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Found 13 Enz. Inhib. hit(s) with all data for entry = 2057
TargetCathepsin B(Bos taurus (bovine))
Osaka University Of Pharmaceutical Sciences

LigandPNGBDBM16499((2S)-2-[(2S,3S)-2-{[(2S,3S)-3-(ethoxycarbonyl)oxir...)
Affinity DataIC50:  23nMpH: 6.0 T: 2°CAssay Description:Inhibitory activities (IC50, concentration of 50% inhibition) of compounds for bovine CB in vitro were determined by monitoring the cleavage of fluor...More data for this Ligand-Target Pair
TargetCathepsin B(Bos taurus (bovine))
Osaka University Of Pharmaceutical Sciences

LigandPNGBDBM16500((2S)-2-[(2S,3S)-2-{[(2S,3S)-3-(ethoxycarbonyl)oxir...)
Affinity DataIC50:  24nMpH: 6.0 T: 2°CAssay Description:Inhibitory activities (IC50, concentration of 50% inhibition) of compounds for bovine CB in vitro were determined by monitoring the cleavage of fluor...More data for this Ligand-Target Pair
TargetCathepsin B(Bos taurus (bovine))
Osaka University Of Pharmaceutical Sciences

LigandPNGBDBM16502((2S)-1-[(2S,3S)-2-{[(2S,3S)-3-(benzylcarbamoyl)oxi...)
Affinity DataIC50:  29nMpH: 6.0 T: 2°CAssay Description:Inhibitory activities (IC50, concentration of 50% inhibition) of compounds for bovine CB in vitro were determined by monitoring the cleavage of fluor...More data for this Ligand-Target Pair
TargetCathepsin B(Bos taurus (bovine))
Osaka University Of Pharmaceutical Sciences

LigandPNGBDBM16509((2S)-1-[(2S,3S)-3-methyl-2-{[(2S,3S)-3-(propylcarb...)
Affinity DataIC50:  38nMpH: 6.0 T: 2°CAssay Description:Inhibitory activities (IC50, concentration of 50% inhibition) of compounds for bovine CB in vitro were determined by monitoring the cleavage of fluor...More data for this Ligand-Target Pair
TargetCathepsin B(Bos taurus (bovine))
Osaka University Of Pharmaceutical Sciences

LigandPNGBDBM16510((2S,3S)-3-[[(1S)-1-(isoamylcarbamoyl)-3-methyl-but...)
Affinity DataIC50:  40nMpH: 6.0 T: 2°CAssay Description:Inhibitory activities (IC50, concentration of 50% inhibition) of compounds for bovine CB in vitro were determined by monitoring the cleavage of fluor...More data for this Ligand-Target Pair
TargetCathepsin B(Bos taurus (bovine))
Osaka University Of Pharmaceutical Sciences

LigandPNGBDBM16508((2S)-1-[(2S,3S)-2-{[(2S,3S)-3-(ethoxycarbonyl)oxir...)
Affinity DataIC50:  120nMpH: 6.0 T: 2°CAssay Description:Inhibitory activities (IC50, concentration of 50% inhibition) of compounds for bovine CB in vitro were determined by monitoring the cleavage of fluor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Bos taurus (bovine))
Osaka University Of Pharmaceutical Sciences

LigandPNGBDBM16501((2S)-2-[(2S,3R)-2-{[(2S,3S)-3-(ethoxycarbonyl)oxir...)
Affinity DataIC50:  410nMpH: 6.0 T: 2°CAssay Description:Inhibitory activities (IC50, concentration of 50% inhibition) of compounds for bovine CB in vitro were determined by monitoring the cleavage of fluor...More data for this Ligand-Target Pair
TargetCathepsin B(Bos taurus (bovine))
Osaka University Of Pharmaceutical Sciences

LigandPNGBDBM16504(CA inhibitor 7 | CA073 | PrNH-tES-Ile-Pro-OBzl | b...)
Affinity DataIC50:  9.10E+3nMpH: 6.0 T: 2°CAssay Description:Inhibitory activities (IC50, concentration of 50% inhibition) of compounds for bovine CB in vitro were determined by monitoring the cleavage of fluor...More data for this Ligand-Target Pair
TargetCathepsin B(Bos taurus (bovine))
Osaka University Of Pharmaceutical Sciences

LigandPNGBDBM16506((2S)-1-(2-{[(2S,3S)-3-(ethoxycarbonyl)oxiran-2-yl]...)
Affinity DataIC50:  1.53E+4nMpH: 6.0 T: 2°CAssay Description:Inhibitory activities (IC50, concentration of 50% inhibition) of compounds for bovine CB in vitro were determined by monitoring the cleavage of fluor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Bos taurus (bovine))
Osaka University Of Pharmaceutical Sciences

LigandPNGBDBM16497((2S,3S)-2-{[(2S,3S)-3-(ethoxycarbonyl)oxiran-2-yl]...)
Affinity DataIC50:  2.40E+4nMpH: 6.0 T: 2°CAssay Description:Inhibitory activities (IC50, concentration of 50% inhibition) of compounds for bovine CB in vitro were determined by monitoring the cleavage of fluor...More data for this Ligand-Target Pair
TargetCathepsin B(Bos taurus (bovine))
Osaka University Of Pharmaceutical Sciences

LigandPNGBDBM16505(BzlNH-tES-Ile-Pro-OBzl | CA inhibitor 8 | CA077 | ...)
Affinity DataIC50:  4.60E+4nMpH: 6.0 T: 2°CAssay Description:Inhibitory activities (IC50, concentration of 50% inhibition) of compounds for bovine CB in vitro were determined by monitoring the cleavage of fluor...More data for this Ligand-Target Pair
TargetCathepsin B(Bos taurus (bovine))
Osaka University Of Pharmaceutical Sciences

LigandPNGBDBM16503(CA inhibitor 6 | CA074Me | PrNH-tES-Ile-Pro-OMe | ...)
Affinity DataIC50:  6.80E+4nMpH: 6.0 T: 2°CAssay Description:Inhibitory activities (IC50, concentration of 50% inhibition) of compounds for bovine CB in vitro were determined by monitoring the cleavage of fluor...More data for this Ligand-Target Pair
TargetCathepsin B(Bos taurus (bovine))
Osaka University Of Pharmaceutical Sciences

LigandPNGBDBM16511((2S)-1-[(2S)-2-{[(2S,3S)-3-{[(1S)-1-({[(2-methoxy-...)
Affinity DatapH: 6.0 T: 2°CAssay Description:Inhibitory activities (IC50, concentration of 50% inhibition) of compounds for bovine CB in vitro were determined by monitoring the cleavage of fluor...More data for this Ligand-Target Pair