Compile Data Set for Download or QSAR
maximum 50k data
Found 50 Enz. Inhib. hit(s) with all data for entry = 1812
TargetTryptase beta-2(Homo sapiens (Human))
Celera

LigandPNGBDBM14312(CHEMBL214368 | CRA23 | ethyl N-[(2S)-6-amino-1-(5-...)
Affinity DataKi:  3nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
TargetTryptase beta-2(Homo sapiens (Human))
Celera

LigandPNGBDBM14311(CRA22 | N-[(2S)-6-amino-1-(5-{[4-(2,3-dihydro-1H-i...)
Affinity DataKi:  4nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Celera

LigandPNGBDBM14316((2R)-N-[(2S)-1-(5-{[4-(2,3-dihydro-1H-inden-2-ylca...)
Affinity DataKi:  6nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Celera

LigandPNGBDBM14317(CRA28 | N-[(2S)-1-(5-{[4-(2,3-dihydro-1H-inden-2-y...)
Affinity DataKi:  21nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Celera

LigandPNGBDBM14307((2R)-N-[(1S)-1-{[6-amino-1-(1,3-benzothiazol-2-yl)...)
Affinity DataKi:  23nM ΔG°:  -43.2kJ/molepH: 7.4 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Celera

LigandPNGBDBM14314(CRA25 | prop-2-en-1-yl N-[(2S)-1-(5-{[4-(2,3-dihyd...)
Affinity DataKi:  25nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
TargetSerine protease 1(Bos taurus (bovine))
Celera

LigandPNGBDBM14316((2R)-N-[(2S)-1-(5-{[4-(2,3-dihydro-1H-inden-2-ylca...)
Affinity DataKi:  53nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Celera

LigandPNGBDBM14315(CRA26 | methyl N-[(2S)-1-(5-{[4-(2,3-dihydro-1H-in...)
Affinity DataKi:  130nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Celera

LigandPNGBDBM14312(CHEMBL214368 | CRA23 | ethyl N-[(2S)-6-amino-1-(5-...)
Affinity DataKi:  170nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Celera

LigandPNGBDBM14313(CRA24 | N-[(2S)-1-(5-{[4-(2,3-dihydro-1H-inden-2-y...)
Affinity DataKi:  430nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Celera

LigandPNGBDBM14311(CRA22 | N-[(2S)-6-amino-1-(5-{[4-(2,3-dihydro-1H-i...)
Affinity DataKi:  530nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Celera

LigandPNGBDBM14318(CRA29 | N-[(2S)-4-(azetidin-3-yl)-1-(5-{[4-(2,3-di...)
Affinity DataKi:  590nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Celera

LigandPNGBDBM14297(US10676470, Compound 23 | US11332464, Compound 23 ...)
Affinity DataKi:  690nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Celera

LigandPNGBDBM14314(CRA25 | prop-2-en-1-yl N-[(2S)-1-(5-{[4-(2,3-dihyd...)
Affinity DataKi:  1.60E+3nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Celera

LigandPNGBDBM14300(benzthiazole analog 3 | benzyl N-[(2S,4E)-6-amino-...)
Affinity DataKi:  2.80E+3nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Celera

LigandPNGBDBM14315(CRA26 | methyl N-[(2S)-1-(5-{[4-(2,3-dihydro-1H-in...)
Affinity DataKi:  5.70E+3nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Celera

LigandPNGBDBM14299(benzthiazole analog 2 | benzyl N-[(2S)-1-(1,3-benz...)
Affinity DataKi:  6.90E+3nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Celera

LigandPNGBDBM14297(US10676470, Compound 23 | US11332464, Compound 23 ...)
Affinity DataKi:  7.30E+3nM ΔG°:  -29.0kJ/molepH: 7.4 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Celera

LigandPNGBDBM14317(CRA28 | N-[(2S)-1-(5-{[4-(2,3-dihydro-1H-inden-2-y...)
Affinity DataKi:  7.40E+3nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Celera

LigandPNGBDBM14299(benzthiazole analog 2 | benzyl N-[(2S)-1-(1,3-benz...)
Affinity DataKi:  1.20E+4nM ΔG°:  -27.8kJ/molepH: 7.4 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Celera

LigandPNGBDBM14301(benzthiazole analog 4 | benzyl N-[(2S)-1-(1,3-benz...)
Affinity DataKi:  1.30E+4nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Celera

LigandPNGBDBM14308((2S)-N-[3-(2-amino-1H-1,3-benzodiazol-5-yl)-1-(1,3...)
Affinity DataKi:  1.80E+4nM ΔG°:  -26.8kJ/molepH: 7.4 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Celera

LigandPNGBDBM14300(benzthiazole analog 3 | benzyl N-[(2S,4E)-6-amino-...)
Affinity DataKi:  2.50E+4nM ΔG°:  -26.0kJ/molepH: 7.4 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Celera

LigandPNGBDBM14309(2-Aminobenzimidazole Compound 13 | N-[3-(2-amino-1...)
Affinity DataKi:  3.10E+4nM ΔG°:  -25.5kJ/molepH: 7.4 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Celera

LigandPNGBDBM14301(benzthiazole analog 4 | benzyl N-[(2S)-1-(1,3-benz...)
Affinity DataKi:  4.50E+4nM ΔG°:  -24.6kJ/molepH: 7.4 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Celera

LigandPNGBDBM14313(CRA24 | N-[(2S)-1-(5-{[4-(2,3-dihydro-1H-inden-2-y...)
Affinity DataKi:  7.45E+4nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Celera

LigandPNGBDBM14310(2-Aminobenzimidazole Compound 14 | 3-(2-amino-1H-1...)
Affinity DataKi:  9.40E+4nM ΔG°:  -22.8kJ/molepH: 7.4 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Celera

LigandPNGBDBM7960(1H-1,3-benzodiazol-2-amine | 2-Aminobenzimidazole ...)
Affinity DataKi:  1.10E+5nM ΔG°:  -22.4kJ/molepH: 7.4 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Celera

LigandPNGBDBM14303(benzthiazole analog 6 | benzyl N-[(2S)-3-[(3R)-3-a...)
Affinity DataKi: >1.50E+5nM ΔG°: >-21.6kJ/molepH: 7.4 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Celera

LigandPNGBDBM14303(benzthiazole analog 6 | benzyl N-[(2S)-3-[(3R)-3-a...)
Affinity DataKi: >1.50E+5nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Celera

LigandPNGBDBM14318(CRA29 | N-[(2S)-4-(azetidin-3-yl)-1-(5-{[4-(2,3-di...)
Affinity DataKi:  1.50E+5nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Celera

LigandPNGBDBM14302(benzthiazole analog 5 | benzyl N-[(2S)-3-(6-aminop...)
Affinity DataKi: >1.50E+5nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Celera

LigandPNGBDBM14304(benzthiazole analog 7 | benzyl N-[(2S)-3-(3-amino-...)
Affinity DataKi: >1.50E+5nM ΔG°: >-21.6kJ/molepH: 7.4 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Celera

LigandPNGBDBM14304(benzthiazole analog 7 | benzyl N-[(2S)-3-(3-amino-...)
Affinity DataKi: >1.50E+5nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Celera

LigandPNGBDBM14305(benzthiazole analog 8 | benzyl N-[(2S)-1-(1,3-benz...)
Affinity DataKi: >1.50E+5nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Celera

LigandPNGBDBM14305(benzthiazole analog 8 | benzyl N-[(2S)-1-(1,3-benz...)
Affinity DataKi: >1.50E+5nM ΔG°: >-21.6kJ/molepH: 7.4 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Celera

LigandPNGBDBM14302(benzthiazole analog 5 | benzyl N-[(2S)-3-(6-aminop...)
Affinity DataKi: >1.50E+5nM ΔG°: >-21.6kJ/molepH: 7.4 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Celera

LigandPNGBDBM7960(1H-1,3-benzodiazol-2-amine | 2-Aminobenzimidazole ...)
Affinity DataKi:  2.00E+5nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetTryptase beta-2(Homo sapiens (Human))
Celera

LigandPNGBDBM14324(5,6-dimethyl-1H-1,3-benzodiazol-2-amine | Fragment...)
Affinity DataKi:  2.20E+5nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Celera

LigandPNGBDBM14322(2-Aminoquinoline 1 | 2-aminoquinoline | CHEMBL6123...)
Affinity DataKi:  2.20E+5nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Celera

LigandPNGBDBM14319(1-methyl-1H-1,3-benzodiazol-2-amine | Fragment 16)
Affinity DataKi:  3.70E+5nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Celera

LigandPNGBDBM14320(1-amino-isoquinoline | CHEMBL62083 | Fragment 17 |...)
Affinity DataKi:  3.90E+5nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Celera

LigandPNGBDBM14322(2-Aminoquinoline 1 | 2-aminoquinoline | CHEMBL6123...)
Affinity DataKi:  5.60E+5nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Celera

LigandPNGBDBM14320(1-amino-isoquinoline | CHEMBL62083 | Fragment 17 |...)
Affinity DataKi:  6.00E+5nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Celera

LigandPNGBDBM14324(5,6-dimethyl-1H-1,3-benzodiazol-2-amine | Fragment...)
Affinity DataKi:  1.00E+6nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Celera

LigandPNGBDBM14323(Fragment 20 | quinazoline-2,4-diamine)
Affinity DataKi:  1.20E+6nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Celera

LigandPNGBDBM14319(1-methyl-1H-1,3-benzodiazol-2-amine | Fragment 16)
Affinity DataKi:  1.80E+6nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Celera

LigandPNGBDBM14321(Fragment 18 | quinolin-4-ol)
Affinity DataKi: >2.00E+6nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Celera

LigandPNGBDBM14321(Fragment 18 | quinolin-4-ol)
Affinity DataKi: >2.00E+6nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Celera

LigandPNGBDBM14323(Fragment 20 | quinazoline-2,4-diamine)
Affinity DataKi: >2.00E+6nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed