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PubMed code 16643021

Compile data set for download or QSAR
Found 5 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50259746
PNG
((4-Hydroxyphenyl)ethyl trans-ferulate | CHEMBL4812...)
Show SMILES COc1cc(\C=C\C(=O)OCCc2ccc(O)cc2)ccc1O
Show InChI InChI=1S/C18H18O5/c1-22-17-12-14(4-8-16(17)20)5-9-18(21)23-11-10-13-2-6-15(19)7-3-13/h2-9,12,19-20H,10-11H2,1H3/b9-5+
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Article
PubMed
n/an/a 4.76E+4n/an/an/an/an/an/a



University of Illinois at Chicago

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cells by liquid scintillation counting


J Nat Prod 69: 536-41 (2006)


Article DOI: 10.1021/np050301s
BindingDB Entry DOI: 10.7270/Q2ST7PM1
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50071370
PNG
((3R,8S)-falcarindiol | (3R,8S,)-heptadeca-1,9-dien...)
Show SMILES CCCCCCC\C=C/[C@H](O)C#CC#C[C@H](O)C=C
Show InChI InChI=1S/C17H24O2/c1-3-5-6-7-8-9-10-14-17(19)15-12-11-13-16(18)4-2/h4,10,14,16-19H,2-3,5-9H2,1H3/b14-10-/t16-,17+/m1/s1
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PubMed
n/an/a 1.18E+5n/an/an/an/an/an/a



University of Illinois at Chicago

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cells by liquid scintillation counting


J Nat Prod 69: 536-41 (2006)


Article DOI: 10.1021/np050301s
BindingDB Entry DOI: 10.7270/Q2ST7PM1
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50250299
PNG
((9Z,11S,16R)-dihydroxyoctadeca-9,17-dien-12,14-diy...)
Show SMILES CC(=O)OCCCCCCCC\C=C/[C@H](O)C#CC#C[C@H](O)C=C
Show InChI InChI=1S/C20H28O4/c1-3-19(22)14-11-12-16-20(23)15-10-8-6-4-5-7-9-13-17-24-18(2)21/h3,10,15,19-20,22-23H,1,4-9,13,17H2,2H3/b15-10-/t19-,20+/m1/s1
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PubMed
n/an/a 1.18E+5n/an/an/an/an/an/a



University of Illinois at Chicago

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cells by liquid scintillation counting


J Nat Prod 69: 536-41 (2006)


Article DOI: 10.1021/np050301s
BindingDB Entry DOI: 10.7270/Q2ST7PM1
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50241315
PNG
((Z)-3-butylideneisobenzofuran-1(3H)-one | CHEMBL24...)
Show SMILES CCC\C=C1/OC(=O)c2ccccc12
Show InChI InChI=1S/C12H12O2/c1-2-3-8-11-9-6-4-5-7-10(9)12(13)14-11/h4-8H,2-3H2,1H3/b11-8-
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n/an/a 1.27E+5n/an/an/an/an/an/a



University of Illinois at Chicago

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cells by liquid scintillation counting


J Nat Prod 69: 536-41 (2006)


Article DOI: 10.1021/np050301s
BindingDB Entry DOI: 10.7270/Q2ST7PM1
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50259759
PNG
((S)-8-hydroxy-1-methoxy-, Z-9-heptadecene-4,6-diyn...)
Show SMILES CCCCCCC\C=C/[C@H](O)C#CC#CC(=O)CCOC
Show InChI InChI=1S/C18H26O3/c1-3-4-5-6-7-8-9-12-17(19)13-10-11-14-18(20)15-16-21-2/h9,12,17,19H,3-8,15-16H2,1-2H3/b12-9-/t17-/m0/s1
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PubMed
n/an/a>1.50E+5n/an/an/an/an/an/a



University of Illinois at Chicago

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cells by liquid scintillation counting


J Nat Prod 69: 536-41 (2006)


Article DOI: 10.1021/np050301s
BindingDB Entry DOI: 10.7270/Q2ST7PM1
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%