/an/a 187n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by FLIPR


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181197
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-ethy...)
Show SMILES CCc1nc(N)nc(N(C)C)c1-c1ccc(NCc2ccc(cc2)S(C)(=O)=O)cc1
Show InChI InChI=1S/C22H27N5O2S/c1-5-19-20(21(27(2)3)26-22(23)25-19)16-8-10-17(11-9-16)24-14-15-6-12-18(13-7-15)30(4,28)29/h6-13,24H,5,14H2,1-4H3,(H2,23,25,26)
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n/an/a 192n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by binding assay


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181186
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-ethy...)
Show SMILES CCc1nc(N)nc(NCC(C)C)c1-c1ccc(NCc2ccc(cc2)S(C)(=O)=O)cc1
Show InChI InChI=1S/C24H31N5O2S/c1-5-21-22(23(27-14-16(2)3)29-24(25)28-21)18-8-10-19(11-9-18)26-15-17-6-12-20(13-7-17)32(4,30)31/h6-13,16,26H,5,14-15H2,1-4H3,(H3,25,27,28,29)
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n/an/a 199n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by binding assay


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181177
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-pent...)
Show SMILES CCCCCc1nc(N)nc(N)c1-c1ccc(NCc2ccc(cc2)S(C)(=O)=O)cc1
Show InChI InChI=1S/C23H29N5O2S/c1-3-4-5-6-20-21(22(24)28-23(25)27-20)17-9-11-18(12-10-17)26-15-16-7-13-19(14-8-16)31(2,29)30/h7-14,26H,3-6,15H2,1-2H3,(H4,24,25,27,28)
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n/an/a 211n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by FLIPR


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181190
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-ethy...)
Show SMILES CCCNc1nc(N)nc(CC)c1-c1ccc(NCc2ccc(cc2)S(C)(=O)=O)cc1
Show InChI InChI=1S/C23H29N5O2S/c1-4-14-25-22-21(20(5-2)27-23(24)28-22)17-8-10-18(11-9-17)26-15-16-6-12-19(13-7-16)31(3,29)30/h6-13,26H,4-5,14-15H2,1-3H3,(H3,24,25,27,28)
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n/an/a 237n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by FLIPR


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181195
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-N4,6-d...)
Show SMILES CCNc1nc(N)nc(CC)c1-c1ccc(NCc2ccc(cc2)S(C)(=O)=O)cc1
Show InChI InChI=1S/C22H27N5O2S/c1-4-19-20(21(24-5-2)27-22(23)26-19)16-8-10-17(11-9-16)25-14-15-6-12-18(13-7-15)30(3,28)29/h6-13,25H,4-5,14H2,1-3H3,(H3,23,24,26,27)
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n/an/a 244n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by binding assay


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181208
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-N4-ben...)
Show SMILES CCc1nc(N)nc(NCc2ccccc2)c1-c1ccc(NCc2ccc(cc2)S(C)(=O)=O)cc1
Show InChI InChI=1S/C27H29N5O2S/c1-3-24-25(26(32-27(28)31-24)30-18-19-7-5-4-6-8-19)21-11-13-22(14-12-21)29-17-20-9-15-23(16-10-20)35(2,33)34/h4-16,29H,3,17-18H2,1-2H3,(H3,28,30,31,32)
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n/an/a 248n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by binding assay


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181221
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-N4-but...)
Show SMILES CCCCNc1nc(N)nc(CC)c1-c1ccc(NCc2ccc(cc2)S(C)(=O)=O)cc1
Show InChI InChI=1S/C24H31N5O2S/c1-4-6-15-26-23-22(21(5-2)28-24(25)29-23)18-9-11-19(12-10-18)27-16-17-7-13-20(14-8-17)32(3,30)31/h7-14,27H,4-6,15-16H2,1-3H3,(H3,25,26,28,29)
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n/an/a 276n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by binding assay


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181205
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-((me...)
Show SMILES CNCc1nc(N)nc(N)c1-c1ccc(NCc2ccc(cc2)S(C)(=O)=O)cc1
Show InChI InChI=1S/C20H24N6O2S/c1-23-12-17-18(19(21)26-20(22)25-17)14-5-7-15(8-6-14)24-11-13-3-9-16(10-4-13)29(2,27)28/h3-10,23-24H,11-12H2,1-2H3,(H4,21,22,25,26)
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n/an/a 279n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by binding assay


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181213
PNG
(CHEMBL383073 | endo-5-(4-(4-(methylsulfonyl)benzyl...)
Show SMILES CS(=O)(=O)c1ccc(CNc2ccc(cc2)-c2c(N)nc(N)nc2[C@@H]2CC3CC2C=C3)cc1
Show InChI InChI=1S/C25H27N5O2S/c1-33(31,32)20-10-3-15(4-11-20)14-28-19-8-6-17(7-9-19)22-23(29-25(27)30-24(22)26)21-13-16-2-5-18(21)12-16/h2-11,16,18,21,28H,12-14H2,1H3,(H4,26,27,29,30)/t16?,18?,21-/m1/s1
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n/an/a 283n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by FLIPR


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181196
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-((cy...)
Show SMILES CS(=O)(=O)c1ccc(CNc2ccc(cc2)-c2c(N)nc(N)nc2CNCC2CCCC2)cc1
Show InChI InChI=1S/C25H32N6O2S/c1-34(32,33)21-12-6-18(7-13-21)15-29-20-10-8-19(9-11-20)23-22(30-25(27)31-24(23)26)16-28-14-17-4-2-3-5-17/h6-13,17,28-29H,2-5,14-16H2,1H3,(H4,26,27,30,31)
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by FLIPR


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181218
PNG
(2-(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-2-a...)
Show SMILES CCc1nc(N)nc(NCCO)c1-c1ccc(NCc2ccc(cc2)S(C)(=O)=O)cc1
Show InChI InChI=1S/C22H27N5O3S/c1-3-19-20(21(24-12-13-28)27-22(23)26-19)16-6-8-17(9-7-16)25-14-15-4-10-18(11-5-15)31(2,29)30/h4-11,25,28H,3,12-14H2,1-2H3,(H3,23,24,26,27)
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n/an/a 354n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by binding assay


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181208
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-N4-ben...)
Show SMILES CCc1nc(N)nc(NCc2ccccc2)c1-c1ccc(NCc2ccc(cc2)S(C)(=O)=O)cc1
Show InChI InChI=1S/C27H29N5O2S/c1-3-24-25(26(32-27(28)31-24)30-18-19-7-5-4-6-8-19)21-11-13-22(14-12-21)29-17-20-9-15-23(16-10-20)35(2,33)34/h4-16,29H,3,17-18H2,1-2H3,(H3,28,30,31,32)
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by FLIPR


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181216
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-N4,N4,...)
Show SMILES CCN(CC)c1nc(N)nc(CC)c1-c1ccc(NCc2ccc(cc2)S(C)(=O)=O)cc1
Show InChI InChI=1S/C24H31N5O2S/c1-5-21-22(23(28-24(25)27-21)29(6-2)7-3)18-10-12-19(13-11-18)26-16-17-8-14-20(15-9-17)32(4,30)31/h8-15,26H,5-7,16H2,1-4H3,(H2,25,27,28)
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n/an/a 380n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by FLIPR


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181216
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-N4,N4,...)
Show SMILES CCN(CC)c1nc(N)nc(CC)c1-c1ccc(NCc2ccc(cc2)S(C)(=O)=O)cc1
Show InChI InChI=1S/C24H31N5O2S/c1-5-21-22(23(28-24(25)27-21)29(6-2)7-3)18-10-12-19(13-11-18)26-16-17-8-14-20(15-9-17)32(4,30)31/h8-15,26H,5-7,16H2,1-4H3,(H2,25,27,28)
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n/an/a 450n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by binding assay


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181183
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-N4-cyc...)
Show SMILES CCc1nc(N)nc(NC2CC2)c1-c1ccc(NCc2ccc(cc2)S(C)(=O)=O)cc1
Show InChI InChI=1S/C23H27N5O2S/c1-3-20-21(22(26-18-10-11-18)28-23(24)27-20)16-6-8-17(9-7-16)25-14-15-4-12-19(13-5-15)31(2,29)30/h4-9,12-13,18,25H,3,10-11,14H2,1-2H3,(H3,24,26,27,28)
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n/an/a 601n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by binding assay


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181178
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-(ami...)
Show SMILES CS(=O)(=O)c1ccc(CNc2ccc(cc2)-c2c(N)nc(N)nc2CN)cc1
Show InChI InChI=1S/C19H22N6O2S/c1-28(26,27)15-8-2-12(3-9-15)11-23-14-6-4-13(5-7-14)17-16(10-20)24-19(22)25-18(17)21/h2-9,23H,10-11,20H2,1H3,(H4,21,22,24,25)
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n/an/a 634n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by binding assay


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181222
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-N4-cyc...)
Show SMILES CCc1nc(N)nc(Nc2ccccc2)c1-c1ccc(NCc2ccc(cc2)S(C)(=O)=O)cc1
Show InChI InChI=1S/C26H27N5O2S/c1-3-23-24(25(31-26(27)30-23)29-21-7-5-4-6-8-21)19-11-13-20(14-12-19)28-17-18-9-15-22(16-10-18)34(2,32)33/h4-16,28H,3,17H2,1-2H3,(H3,27,29,30,31)
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n/an/a 700n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by binding assay


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181221
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-N4-but...)
Show SMILES CCCCNc1nc(N)nc(CC)c1-c1ccc(NCc2ccc(cc2)S(C)(=O)=O)cc1
Show InChI InChI=1S/C24H31N5O2S/c1-4-6-15-26-23-22(21(5-2)28-24(25)29-23)18-9-11-19(12-10-18)27-16-17-7-13-20(14-8-17)32(3,30)31/h7-14,27H,4-6,15-16H2,1-3H3,(H3,25,26,28,29)
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n/an/a 736n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by FLIPR


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181197
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-ethy...)
Show SMILES CCc1nc(N)nc(N(C)C)c1-c1ccc(NCc2ccc(cc2)S(C)(=O)=O)cc1
Show InChI InChI=1S/C22H27N5O2S/c1-5-19-20(21(27(2)3)26-22(23)25-19)16-8-10-17(11-9-16)24-14-15-6-12-18(13-7-15)30(4,28)29/h6-13,24H,5,14H2,1-4H3,(H2,23,25,26)
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n/an/a 772n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by FLIPR


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181228
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-((cy...)
Show SMILES CS(=O)(=O)c1ccc(CNc2ccc(cc2)-c2c(N)nc(N)nc2CNC2CC2)cc1
Show InChI InChI=1S/C22H26N6O2S/c1-31(29,30)18-10-2-14(3-11-18)12-25-16-6-4-15(5-7-16)20-19(13-26-17-8-9-17)27-22(24)28-21(20)23/h2-7,10-11,17,25-26H,8-9,12-13H2,1H3,(H4,23,24,27,28)
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n/an/a 945n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by FLIPR


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181205
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-((me...)
Show SMILES CNCc1nc(N)nc(N)c1-c1ccc(NCc2ccc(cc2)S(C)(=O)=O)cc1
Show InChI InChI=1S/C20H24N6O2S/c1-23-12-17-18(19(21)26-20(22)25-17)14-5-7-15(8-6-14)24-11-13-3-9-16(10-4-13)29(2,27)28/h3-10,23-24H,11-12H2,1-2H3,(H4,21,22,25,26)
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n/an/a 1.38E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by FLIPR


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181219
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-((is...)
Show SMILES CC(C)CCNCc1nc(N)nc(N)c1-c1ccc(NCc2ccc(cc2)S(C)(=O)=O)cc1
Show InChI InChI=1S/C24H32N6O2S/c1-16(2)12-13-27-15-21-22(23(25)30-24(26)29-21)18-6-8-19(9-7-18)28-14-17-4-10-20(11-5-17)33(3,31)32/h4-11,16,27-28H,12-15H2,1-3H3,(H4,25,26,29,30)
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n/an/a 1.42E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by FLIPR


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181186
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-ethy...)
Show SMILES CCc1nc(N)nc(NCC(C)C)c1-c1ccc(NCc2ccc(cc2)S(C)(=O)=O)cc1
Show InChI InChI=1S/C24H31N5O2S/c1-5-21-22(23(27-14-16(2)3)29-24(25)28-21)18-8-10-19(11-9-18)26-15-17-6-12-20(13-7-17)32(4,30)31/h6-13,16,26H,5,14-15H2,1-4H3,(H3,25,27,28,29)
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n/an/a 2.48E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by FLIPR


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181200
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-((di...)
Show SMILES CN(C)Cc1nc(N)nc(N)c1-c1ccc(NCc2ccc(cc2)S(C)(=O)=O)cc1
Show InChI InChI=1S/C21H26N6O2S/c1-27(2)13-18-19(20(22)26-21(23)25-18)15-6-8-16(9-7-15)24-12-14-4-10-17(11-5-14)30(3,28)29/h4-11,24H,12-13H2,1-3H3,(H4,22,23,25,26)
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n/an/a 2.58E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by FLIPR


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181218
PNG
(2-(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-2-a...)
Show SMILES CCc1nc(N)nc(NCCO)c1-c1ccc(NCc2ccc(cc2)S(C)(=O)=O)cc1
Show InChI InChI=1S/C22H27N5O3S/c1-3-19-20(21(24-12-13-28)27-22(23)26-19)16-6-8-17(9-7-16)25-14-15-4-10-18(11-5-15)31(2,29)30/h4-11,25,28H,3,12-14H2,1-2H3,(H3,23,24,26,27)
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n/an/a 3.08E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by FLIPR


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181194
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-4-ethy...)
Show SMILES CCc1nc(N)nc(N2CCOCC2)c1-c1ccc(NCc2ccc(cc2)S(C)(=O)=O)cc1
Show InChI InChI=1S/C24H29N5O3S/c1-3-21-22(23(28-24(25)27-21)29-12-14-32-15-13-29)18-6-8-19(9-7-18)26-16-17-4-10-20(11-5-17)33(2,30)31/h4-11,26H,3,12-16H2,1-2H3,(H2,25,27,28)
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n/an/a 3.25E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by binding assay


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181189
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-((cy...)
Show SMILES CS(=O)(=O)c1ccc(CNc2ccc(cc2)-c2c(N)nc(N)nc2CNC2CCCC2)cc1
Show InChI InChI=1S/C24H30N6O2S/c1-33(31,32)20-12-6-16(7-13-20)14-27-19-10-8-17(9-11-19)22-21(29-24(26)30-23(22)25)15-28-18-4-2-3-5-18/h6-13,18,27-28H,2-5,14-15H2,1H3,(H4,25,26,29,30)
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n/an/a 3.43E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by FLIPR


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181178
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-(ami...)
Show SMILES CS(=O)(=O)c1ccc(CNc2ccc(cc2)-c2c(N)nc(N)nc2CN)cc1
Show InChI InChI=1S/C19H22N6O2S/c1-28(26,27)15-8-2-12(3-9-15)11-23-14-6-4-13(5-7-14)17-16(10-20)24-19(22)25-18(17)21/h2-9,23H,10-11,20H2,1H3,(H4,21,22,24,25)
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n/an/a 7.16E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by FLIPR


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181222
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-N4-cyc...)
Show SMILES CCc1nc(N)nc(Nc2ccccc2)c1-c1ccc(NCc2ccc(cc2)S(C)(=O)=O)cc1
Show InChI InChI=1S/C26H27N5O2S/c1-3-23-24(25(31-26(27)30-23)29-21-7-5-4-6-8-21)19-11-13-20(14-12-19)28-17-18-9-15-22(16-10-18)34(2,32)33/h4-16,28H,3,17H2,1-2H3,(H3,27,29,30,31)
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n/an/a>1.00E+4n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by FLIPR


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181194
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-4-ethy...)
Show SMILES CCc1nc(N)nc(N2CCOCC2)c1-c1ccc(NCc2ccc(cc2)S(C)(=O)=O)cc1
Show InChI InChI=1S/C24H29N5O3S/c1-3-21-22(23(28-24(25)27-21)29-12-14-32-15-13-29)18-6-8-19(9-7-18)26-16-17-4-10-20(11-5-17)33(2,30)31/h4-11,26H,3,12-16H2,1-2H3,(H2,25,27,28)
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n/an/a>1.00E+4n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by FLIPR


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181195
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-N4,6-d...)
Show SMILES CCNc1nc(N)nc(CC)c1-c1ccc(NCc2ccc(cc2)S(C)(=O)=O)cc1
Show InChI InChI=1S/C22H27N5O2S/c1-4-19-20(21(24-5-2)27-22(23)26-19)16-8-10-17(11-9-16)25-14-15-6-12-18(13-7-15)30(3,28)29/h6-13,25H,4-5,14H2,1-3H3,(H3,23,24,26,27)
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n/an/a>1.00E+4n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by FLIPR


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50181183
PNG
(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-N4-cyc...)
Show SMILES CCc1nc(N)nc(NC2CC2)c1-c1ccc(NCc2ccc(cc2)S(C)(=O)=O)cc1
Show InChI InChI=1S/C23H27N5O2S/c1-3-20-21(22(26-18-10-11-18)28-23(24)27-20)16-6-8-17(9-7-16)25-14-15-4-12-19(13-5-15)31(2,29)30/h4-9,12-13,18,25H,3,10-11,14H2,1-2H3,(H3,24,26,27,28)
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n/an/a>1.00E+4n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human GHS receptor by FLIPR


Bioorg Med Chem Lett 16: 1864-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.012
BindingDB Entry DOI: 10.7270/Q2610ZW2
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%