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Found 24 Enz. Inhib. hit(s) with all data for entry = 50017499
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50182922(1-(benzyloxy)-3-(3-(pyridin-4-yl)-1H-indol-6-yl)ur...)
Affinity DataIC50:  76nMAssay Description:Inhibition of IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50182920(1-methyl-1-phenyl-3-(3-(pyridin-4-yl)-1H-indol-6-y...)
Affinity DataIC50:  84nMAssay Description:Inhibition of IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50182927(1-methyl-3-(2-methyl-3-(pyridin-4-yl)-1H-indol-6-y...)
Affinity DataIC50:  128nMAssay Description:Inhibition of IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50182935(CHEMBL379524 | N-(2-methyl-3-(pyridin-4-yl)-1H-ind...)
Affinity DataIC50:  222nMAssay Description:Inhibition of IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50182925(CHEMBL380132 | N-(3-(pyridin-4-yl)-1H-indol-6-yl)b...)
Affinity DataIC50:  364nMAssay Description:Inhibition of IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50182921(6-phenyl-3-(pyridin-4-yl)-1H-indole | CHEMBL207621)
Affinity DataIC50:  456nMAssay Description:Inhibition of IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50182919(CHEMBL208261 | ethyl 3-(pyridin-4-yl)-1H-indole-6-...)
Affinity DataIC50:  586nMAssay Description:Inhibition of IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50133727(1-(3-Cyano-1-methyl-1H-indol-6-yl)-3-phenyl-urea |...)
Affinity DataIC50:  722nMAssay Description:Inhibition of IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50182931(1-methoxy-3-(3-(pyridin-4-yl)-1H-indol-6-yl)urea |...)
Affinity DataIC50:  1.11E+3nMAssay Description:Inhibition of IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50182878(3-(pyridin-4-yl)-1H-indole | CHEMBL380071 | cid_64...)
Affinity DataIC50:  1.15E+3nMAssay Description:Inhibition of IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50182918(1-(benzyloxy)-3-(3-cyano-1-methyl-1H-indol-6-yl)ur...)
Affinity DataIC50:  1.17E+3nMAssay Description:Inhibition of IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50182923(1-(benzyloxy)-3-(3-(pyridin-4-yl)-1H-indol-7-yl)ur...)
Affinity DataIC50:  1.36E+3nMAssay Description:Inhibition of IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50182916(1-methyl-6-({[(methylamino)oxy]carbonyl}amino)-1H-...)
Affinity DataIC50:  4.04E+3nMAssay Description:Inhibition of IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50182934(CHEMBL377529 | N-(3-(pyridin-4-yl)-1H-indol-7-yl)b...)
Affinity DataIC50:  6.21E+3nMAssay Description:Inhibition of IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50182877(1-methyl-1H-indole-3-carbonitrile | CHEMBL205035)
Affinity DataIC50:  7.66E+3nMAssay Description:Inhibition of IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50182928(CHEMBL205236 | N-(3-cyano-1-methyl-1H-indol-6-yl)b...)
Affinity DataIC50:  7.68E+3nMAssay Description:Inhibition of IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50182930(3-(3-cyano-1-methyl-1H-indol-7-yl)-1-methyl-1-phen...)
Affinity DataIC50:  7.85E+3nMAssay Description:Inhibition of IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50182917(3-(3-cyano-1H-indol-6-yl)-1-methyl-1-phenylurea | ...)
Affinity DataIC50:  1.54E+4nMAssay Description:Inhibition of IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50182932(3-(3-cyano-1-methyl-1H-indol-6-yl)-1-methyl-1-phen...)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50182929(1-methyl-1-phenyl-3-(3-(pyridin-4-yl)-1H-indol-7-y...)
Affinity DataIC50:  1.95E+4nMAssay Description:Inhibition of IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50127708((1H)-indole-3-carbonitrile | 1H-Indole-3-carbonitr...)
Affinity DataIC50:  2.09E+4nMAssay Description:Inhibition of IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50182926(CHEMBL378273 | N-(3-cyano-1-methyl-1H-indol-6-yl)(...)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibition of IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50182933(7-(benzo[d]oxazol-2-ylamino)-1-methyl-1H-indole-3-...)
Affinity DataIC50:  5.84E+4nMAssay Description:Inhibition of IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50182924(6-(benzyloxy)-1H-indole-3-carbonitrile | CHEMBL377...)
Affinity DataIC50:  7.18E+4nMAssay Description:Inhibition of IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed