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Found 20 Enz. Inhib. hit(s) with all data for entry = 50037776
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50370763(CHEMBL1203926)
Affinity DataIC50:  9nMAssay Description:Inhibition of HCV NS5B RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50199051(3-benzyloxy-12-cyclohexyl-6,7-dihydro-5-oxa-7a-aza...)
Affinity DataIC50:  17nMAssay Description:Inhibition of HCV NS5B RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50370761(CHEMBL1204385)
Affinity DataIC50:  18nMAssay Description:Inhibition of HCV NS5B RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50199043(13-cyclohexyl-5-methyl-6,7-dihydro-5H-benzo[5,6][1...)
Affinity DataIC50:  19nMAssay Description:Inhibition of HCV NS5B RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50370762(CHEMBL1203925)
Affinity DataIC50:  21nMAssay Description:Inhibition of HCV NS5B RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50199042(13-cyclohexyl-5-(dimethylcarbamoylmethyl)-6,7-dihy...)
Affinity DataIC50:  24nMAssay Description:Inhibition of HCV NS5B RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50199058(12-cyclohexyl-6,7-dihydro-5-oxa-7a-azadibenzo[a,e]...)
Affinity DataIC50:  26nMAssay Description:Inhibition of HCV NS5B RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50199046(13-cyclohexyl-5-(2-phenylethyl)-6,7-dihydro-5H-ben...)
Affinity DataIC50:  26nMAssay Description:Inhibition of HCV NS5B RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50199048(13-cyclohexyl-5-iso-propyl-6,7-dihydro-5H-benzo[5,...)
Affinity DataIC50:  36nMAssay Description:Inhibition of HCV NS5B RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50199049(12-cyclohexyl-6,7-dihydro-5-thia-7a-azadibenzo[a,e...)
Affinity DataIC50:  38nMAssay Description:Inhibition of HCV NS5B RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50199047(13-cyclohexyl-5-benzyl-6,7-dihydro-5H-benzo[5,6][1...)
Affinity DataIC50:  41nMAssay Description:Inhibition of HCV NS5B RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50199050(2-[(12-cyclohexyl-6,7-dihydro-5-oxa-7a-aza-dibenzo...)
Affinity DataIC50:  46nMAssay Description:Inhibition of HCV NS5B RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50199054(14-cyclohexyl-7,8-dihydro-6H-indole[1,2e][1,5]benz...)
Affinity DataIC50:  47nMAssay Description:Inhibition of HCV NS5B RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50199056(13-cyclohexyl-6,7-dihydro-5H-benzo[3,4]azepino[1,2...)
Affinity DataIC50:  77nMAssay Description:Inhibition of HCV NS5B RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50199053(5-acetyl-13-cyclohexyl-6,7-dihydro-5H-benzo[5,6][1...)
Affinity DataIC50:  120nMAssay Description:Inhibition of HCV NS5B RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50199059(2-(4-(benzyloxy)phenyl)-3-cyclohexyl-1-methyl-1H-i...)
Affinity DataIC50:  120nMAssay Description:Inhibition of HCV NS5B RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50199045(12-cyclohexyl-5,6-dihydroindolo[2,1-a]isoquinoline...)
Affinity DataIC50:  140nMAssay Description:Inhibition of HCV NS5B RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50199052(11-cyclohexyl-5-oxa-6a-azabenzo[a]fluorene-8-carbo...)
Affinity DataIC50:  140nMAssay Description:Inhibition of HCV NS5B RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50199057(11-cyclohexyl-6H-isoindolo[2,1-a]indole-3-carboxyl...)
Affinity DataIC50:  210nMAssay Description:Inhibition of HCV NS5B RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50181950(2-(4-(benzyloxy)phenyl)-1-cyclohexyl-1H-benzo[d]im...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of HCV NS5B RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed