Compile Data Set for Download or QSAR
maximum 50k data
Found 19 Enz. Inhib. hit(s) with all data for entry = 50017437
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50182149(4-((4-bromo-1-methyl-1H-indol-3-yl)methylene)-3-(p...)
Affinity DataIC50:  6nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50182139(4-((4-chloro-1-methyl-1H-indol-3-yl)methylene)-3-(...)
Affinity DataIC50:  9nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50182144(4-((5-chloro-1-methyl-1H-indol-3-yl)methylene)-3-(...)
Affinity DataIC50:  10nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50182152(4-((5-methyl-5H-[1,3]dioxolo[4,5-f]indol-7-yl)meth...)
Affinity DataIC50:  17nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50182141(4-((4-fluoro-1-methyl-1H-indol-3-yl)methylene)-3-(...)
Affinity DataIC50:  17nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50182151(4-((5-fluoro-1-methyl-1H-indol-3-yl)methylene)-3-(...)
Affinity DataIC50:  23nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50182146(4-((4-methoxy-1-methyl-1H-indol-3-yl)methylene)-3-...)
Affinity DataIC50:  26nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50182140(4-((5-methoxy-1-methyl-1H-indol-3-yl)methylene)-3-...)
Affinity DataIC50:  30nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50182142(4-((5-methyl-5H-[1,3]dioxolo[4,5-f]indol-7-yl)meth...)
Affinity DataIC50:  32nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50155151(4-((1-methyl-1H-indol-3-yl)methylene)-3-(pyrazin-2...)
Affinity DataIC50:  37nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50182137(4-((3,5-dimethyl-1H-pyrrol-2-yl)methylene)-3-(pyra...)
Affinity DataIC50:  43nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50182148(4-((4-bromo-1-methyl-1H-indol-3-yl)methylene)-3-(t...)
Affinity DataIC50:  45nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50182136(4-((1-methyl-1H-indol-3-yl)methylene)-3-(thiazol-2...)
Affinity DataIC50:  46nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50182150(4-((5-fluoro-1-methyl-1H-indol-3-yl)methylene)-3-(...)
Affinity DataIC50:  49nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50182138(4-((5-chloro-1-methyl-1H-indol-3-yl)methylene)-3-(...)
Affinity DataIC50:  59nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50182143(4-((3,5-dimethyl-1H-pyrrol-2-yl)methylene)-3-(thia...)
Affinity DataIC50:  63nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50182145(4-((3,5-dimethyl-1H-pyrrol-2-yl)methylene)-3-(fura...)
Affinity DataIC50:  157nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50182147(4-((3,5-dimethyl-1H-pyrrol-2-yl)methylene)-3-pheny...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50182142(4-((5-methyl-5H-[1,3]dioxolo[4,5-f]indol-7-yl)meth...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CDK1/CyclinB1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed