Compile Data Set for Download or QSAR
maximum 50k data
Found 33 Enz. Inhib. hit(s) with all data for entry = 2059
TargetMitogen-activated protein kinase 11(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM16530(2-arylpyridazin-3-one, 36 | N-{3-[(2-chlorophenyl)...)
Affinity DataIC50:  2nMAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM16524(2-arylpyridazin-3-one, 30 | 2-{3-[(2-chlorophenyl)...)
Affinity DataIC50:  5nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM16529(2-arylpyridazin-3-one, 35 | N-{3-[(2-chlorophenyl)...)
Affinity DataIC50:  8nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM16525(2-arylpyridazin-3-one, 31 | 2-{3-[(2-chloro-4-fluo...)
Affinity DataIC50:  9nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM16528(2-arylpyridazin-3-one, 34 | N-{3-[(2-chlorophenyl)...)
Affinity DataIC50:  11nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM16524(2-arylpyridazin-3-one, 30 | 2-{3-[(2-chlorophenyl)...)
Affinity DataIC50:  15nMAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM16530(2-arylpyridazin-3-one, 36 | N-{3-[(2-chlorophenyl)...)
Affinity DataIC50:  20nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM16525(2-arylpyridazin-3-one, 31 | 2-{3-[(2-chloro-4-fluo...)
Affinity DataIC50:  20nMAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM16526(2-amino-N-{3-[(2-chlorophenyl)[1-(2-chlorophenyl)-...)
Affinity DataIC50:  20nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM16529(2-arylpyridazin-3-one, 35 | N-{3-[(2-chlorophenyl)...)
Affinity DataIC50:  29nMAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM16527(2-arylpyridazin-3-one, 33 | N-{3-[(2-chlorophenyl)...)
Affinity DataIC50:  29nMAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM16528(2-arylpyridazin-3-one, 34 | N-{3-[(2-chlorophenyl)...)
Affinity DataIC50:  31nMAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM16527(2-arylpyridazin-3-one, 33 | N-{3-[(2-chlorophenyl)...)
Affinity DataIC50:  35nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM16526(2-amino-N-{3-[(2-chlorophenyl)[1-(2-chlorophenyl)-...)
Affinity DataIC50:  41nMAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM16521(2-arylpyridazin-3-one, 27 | 6-[(2-chloro-4-fluorop...)
Affinity DataIC50:  135nMAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM16517(2-(2-chlorophenyl)-6-[(2-fluorophenyl)sulfanyl]-2,...)
Affinity DataIC50:  140nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM16521(2-arylpyridazin-3-one, 27 | 6-[(2-chloro-4-fluorop...)
Affinity DataIC50:  168nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM16522(2-arylpyridazin-3-one, 28 | 6-[(3-aminopropyl)(2-c...)
Affinity DataIC50:  197nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM16522(2-arylpyridazin-3-one, 28 | 6-[(3-aminopropyl)(2-c...)
Affinity DataIC50:  211nMAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM16518(2-(4-chloro-2-methylphenyl)-6-[(2,4-difluorophenyl...)
Affinity DataIC50:  310nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM16517(2-(2-chlorophenyl)-6-[(2-fluorophenyl)sulfanyl]-2,...)
Affinity DataIC50:  450nMAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM16515(2-(2-chlorophenyl)-6-[(2-methylphenyl)amino]-2,3-d...)
Affinity DataIC50:  450nMAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM16523(2-(2-chlorophenyl)-6-[(2-chlorophenyl)(3-{[(2,3,4-...)
Affinity DataIC50:  490nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM16514(2-(2-chlorophenyl)-6-[(2-ethylphenyl)amino]-2,3-di...)
Affinity DataIC50:  560nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM16523(2-(2-chlorophenyl)-6-[(2-chlorophenyl)(3-{[(2,3,4-...)
Affinity DataIC50:  600nMAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM16515(2-(2-chlorophenyl)-6-[(2-methylphenyl)amino]-2,3-d...)
Affinity DataIC50:  760nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM16513(2-(2-chlorophenyl)-6-[(2-chlorophenyl)amino]-2,3-d...)
Affinity DataIC50:  790nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM16518(2-(4-chloro-2-methylphenyl)-6-[(2,4-difluorophenyl...)
Affinity DataIC50:  850nMAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM16516(2-(2-chlorophenyl)-6-[(2-methoxyphenyl)amino]-2,3-...)
Affinity DataIC50:  920nMAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM16513(2-(2-chlorophenyl)-6-[(2-chlorophenyl)amino]-2,3-d...)
Affinity DataIC50:  990nMAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM16519(2-(4-chloro-2-methylphenyl)-6-[(4-chlorophenyl)sul...)
Affinity DataIC50:  2.00E+3nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM16516(2-(2-chlorophenyl)-6-[(2-methoxyphenyl)amino]-2,3-...)
Affinity DataIC50:  2.40E+3nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM16520(2-(2-chlorophenyl)-6-{[(2-methylphenyl)methyl]amin...)
Affinity DataIC50:  3.50E+3nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed