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PubMed code 16824756

Compile data set for download or QSAR
Found 24 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50190964
PNG
(6-(3-chloro-4-methoxyphenethyl)-6-cyclopentyl-4-hy...)
Show SMILES COc1ccc(CCC2(CC(=O)C(Sc3nncn3C)C(=O)O2)C2CCCC2)cc1Cl
Show InChI InChI=1S/C22H26ClN3O4S/c1-26-13-24-25-21(26)31-19-17(27)12-22(30-20(19)28,15-5-3-4-6-15)10-9-14-7-8-18(29-2)16(23)11-14/h7-8,11,13,15,19H,3-6,9-10,12H2,1-2H3
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n/an/a 38n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory activity against HCV 1b BK NS5B deltaC21 RNA polymerase


Bioorg Med Chem Lett 16: 4834-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.06.065
BindingDB Entry DOI: 10.7270/Q2S46RK4
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50190967
PNG
(6-(3-chloro-4-methoxyphenethyl)-6-cyclopentyl-4-hy...)
Show SMILES COc1ccc(CCC2(CC(=O)C(Sc3ccc(O)cc3)C(=O)O2)C2CCCC2)cc1Cl
Show InChI InChI=1S/C25H27ClO5S/c1-30-22-11-6-16(14-20(22)26)12-13-25(17-4-2-3-5-17)15-21(28)23(24(29)31-25)32-19-9-7-18(27)8-10-19/h6-11,14,17,23,27H,2-5,12-13,15H2,1H3
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n/an/a 130n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory activity against HCV 1b BK NS5B deltaC21 RNA polymerase


Bioorg Med Chem Lett 16: 4834-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.06.065
BindingDB Entry DOI: 10.7270/Q2S46RK4
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50190951
PNG
(6-(3-chloro-4-methoxyphenethyl)-6-cyclopentyl-4-hy...)
Show SMILES COc1ccc(CCC2(CC(=O)C(Sc3nccn3C)C(=O)O2)C2CCCC2)cc1Cl
Show InChI InChI=1S/C23H27ClN2O4S/c1-26-12-11-25-22(26)31-20-18(27)14-23(30-21(20)28,16-5-3-4-6-16)10-9-15-7-8-19(29-2)17(24)13-15/h7-8,11-13,16,20H,3-6,9-10,14H2,1-2H3
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n/an/a 140n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory activity against HCV 1b BK NS5B deltaC21 RNA polymerase


Bioorg Med Chem Lett 16: 4834-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.06.065
BindingDB Entry DOI: 10.7270/Q2S46RK4
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50190956
PNG
(6-(3-chloro-4-methoxyphenethyl)-6-cyclopentyl-4-hy...)
Show SMILES COc1ccc(CCC2(CC(=O)C(Sc3nnnn3C)C(=O)O2)C2CCCC2)cc1Cl
Show InChI InChI=1S/C21H25ClN4O4S/c1-26-20(23-24-25-26)31-18-16(27)12-21(30-19(18)28,14-5-3-4-6-14)10-9-13-7-8-17(29-2)15(22)11-13/h7-8,11,14,18H,3-6,9-10,12H2,1-2H3
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n/an/a 280n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory activity against HCV 1b BK NS5B deltaC21 RNA polymerase


Bioorg Med Chem Lett 16: 4834-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.06.065
BindingDB Entry DOI: 10.7270/Q2S46RK4
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50190968
PNG
(6-(3-fluoro-4-isopropoxyphenethyl)-6-cyclopentyl-d...)
Show SMILES CC(C)Oc1ccc(CCC2(CC(=O)CC(=O)O2)C2CCCC2)cc1F
Show InChI InChI=1S/C21H27FO4/c1-14(2)25-19-8-7-15(11-18(19)22)9-10-21(16-5-3-4-6-16)13-17(23)12-20(24)26-21/h7-8,11,14,16H,3-6,9-10,12-13H2,1-2H3
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n/an/a 530n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory activity against HCV 1b BK NS5B deltaC21 RNA polymerase


Bioorg Med Chem Lett 16: 4834-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.06.065
BindingDB Entry DOI: 10.7270/Q2S46RK4
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50190969
PNG
(6-(3-chloro-4-methoxyphenethyl)-6-cyclopentyl-4-hy...)
Show SMILES COc1ccc(CCC2(CC(=O)C(Sc3ccccc3)C(=O)O2)C2CCCC2)cc1Cl
Show InChI InChI=1S/C25H27ClO4S/c1-29-22-12-11-17(15-20(22)26)13-14-25(18-7-5-6-8-18)16-21(27)23(24(28)30-25)31-19-9-3-2-4-10-19/h2-4,9-12,15,18,23H,5-8,13-14,16H2,1H3
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n/an/a 560n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory activity against HCV 1b BK NS5B deltaC21 RNA polymerase


Bioorg Med Chem Lett 16: 4834-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.06.065
BindingDB Entry DOI: 10.7270/Q2S46RK4
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50190952
PNG
(6-(4-ethoxy-3-fluorophenethyl)-6-cyclopentyl-dihyd...)
Show SMILES CCOc1ccc(CCC2(CC(=O)CC(=O)O2)C2CCCC2)cc1F
Show InChI InChI=1S/C20H25FO4/c1-2-24-18-8-7-14(11-17(18)21)9-10-20(15-5-3-4-6-15)13-16(22)12-19(23)25-20/h7-8,11,15H,2-6,9-10,12-13H2,1H3
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n/an/a 790n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory activity against HCV 1b BK NS5B deltaC21 RNA polymerase


Bioorg Med Chem Lett 16: 4834-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.06.065
BindingDB Entry DOI: 10.7270/Q2S46RK4
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50190957
PNG
(6-(3-fluoro-4-methoxyphenethyl)-6-cyclopentyl-dihy...)
Show SMILES COc1ccc(CCC2(CC(=O)CC(=O)O2)C2CCCC2)cc1F
Show InChI InChI=1S/C19H23FO4/c1-23-17-7-6-13(10-16(17)20)8-9-19(14-4-2-3-5-14)12-15(21)11-18(22)24-19/h6-7,10,14H,2-5,8-9,11-12H2,1H3
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n/an/a 890n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory activity against HCV 1b BK NS5B deltaC21 RNA polymerase


Bioorg Med Chem Lett 16: 4834-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.06.065
BindingDB Entry DOI: 10.7270/Q2S46RK4
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50078109
PNG
(3-(4-Amino-2-tert-butyl-5-methyl-phenylsulfanyl)-6...)
Show SMILES Cc1cc(SC2C(=O)CC(CCc3ccc(O)cc3)(OC2=O)C2CCCC2)c(cc1N)C(C)(C)C
Show InChI InChI=1S/C29H37NO4S/c1-18-15-25(22(16-23(18)30)28(2,3)4)35-26-24(32)17-29(34-27(26)33,20-7-5-6-8-20)14-13-19-9-11-21(31)12-10-19/h9-12,15-16,20,26,31H,5-8,13-14,17,30H2,1-4H3
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n/an/a 930n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory activity against HCV 1b BK NS5B deltaC21 RNA polymerase


Bioorg Med Chem Lett 16: 4834-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.06.065
BindingDB Entry DOI: 10.7270/Q2S46RK4
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50190963
PNG
(6-(3-chloro-4-methoxyphenethyl)-6-cyclopentyl-dihy...)
Show SMILES COc1ccc(CCC2(CC(=O)CC(=O)O2)C2CCCC2)cc1Cl
Show InChI InChI=1S/C19H23ClO4/c1-23-17-7-6-13(10-16(17)20)8-9-19(14-4-2-3-5-14)12-15(21)11-18(22)24-19/h6-7,10,14H,2-5,8-9,11-12H2,1H3
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n/an/a 1.00E+3n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory activity against HCV 1b BK NS5B deltaC21 RNA polymerase


Bioorg Med Chem Lett 16: 4834-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.06.065
BindingDB Entry DOI: 10.7270/Q2S46RK4
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50190966
PNG
(6-(4-isopropoxyphenethyl)-6-cyclopentyl-dihydro-3H...)
Show SMILES CC(C)Oc1ccc(CCC2(CC(=O)CC(=O)O2)C2CCCC2)cc1
Show InChI InChI=1S/C21H28O4/c1-15(2)24-19-9-7-16(8-10-19)11-12-21(17-5-3-4-6-17)14-18(22)13-20(23)25-21/h7-10,15,17H,3-6,11-14H2,1-2H3
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n/an/a 1.70E+3n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory activity against HCV 1b BK NS5B deltaC21 RNA polymerase


Bioorg Med Chem Lett 16: 4834-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.06.065
BindingDB Entry DOI: 10.7270/Q2S46RK4
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50190953
PNG
(6-(3-isopropylphenethyl)-6-cyclopentyl-dihydro-3H-...)
Show SMILES CC(C)c1cccc(CCC2(CC(=O)CC(=O)O2)C2CCCC2)c1
Show InChI InChI=1S/C21H28O3/c1-15(2)17-7-5-6-16(12-17)10-11-21(18-8-3-4-9-18)14-19(22)13-20(23)24-21/h5-7,12,15,18H,3-4,8-11,13-14H2,1-2H3
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n/an/a 1.80E+3n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory activity against HCV 1b BK NS5B deltaC21 RNA polymerase


Bioorg Med Chem Lett 16: 4834-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.06.065
BindingDB Entry DOI: 10.7270/Q2S46RK4
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50190965
PNG
(6-(4-ethoxyphenethyl)-6-cyclopentyl-dihydro-3H-pyr...)
Show SMILES CCOc1ccc(CCC2(CC(=O)CC(=O)O2)C2CCCC2)cc1
Show InChI InChI=1S/C20H26O4/c1-2-23-18-9-7-15(8-10-18)11-12-20(16-5-3-4-6-16)14-17(21)13-19(22)24-20/h7-10,16H,2-6,11-14H2,1H3
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n/an/a 2.90E+3n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory activity against HCV 1b BK NS5B deltaC21 RNA polymerase


Bioorg Med Chem Lett 16: 4834-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.06.065
BindingDB Entry DOI: 10.7270/Q2S46RK4
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50190971
PNG
(6-(3-ethylphenethyl)-6-cyclopentyl-dihydro-3H-pyra...)
Show SMILES CCc1cccc(CCC2(CC(=O)CC(=O)O2)C2CCCC2)c1
Show InChI InChI=1S/C20H26O3/c1-2-15-6-5-7-16(12-15)10-11-20(17-8-3-4-9-17)14-18(21)13-19(22)23-20/h5-7,12,17H,2-4,8-11,13-14H2,1H3
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n/an/a 3.60E+3n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory activity against HCV 1b BK NS5B deltaC21 RNA polymerase


Bioorg Med Chem Lett 16: 4834-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.06.065
BindingDB Entry DOI: 10.7270/Q2S46RK4
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50190950
PNG
(6-(4-isopropylphenethyl)-6-cyclopentyl-dihydro-3H-...)
Show SMILES CC(C)c1ccc(CCC2(CC(=O)CC(=O)O2)C2CCCC2)cc1
Show InChI InChI=1S/C21H28O3/c1-15(2)17-9-7-16(8-10-17)11-12-21(18-5-3-4-6-18)14-19(22)13-20(23)24-21/h7-10,15,18H,3-6,11-14H2,1-2H3
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n/an/a 4.30E+3n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory activity against HCV 1b BK NS5B deltaC21 RNA polymerase


Bioorg Med Chem Lett 16: 4834-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.06.065
BindingDB Entry DOI: 10.7270/Q2S46RK4
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50190954
PNG
(6-(3-chlorophenethyl)-6-cyclopentyl-dihydro-3H-pyr...)
Show SMILES Clc1cccc(CCC2(CC(=O)CC(=O)O2)C2CCCC2)c1
Show InChI InChI=1S/C18H21ClO3/c19-15-7-3-4-13(10-15)8-9-18(14-5-1-2-6-14)12-16(20)11-17(21)22-18/h3-4,7,10,14H,1-2,5-6,8-9,11-12H2
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n/an/a 5.00E+3n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory activity against HCV 1b BK NS5B deltaC21 RNA polymerase


Bioorg Med Chem Lett 16: 4834-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.06.065
BindingDB Entry DOI: 10.7270/Q2S46RK4
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50190960
PNG
(6-(4-hydroxyphenethyl)-6-cyclopentyl-dihydro-3H-py...)
Show SMILES Oc1ccc(CCC2(CC(=O)CC(=O)O2)C2CCCC2)cc1
Show InChI InChI=1S/C18H22O4/c19-15-7-5-13(6-8-15)9-10-18(14-3-1-2-4-14)12-16(20)11-17(21)22-18/h5-8,14,19H,1-4,9-12H2
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n/an/a 8.20E+3n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory activity against HCV 1b BK NS5B deltaC21 RNA polymerase


Bioorg Med Chem Lett 16: 4834-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.06.065
BindingDB Entry DOI: 10.7270/Q2S46RK4
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50190958
PNG
(6-(4-methoxyphenethyl)-6-cyclopentyl-dihydro-3H-py...)
Show SMILES COc1ccc(CCC2(CC(=O)CC(=O)O2)C2CCCC2)cc1
Show InChI InChI=1S/C19H24O4/c1-22-17-8-6-14(7-9-17)10-11-19(15-4-2-3-5-15)13-16(20)12-18(21)23-19/h6-9,15H,2-5,10-13H2,1H3
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n/an/a 9.70E+3n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory activity against HCV 1b BK NS5B deltaC21 RNA polymerase


Bioorg Med Chem Lett 16: 4834-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.06.065
BindingDB Entry DOI: 10.7270/Q2S46RK4
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50190962
PNG
(6-cyclopentyl-6-(2-m-tolyl-ethyl)-dihydro-pyran-2,...)
Show SMILES Cc1cccc(CCC2(CC(=O)CC(=O)O2)C2CCCC2)c1
Show InChI InChI=1S/C19H24O3/c1-14-5-4-6-15(11-14)9-10-19(16-7-2-3-8-16)13-17(20)12-18(21)22-19/h4-6,11,16H,2-3,7-10,12-13H2,1H3
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n/an/a 2.30E+4n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory activity against HCV 1b BK NS5B deltaC21 RNA polymerase


Bioorg Med Chem Lett 16: 4834-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.06.065
BindingDB Entry DOI: 10.7270/Q2S46RK4
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50190959
PNG
(6-cyclopentyl-6-phenethyl-dihydro-3H-pyran-2,4-dio...)
Show SMILES O=C1CC(=O)OC(CCc2ccccc2)(C1)C1CCCC1
Show InChI InChI=1S/C18H22O3/c19-16-12-17(20)21-18(13-16,15-8-4-5-9-15)11-10-14-6-2-1-3-7-14/h1-3,6-7,15H,4-5,8-13H2
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n/an/a 4.80E+4n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory activity against HCV 1b BK NS5B deltaC21 RNA polymerase


Bioorg Med Chem Lett 16: 4834-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.06.065
BindingDB Entry DOI: 10.7270/Q2S46RK4
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50190955
PNG
(6-(4-methoxyphenethyl)-6-propyl-dihydro-3H-pyran-2...)
Show SMILES CCCC1(CCc2ccc(OC)cc2)CC(=O)CC(=O)O1
Show InChI InChI=1S/C17H22O4/c1-3-9-17(12-14(18)11-16(19)21-17)10-8-13-4-6-15(20-2)7-5-13/h4-7H,3,8-12H2,1-2H3
UniProtKB/TrEMBL

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


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Article
PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory activity against HCV 1b BK NS5B deltaC21 RNA polymerase


Bioorg Med Chem Lett 16: 4834-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.06.065
BindingDB Entry DOI: 10.7270/Q2S46RK4
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50190949
PNG
(6-(4-hydroxyphenethyl)-6-cyclohexyl-dihydro-3H-pyr...)
Show SMILES Oc1ccc(CCC2(CC(=O)CC(=O)O2)C2CCCCC2)cc1
Show InChI InChI=1S/C19H24O4/c20-16-8-6-14(7-9-16)10-11-19(15-4-2-1-3-5-15)13-17(21)12-18(22)23-19/h6-9,15,20H,1-5,10-13H2
UniProtKB/TrEMBL

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UniChem

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n/an/a 5.20E+4n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory activity against HCV 1b BK NS5B deltaC21 RNA polymerase


Bioorg Med Chem Lett 16: 4834-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.06.065
BindingDB Entry DOI: 10.7270/Q2S46RK4
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50190970
PNG
(6-(4-hydroxyphenethyl)-6-cyclobutyl-dihydro-3H-pyr...)
Show SMILES Oc1ccc(CCC2(CC(=O)CC(=O)O2)C2CCC2)cc1
Show InChI InChI=1S/C17H20O4/c18-14-6-4-12(5-7-14)8-9-17(13-2-1-3-13)11-15(19)10-16(20)21-17/h4-7,13,18H,1-3,8-11H2
UniProtKB/TrEMBL

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PubMed
n/an/a 9.30E+4n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory activity against HCV 1b BK NS5B deltaC21 RNA polymerase


Bioorg Med Chem Lett 16: 4834-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.06.065
BindingDB Entry DOI: 10.7270/Q2S46RK4
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50190961
PNG
(6-(4-hydroxyphenethyl)-6-methyl-dihydro-3H-pyran-2...)
Show SMILES CC1(CCc2ccc(O)cc2)CC(=O)CC(=O)O1
Show InChI InChI=1S/C14H16O4/c1-14(9-12(16)8-13(17)18-14)7-6-10-2-4-11(15)5-3-10/h2-5,15H,6-9H2,1H3
UniProtKB/TrEMBL

B.MOAD
GoogleScholar
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PC cid
PC sid
UniChem

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Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory activity against HCV 1b BK NS5B deltaC21 RNA polymerase


Bioorg Med Chem Lett 16: 4834-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.06.065
BindingDB Entry DOI: 10.7270/Q2S46RK4
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%