Compile Data Set for Download or QSAR
maximum 50k data
Found 44 Enz. Inhib. hit(s) with all data for entry = 50017976
TargetFatty acid synthase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50189478(7-chloro-4-hydroxy-3-(2'-methoxy-biphenyl-3-yl)-2-...)
Affinity DataIC50:  19nMAssay Description:Inhibition of human FASMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50189474(7-fluoro-4-hydroxy-6-nitro-3-phenylquinolin-2(1H)-...)
Affinity DataIC50:  50nMAssay Description:Inhibition of rat FASMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50189485(3-biphenyl-3-yl-7-chloro-4-hydroxy-2-oxo-1,2-dihyd...)
Affinity DataIC50:  52nMAssay Description:Inhibition of human FASMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50189457(7-chloro-3-(4'-fluoro-biphenyl-3-yl)-4-hydroxy-2-o...)
Affinity DataIC50:  54nMAssay Description:Inhibition of human FASMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50189473(7-chloro-3-(3',4'-difluoro-biphenyl-3-yl)-4-hydrox...)
Affinity DataIC50:  68nMAssay Description:Inhibition of human FASMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50189472(7-chloro-4-hydroxy-6-nitro-3-phenylquinolin-2(1H)-...)
Affinity DataIC50:  73nMAssay Description:Inhibition of rat FASMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50189486(3-(4-(benzyloxy)phenyl)-7-chloro-4-hydroxy-6-nitro...)
Affinity DataIC50:  86nMAssay Description:Inhibition of rat FASMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50189481(3-(3-(benzo[b]thiophen-3-yl)phenyl)-7-chloro-4-hyd...)
Affinity DataIC50:  101nMAssay Description:Inhibition of human FASMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50189484(3-biphenyl-4-yl-7-chloro-4-hydroxy-6-nitro-1H-quin...)
Affinity DataIC50:  122nMAssay Description:Inhibition of rat FASMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50189480(7-chloro-4-hydroxy-3-(3-naphthalen-2-yl-phenyl)-2-...)
Affinity DataIC50:  127nMAssay Description:Inhibition of human FASMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50189470(7-chloro-3-(3,5-dichlorophenyl)-4-hydroxy-6-nitroq...)
Affinity DataIC50:  134nMAssay Description:Inhibition of rat FASMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50189483(7-chloro-4-hydroxy-2-oxo-3-phenyl-1,2-dihydroquino...)
Affinity DataIC50:  136nMAssay Description:Inhibition of human FASMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50189475(7-chloro-3-(3,5-difluorophenyl)-4-hydroxy-6-nitroq...)
Affinity DataIC50:  172nMAssay Description:Inhibition of rat FASMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50189482(7-chloro-3-(2,4-difluorophenyl)-4-hydroxy-6-nitroq...)
Affinity DataIC50:  173nMAssay Description:Inhibition of rat FASMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50189488(7-chloro-4-hydroxy-2-oxo-3-(3-(pyridin-3-yl)phenyl...)
Affinity DataIC50:  194nMAssay Description:Inhibition of human FASMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50189472(7-chloro-4-hydroxy-6-nitro-3-phenylquinolin-2(1H)-...)
Affinity DataIC50:  207nMAssay Description:Inhibition of human FASMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50189459(8-chloro-4-hydroxy-2-oxo-3-phenyl-1,2-dihydroquino...)
Affinity DataIC50:  402nMAssay Description:Inhibition of human FASMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50189460(7-chloro-3-(2,4-dichlorophenyl)-4-hydroxy-6-nitroq...)
Affinity DataIC50:  443nMAssay Description:Inhibition of rat FASMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50189455(4-hydroxy-6-nitro-3-phenylquinolin-2(1H)-one | CHE...)
Affinity DataIC50:  550nMAssay Description:Inhibition of rat FASMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50189466(7-chloro-4-hydroxy-6-nitro-3-(thiophen-2-yl)quinol...)
Affinity DataIC50:  700nMAssay Description:Inhibition of rat FASMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50189456(7-chloro-3-(3',5'-difluoro-biphenyl-3-yl)-4-hydrox...)
Affinity DataIC50:  728nMAssay Description:Inhibition of human FASMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50189463(7-chloro-4-hydroxy-3-(3-(1-methyl-1H-pyrazol-4-yl)...)
Affinity DataIC50:  734nMAssay Description:Inhibition of human FASMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50189491(4-hydroxy-2-oxo-3-phenyl-1,2-dihydroquinoline-6-ca...)
Affinity DataIC50:  1.29E+3nMAssay Description:Inhibition of human FASMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50189455(4-hydroxy-6-nitro-3-phenylquinolin-2(1H)-one | CHE...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of human FASMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50189458(7-chloro-4-hydroxy-6-nitro-3-(1H-tetrazol-5-yl)qui...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of rat FASMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50189477(4-hydroxy-8-nitro-3-phenylquinolin-2(1H)-one | CHE...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of rat FASMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50189492(7-chloro-4-hydroxy-3-(3-methylisoxazol-5-yl)-6-nit...)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of rat FASMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50189476(7-chloro-4-hydroxy-3-(3-(methylsulfonyl)phenyl)-2-...)
Affinity DataIC50:  4.16E+3nMAssay Description:Inhibition of human FASMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50189489(7-chloro-4-hydroxy-3-(naphthalen-2-yl)-6-nitroquin...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of rat FASMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50001260(3-phenyl-4-hydroxyquinolin-2(1H)-one | 4-Hydroxy-3...)
Affinity DataIC50: >1.50E+4nMAssay Description:Inhibition of rat FASMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50189487(4-hydroxy-3-phenyl-6-(trifluoromethylsulfonyl)quin...)
Affinity DataIC50: >1.50E+4nMAssay Description:Inhibition of rat FASMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50189469(4-hydroxy-2-oxo-3-phenyl-1,2-dihydroquinoline-6-ca...)
Affinity DataIC50: >1.50E+4nMAssay Description:Inhibition of rat FASMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50189468(4-hydroxy-3-phenyl-6-(trifluoromethyl)quinolin-2(1...)
Affinity DataIC50: >1.50E+4nMAssay Description:Inhibition of rat FASMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50189467(4-hydroxy-6-nitroquinolin-2(1H)-one | CHEMBL377915)
Affinity DataIC50: >1.50E+4nMAssay Description:Inhibition of rat FASMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50189461(4-hydroxy-6-(methylsulfonyl)-3-phenylquinolin-2(1H...)
Affinity DataIC50: >1.50E+4nMAssay Description:Inhibition of rat FASMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50189468(4-hydroxy-3-phenyl-6-(trifluoromethyl)quinolin-2(1...)
Affinity DataIC50: >1.50E+4nMAssay Description:Inhibition of human FASMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50189490(4,7-dichloro-2-oxo-3-phenyl-1,2-dihydroquinoline-6...)
Affinity DataIC50: >1.50E+4nMAssay Description:Inhibition of human FASMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50189461(4-hydroxy-6-(methylsulfonyl)-3-phenylquinolin-2(1H...)
Affinity DataIC50: >1.50E+4nMAssay Description:Inhibition of human FASMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50189487(4-hydroxy-3-phenyl-6-(trifluoromethylsulfonyl)quin...)
Affinity DataIC50: >1.50E+4nMAssay Description:Inhibition of human FASMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50189465(4-bromo-7-chloro-2-oxo-3-phenyl-1,2-dihydroquinoli...)
Affinity DataIC50: >1.50E+4nMAssay Description:Inhibition of human FASMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50189464(4-amino-7-chloro-2-oxo-3-phenyl-1,2-dihydroquinoli...)
Affinity DataIC50: >1.50E+4nMAssay Description:Inhibition of human FASMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50189479(4-(4-methoxybenzylamino)-7-chloro-2-oxo-3-phenyl-1...)
Affinity DataIC50: >1.50E+4nMAssay Description:Inhibition of human FASMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50189462(4-(benzylamino)-7-chloro-2-oxo-3-phenyl-1,2-dihydr...)
Affinity DataIC50: >1.50E+4nMAssay Description:Inhibition of human FASMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50189471(7-chloro-2-oxo-3-phenyl-1,2-dihydroquinoline-4,6-d...)
Affinity DataIC50: >1.50E+4nMAssay Description:Inhibition of human FASMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed