Compile Data Set for Download or QSAR
maximum 50k data
Found 36 Enz. Inhib. hit(s) with all data for entry = 50037899
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197428(4-[(2-{[4-((9S,11R,13S,14S,17S)-17-hydroxy-13-meth...)
Affinity DataKi:  0.5nMAssay Description:Displacement of radiolabeled Dexamethasone from human GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197435(CHEMBL387814 | [4-({[4-((9S,11R,13S,14S,17S)-17-hy...)
Affinity DataKi:  0.600nMAssay Description:Displacement of radiolabeled Dexamethasone from human GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197433(4-{[(4-bromo-phenyl)-(2-{[4-((9S,11R,13S,14S,17S)-...)
Affinity DataKi:  0.900nMAssay Description:Displacement of radiolabeled Dexamethasone from human GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
Affinity DataKi:  1.10nMAssay Description:Displacement of radiolabeled Dexamethasone from human GRMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197434(4-{[benzyl-(2-{[4-((9S,11R,13S,14S,17S)-17-hydroxy...)
Affinity DataKi:  1.10nMAssay Description:Displacement of radiolabeled Dexamethasone from human GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197425(CHEMBL440227 | [4-({[4-((9S,11R,13S,14S,17S)-17-hy...)
Affinity DataKi:  1.80nMAssay Description:Displacement of radiolabeled Dexamethasone from human GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197427(4-({[4-((9S,11R,13S,14S,17S)-17-hydroxy-13-methyl-...)
Affinity DataKi:  1.80nMAssay Description:Displacement of radiolabeled Dexamethasone from human GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197431(4-(2-{[4-((9S,11R,13S,14S,17S)-17-hydroxy-13-methy...)
Affinity DataKi:  2.70nMAssay Description:Displacement of radiolabeled Dexamethasone from human GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197429(3-({[4-((9S,11R,13S,14S,17S)-17-hydroxy-13-methyl-...)
Affinity DataKi:  3nMAssay Description:Displacement of radiolabeled Dexamethasone from human GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197432((4R)-4-[(1S,2S,5S,7R,9R,10R,11R,14R,16S)-9,16-dihy...)
Affinity DataKi:  4nMAssay Description:Displacement of radiolabeled Dexamethasone from human GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197425(CHEMBL440227 | [4-({[4-((9S,11R,13S,14S,17S)-17-hy...)
Affinity DataKi:  4.40nMAssay Description:Inhibition of human GR expressed in hGRAF cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197426(5-{[4-((9S,11R,13S,14S,17S)-17-hydroxy-13-methyl-3...)
Affinity DataKi:  4.80nMAssay Description:Displacement of radiolabeled Dexamethasone from human GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
Affinity DataKi:  5nMAssay Description:Inhibition of human GR expressed in hGRAF cellsMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197427(4-({[4-((9S,11R,13S,14S,17S)-17-hydroxy-13-methyl-...)
Affinity DataKi:  12nMAssay Description:Inhibition of human GR expressed in hGRAF cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197432((4R)-4-[(1S,2S,5S,7R,9R,10R,11R,14R,16S)-9,16-dihy...)
Affinity DataKi:  15nMAssay Description:Inhibition of human GR expressed in hGRAF cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197426(5-{[4-((9S,11R,13S,14S,17S)-17-hydroxy-13-methyl-3...)
Affinity DataKi:  15nMAssay Description:Inhibition of human GR expressed in hGRAF cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197428(4-[(2-{[4-((9S,11R,13S,14S,17S)-17-hydroxy-13-meth...)
Affinity DataKi:  21nMAssay Description:Inhibition of human GR expressed in hGRAF cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197429(3-({[4-((9S,11R,13S,14S,17S)-17-hydroxy-13-methyl-...)
Affinity DataKi:  30nMAssay Description:Inhibition of human GR expressed in hGRAF cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197430(CHEMBL245267 | [2-(2-{[4-((9S,11R,13S,14S,17S)-17-...)
Affinity DataKi:  31nMAssay Description:Inhibition of human GR transcriptional activation by HepTAT cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197425(CHEMBL440227 | [4-({[4-((9S,11R,13S,14S,17S)-17-hy...)
Affinity DataKi:  32nMAssay Description:Inhibition of human GR transcriptional activation by HepTAT cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197433(4-{[(4-bromo-phenyl)-(2-{[4-((9S,11R,13S,14S,17S)-...)
Affinity DataKi:  33nMAssay Description:Inhibition of human GR expressed in hGRAF cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197433(4-{[(4-bromo-phenyl)-(2-{[4-((9S,11R,13S,14S,17S)-...)
Affinity DataKi:  33nMAssay Description:Inhibition of human GR transcriptional activation by HepTAT cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197430(CHEMBL245267 | [2-(2-{[4-((9S,11R,13S,14S,17S)-17-...)
Affinity DataKi:  35nMAssay Description:Displacement of radiolabeled Dexamethasone from human GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197435(CHEMBL387814 | [4-({[4-((9S,11R,13S,14S,17S)-17-hy...)
Affinity DataKi:  36nMAssay Description:Inhibition of human GR transcriptional activation by HepTAT cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197434(4-{[benzyl-(2-{[4-((9S,11R,13S,14S,17S)-17-hydroxy...)
Affinity DataKi:  39nMAssay Description:Inhibition of human GR expressed in hGRAF cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197427(4-({[4-((9S,11R,13S,14S,17S)-17-hydroxy-13-methyl-...)
Affinity DataKi:  52nMAssay Description:Inhibition of human GR transcriptional activation by HepTAT cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197434(4-{[benzyl-(2-{[4-((9S,11R,13S,14S,17S)-17-hydroxy...)
Affinity DataKi:  57nMAssay Description:Inhibition of human GR transcriptional activation by HepTAT cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197428(4-[(2-{[4-((9S,11R,13S,14S,17S)-17-hydroxy-13-meth...)
Affinity DataKi:  64nMAssay Description:Inhibition of human GR transcriptional activation by HepTAT cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197431(4-(2-{[4-((9S,11R,13S,14S,17S)-17-hydroxy-13-methy...)
Affinity DataKi:  75nMAssay Description:Inhibition of human GR transcriptional activation by HepTAT cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197435(CHEMBL387814 | [4-({[4-((9S,11R,13S,14S,17S)-17-hy...)
Affinity DataKi:  90nMAssay Description:Inhibition of human GR expressed in hGRAF cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197431(4-(2-{[4-((9S,11R,13S,14S,17S)-17-hydroxy-13-methy...)
Affinity DataKi:  91.8nMAssay Description:Inhibition of human GR expressed in hGRAF cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197429(3-({[4-((9S,11R,13S,14S,17S)-17-hydroxy-13-methyl-...)
Affinity DataKi:  112nMAssay Description:Inhibition of human GR transcriptional activation by HepTAT cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197426(5-{[4-((9S,11R,13S,14S,17S)-17-hydroxy-13-methyl-3...)
Affinity DataKi:  127nMAssay Description:Inhibition of human GR transcriptional activation by HepTAT cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
Affinity DataKi:  169nMAssay Description:Inhibition of human GR transcriptional activation by HepTAT cellsMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197432((4R)-4-[(1S,2S,5S,7R,9R,10R,11R,14R,16S)-9,16-dihy...)
Affinity DataKi:  200nMAssay Description:Inhibition of human GR transcriptional activation by HepTAT cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197430(CHEMBL245267 | [2-(2-{[4-((9S,11R,13S,14S,17S)-17-...)
Affinity DataKi:  765nMAssay Description:Inhibition of human GR expressed in hGRAF cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed