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PubMed code 16640328

Compile data set for download or QSAR
Found 13 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Protein kinase C, eta


(Homo sapiens (Human))
BDBM50185931
PNG
(8-Octyl-benzolactam-V9 | CHEMBL206866)
Show SMILES CCCCCCCCc1cccc2N(C)[C@@H](C(C)C)C(=O)N[C@H](CO)CCc12
Show InChI InChI=1S/C24H40N2O2/c1-5-6-7-8-9-10-12-19-13-11-14-22-21(19)16-15-20(17-27)25-24(28)23(18(2)3)26(22)4/h11,13-14,18,20,23,27H,5-10,12,15-17H2,1-4H3,(H,25,28)/t20-,23-/m0/s1
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144n/an/an/an/an/an/an/an/a



Kyoto University

Curated by ChEMBL


Assay Description
Displacement of [3H]phorbol 12,13-dibutyrate from PKC eta-C1B


J Med Chem 49: 2681-8 (2006)


Article DOI: 10.1021/jm050857c
BindingDB Entry DOI: 10.7270/Q2BR8RSR
More data for this
Ligand-Target Pair
Protein kinase C delta type


(Homo sapiens (Human))
BDBM50185931
PNG
(8-Octyl-benzolactam-V9 | CHEMBL206866)
Show SMILES CCCCCCCCc1cccc2N(C)[C@@H](C(C)C)C(=O)N[C@H](CO)CCc12
Show InChI InChI=1S/C24H40N2O2/c1-5-6-7-8-9-10-12-19-13-11-14-22-21(19)16-15-20(17-27)25-24(28)23(18(2)3)26(22)4/h11,13-14,18,20,23,27H,5-10,12,15-17H2,1-4H3,(H,25,28)/t20-,23-/m0/s1
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216n/an/an/an/an/an/an/an/a



Kyoto University

Curated by ChEMBL


Assay Description
Displacement of [3H]phorbol 12,13-dibutyrate from PKC delta-C1B


J Med Chem 49: 2681-8 (2006)


Article DOI: 10.1021/jm050857c
BindingDB Entry DOI: 10.7270/Q2BR8RSR
More data for this
Ligand-Target Pair
Protein kinase C theta type


(Homo sapiens (Human))
BDBM50185931
PNG
(8-Octyl-benzolactam-V9 | CHEMBL206866)
Show SMILES CCCCCCCCc1cccc2N(C)[C@@H](C(C)C)C(=O)N[C@H](CO)CCc12
Show InChI InChI=1S/C24H40N2O2/c1-5-6-7-8-9-10-12-19-13-11-14-22-21(19)16-15-20(17-27)25-24(28)23(18(2)3)26(22)4/h11,13-14,18,20,23,27H,5-10,12,15-17H2,1-4H3,(H,25,28)/t20-,23-/m0/s1
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290n/an/an/an/an/an/an/an/a



Kyoto University

Curated by ChEMBL


Assay Description
Displacement of [3H]phorbol 12,13-dibutyrate from PKC theta-C1B


J Med Chem 49: 2681-8 (2006)


Article DOI: 10.1021/jm050857c
BindingDB Entry DOI: 10.7270/Q2BR8RSR
More data for this
Ligand-Target Pair
Protein kinase C, epsilon


(Homo sapiens (Human))
BDBM50185931
PNG
(8-Octyl-benzolactam-V9 | CHEMBL206866)
Show SMILES CCCCCCCCc1cccc2N(C)[C@@H](C(C)C)C(=O)N[C@H](CO)CCc12
Show InChI InChI=1S/C24H40N2O2/c1-5-6-7-8-9-10-12-19-13-11-14-22-21(19)16-15-20(17-27)25-24(28)23(18(2)3)26(22)4/h11,13-14,18,20,23,27H,5-10,12,15-17H2,1-4H3,(H,25,28)/t20-,23-/m0/s1
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510n/an/an/an/an/an/an/an/a



Kyoto University

Curated by ChEMBL


Assay Description
Displacement of [3H]phorbol 12,13-dibutyrate from PKC epsilon-C1B


J Med Chem 49: 2681-8 (2006)


Article DOI: 10.1021/jm050857c
BindingDB Entry DOI: 10.7270/Q2BR8RSR
More data for this
Ligand-Target Pair
Protein kinase C, gamma


(Homo sapiens (Human))
BDBM50185931
PNG
(8-Octyl-benzolactam-V9 | CHEMBL206866)
Show SMILES CCCCCCCCc1cccc2N(C)[C@@H](C(C)C)C(=O)N[C@H](CO)CCc12
Show InChI InChI=1S/C24H40N2O2/c1-5-6-7-8-9-10-12-19-13-11-14-22-21(19)16-15-20(17-27)25-24(28)23(18(2)3)26(22)4/h11,13-14,18,20,23,27H,5-10,12,15-17H2,1-4H3,(H,25,28)/t20-,23-/m0/s1
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5.20E+3n/an/an/an/an/an/an/an/a



Kyoto University

Curated by ChEMBL


Assay Description
Displacement of [3H]phorbol 12,13-dibutyrate from PKC gamma-C1B


J Med Chem 49: 2681-8 (2006)


Article DOI: 10.1021/jm050857c
BindingDB Entry DOI: 10.7270/Q2BR8RSR
More data for this
Ligand-Target Pair
Protein kinase C alpha type


(Homo sapiens (Human))
BDBM50185931
PNG
(8-Octyl-benzolactam-V9 | CHEMBL206866)
Show SMILES CCCCCCCCc1cccc2N(C)[C@@H](C(C)C)C(=O)N[C@H](CO)CCc12
Show InChI InChI=1S/C24H40N2O2/c1-5-6-7-8-9-10-12-19-13-11-14-22-21(19)16-15-20(17-27)25-24(28)23(18(2)3)26(22)4/h11,13-14,18,20,23,27H,5-10,12,15-17H2,1-4H3,(H,25,28)/t20-,23-/m0/s1
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>1.00E+4n/an/an/an/an/an/an/an/a



Kyoto University

Curated by ChEMBL


Assay Description
Displacement of [3H]phorbol 12,13-dibutyrate from PKC alpha-C1A


J Med Chem 49: 2681-8 (2006)


Article DOI: 10.1021/jm050857c
BindingDB Entry DOI: 10.7270/Q2BR8RSR
More data for this
Ligand-Target Pair
Protein kinase C alpha type


(Homo sapiens (Human))
BDBM50185931
PNG
(8-Octyl-benzolactam-V9 | CHEMBL206866)
Show SMILES CCCCCCCCc1cccc2N(C)[C@@H](C(C)C)C(=O)N[C@H](CO)CCc12
Show InChI InChI=1S/C24H40N2O2/c1-5-6-7-8-9-10-12-19-13-11-14-22-21(19)16-15-20(17-27)25-24(28)23(18(2)3)26(22)4/h11,13-14,18,20,23,27H,5-10,12,15-17H2,1-4H3,(H,25,28)/t20-,23-/m0/s1
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>1.00E+4n/an/an/an/an/an/an/an/a



Kyoto University

Curated by ChEMBL


Assay Description
Displacement of [3H]phorbol 12,13-dibutyrate from PKC alpha-C1B


J Med Chem 49: 2681-8 (2006)


Article DOI: 10.1021/jm050857c
BindingDB Entry DOI: 10.7270/Q2BR8RSR
More data for this
Ligand-Target Pair
Protein kinase C, gamma


(Homo sapiens (Human))
BDBM50185931
PNG
(8-Octyl-benzolactam-V9 | CHEMBL206866)
Show SMILES CCCCCCCCc1cccc2N(C)[C@@H](C(C)C)C(=O)N[C@H](CO)CCc12
Show InChI InChI=1S/C24H40N2O2/c1-5-6-7-8-9-10-12-19-13-11-14-22-21(19)16-15-20(17-27)25-24(28)23(18(2)3)26(22)4/h11,13-14,18,20,23,27H,5-10,12,15-17H2,1-4H3,(H,25,28)/t20-,23-/m0/s1
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>1.00E+4n/an/an/an/an/an/an/an/a



Kyoto University

Curated by ChEMBL


Assay Description
Displacement of [3H]phorbol 12,13-dibutyrate from PKC gamma-C1A


J Med Chem 49: 2681-8 (2006)


Article DOI: 10.1021/jm050857c
BindingDB Entry DOI: 10.7270/Q2BR8RSR
More data for this
Ligand-Target Pair
Protein kinase C, epsilon


(Homo sapiens (Human))
BDBM50185931
PNG
(8-Octyl-benzolactam-V9 | CHEMBL206866)
Show SMILES CCCCCCCCc1cccc2N(C)[C@@H](C(C)C)C(=O)N[C@H](CO)CCc12
Show InChI InChI=1S/C24H40N2O2/c1-5-6-7-8-9-10-12-19-13-11-14-22-21(19)16-15-20(17-27)25-24(28)23(18(2)3)26(22)4/h11,13-14,18,20,23,27H,5-10,12,15-17H2,1-4H3,(H,25,28)/t20-,23-/m0/s1
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>1.00E+4n/an/an/an/an/an/an/an/a



Kyoto University

Curated by ChEMBL


Assay Description
Displacement of [3H]phorbol 12,13-dibutyrate from PKC epsilon-C1A


J Med Chem 49: 2681-8 (2006)


Article DOI: 10.1021/jm050857c
BindingDB Entry DOI: 10.7270/Q2BR8RSR
More data for this
Ligand-Target Pair
PKC alpha and beta-2


(Homo sapiens (Human))
BDBM50185931
PNG
(8-Octyl-benzolactam-V9 | CHEMBL206866)
Show SMILES CCCCCCCCc1cccc2N(C)[C@@H](C(C)C)C(=O)N[C@H](CO)CCc12
Show InChI InChI=1S/C24H40N2O2/c1-5-6-7-8-9-10-12-19-13-11-14-22-21(19)16-15-20(17-27)25-24(28)23(18(2)3)26(22)4/h11,13-14,18,20,23,27H,5-10,12,15-17H2,1-4H3,(H,25,28)/t20-,23-/m0/s1
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>1.00E+4n/an/an/an/an/an/an/an/a



Kyoto University

Curated by ChEMBL


Assay Description
Displacement of [3H]phorbol 12,13-dibutyrate from PKC beta-C1A


J Med Chem 49: 2681-8 (2006)


Article DOI: 10.1021/jm050857c
BindingDB Entry DOI: 10.7270/Q2BR8RSR
More data for this
Ligand-Target Pair
Protein kinase C, eta


(Homo sapiens (Human))
BDBM50185931
PNG
(8-Octyl-benzolactam-V9 | CHEMBL206866)
Show SMILES CCCCCCCCc1cccc2N(C)[C@@H](C(C)C)C(=O)N[C@H](CO)CCc12
Show InChI InChI=1S/C24H40N2O2/c1-5-6-7-8-9-10-12-19-13-11-14-22-21(19)16-15-20(17-27)25-24(28)23(18(2)3)26(22)4/h11,13-14,18,20,23,27H,5-10,12,15-17H2,1-4H3,(H,25,28)/t20-,23-/m0/s1
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>1.00E+4n/an/an/an/an/an/an/an/a



Kyoto University

Curated by ChEMBL


Assay Description
Displacement of [3H]phorbol 12,13-dibutyrate from PKC eta-C1A


J Med Chem 49: 2681-8 (2006)


Article DOI: 10.1021/jm050857c
BindingDB Entry DOI: 10.7270/Q2BR8RSR
More data for this
Ligand-Target Pair
Protein kinase C delta type


(Homo sapiens (Human))
BDBM50185931
PNG
(8-Octyl-benzolactam-V9 | CHEMBL206866)
Show SMILES CCCCCCCCc1cccc2N(C)[C@@H](C(C)C)C(=O)N[C@H](CO)CCc12
Show InChI InChI=1S/C24H40N2O2/c1-5-6-7-8-9-10-12-19-13-11-14-22-21(19)16-15-20(17-27)25-24(28)23(18(2)3)26(22)4/h11,13-14,18,20,23,27H,5-10,12,15-17H2,1-4H3,(H,25,28)/t20-,23-/m0/s1
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>1.00E+4n/an/an/an/an/an/an/an/a



Kyoto University

Curated by ChEMBL


Assay Description
Displacement of [3H]phorbol 12,13-dibutyrate from PKC delta-C1A


J Med Chem 49: 2681-8 (2006)


Article DOI: 10.1021/jm050857c
BindingDB Entry DOI: 10.7270/Q2BR8RSR
More data for this
Ligand-Target Pair
PKC alpha and beta-2


(Homo sapiens (Human))
BDBM50185931
PNG
(8-Octyl-benzolactam-V9 | CHEMBL206866)
Show SMILES CCCCCCCCc1cccc2N(C)[C@@H](C(C)C)C(=O)N[C@H](CO)CCc12
Show InChI InChI=1S/C24H40N2O2/c1-5-6-7-8-9-10-12-19-13-11-14-22-21(19)16-15-20(17-27)25-24(28)23(18(2)3)26(22)4/h11,13-14,18,20,23,27H,5-10,12,15-17H2,1-4H3,(H,25,28)/t20-,23-/m0/s1
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>1.00E+4n/an/an/an/an/an/an/an/a



Kyoto University

Curated by ChEMBL


Assay Description
Displacement of [3H]phorbol 12,13-dibutyrate from PKC beta-C1B


J Med Chem 49: 2681-8 (2006)


Article DOI: 10.1021/jm050857c
BindingDB Entry DOI: 10.7270/Q2BR8RSR
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%