Compile Data Set for Download or QSAR
maximum 50k data
Found 84 Enz. Inhib. hit(s) with all data for entry = 50019304
Target72 kDa type IV collagenase(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50203526((6S,7S)-6-(4-phenyl-3,6-dihydro-2H-pyridine-1-carb...)
Affinity DataIC50:  5nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50203538((6S,7S)-6-(3-phenyl-2,5-dihydro-pyrrole-1-carbonyl...)
Affinity DataIC50:  13nMAssay Description:Inhibition of Her2 sheddase activity in BT474 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50203538((6S,7S)-6-(3-phenyl-2,5-dihydro-pyrrole-1-carbonyl...)
Affinity DataIC50:  13nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50203526((6S,7S)-6-(4-phenyl-3,6-dihydro-2H-pyridine-1-carb...)
Affinity DataIC50:  18nMAssay Description:Inhibition of Her2 sheddase activity in BT474 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50203538((6S,7S)-6-(3-phenyl-2,5-dihydro-pyrrole-1-carbonyl...)
Affinity DataIC50:  23nMAssay Description:Inhibition of ADAM10More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50203526((6S,7S)-6-(4-phenyl-3,6-dihydro-2H-pyridine-1-carb...)
Affinity DataIC50:  33nMAssay Description:Inhibition of ADAM10More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50203527((6S,7S)-methyl 7-(hydroxycarbamoyl)-6-(4-phenyl-1,...)
Affinity DataIC50:  39nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50203529((6S,7S)-6-(4-phenyl-piperazine-1-carbonyl)-5-aza-s...)
Affinity DataIC50:  52nMAssay Description:Inhibition of Her2 sheddase activity in BT474 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50203527((6S,7S)-methyl 7-(hydroxycarbamoyl)-6-(4-phenyl-1,...)
Affinity DataIC50:  59nMAssay Description:Inhibition of ADAM10More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50203528((6S,7S)-N-hydroxy-5-methyl-6-[(4-phenyl-3,6-dihydr...)
Affinity DataIC50:  64nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50203527((6S,7S)-methyl 7-(hydroxycarbamoyl)-6-(4-phenyl-1,...)
Affinity DataIC50:  68nMAssay Description:Inhibition of Her2 sheddase activity in BT474 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50203538((6S,7S)-6-(3-phenyl-2,5-dihydro-pyrrole-1-carbonyl...)
Affinity DataIC50:  77nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50203528((6S,7S)-N-hydroxy-5-methyl-6-[(4-phenyl-3,6-dihydr...)
Affinity DataIC50:  77nMAssay Description:Inhibition of ADAM10More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50203533((6S,7S)-N-hydroxy-6-((R)-3-phenylpyrrolidine-1-car...)
Affinity DataIC50:  92nMAssay Description:Inhibition of Her2 sheddase activity in BT474 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50203533((6S,7S)-N-hydroxy-6-((R)-3-phenylpyrrolidine-1-car...)
Affinity DataIC50:  97nMAssay Description:Inhibition of ADAM10More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50203530((6S,7S)-N-hydroxy-6-{[4-(2-methyl-4-nitrophenyl)pi...)
Affinity DataIC50:  110nMAssay Description:Inhibition of ADAM10More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50203526((6S,7S)-6-(4-phenyl-3,6-dihydro-2H-pyridine-1-carb...)
Affinity DataIC50:  113nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50203529((6S,7S)-6-(4-phenyl-piperazine-1-carbonyl)-5-aza-s...)
Affinity DataIC50:  120nMAssay Description:Inhibition of ADAM10More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50203531((6S,7S)-N-hydroxy-6-{[4-(2-methyl-4-nitrophenyl)-3...)
Affinity DataIC50:  130nMAssay Description:Inhibition of ADAM10More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50203537((6S,7S)-6-(4-phenyl-piperidine-1-carbonyl)-5-aza-s...)
Affinity DataIC50:  140nMAssay Description:Inhibition of Her2 sheddase activity in BT474 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50203534((6S,7S)-N-hydroxy-5-methyl-6-(4-phenylpiperazine-1...)
Affinity DataIC50:  150nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50203528((6S,7S)-N-hydroxy-5-methyl-6-[(4-phenyl-3,6-dihydr...)
Affinity DataIC50:  160nMAssay Description:Inhibition of Her2 sheddase activity in BT474 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50203530((6S,7S)-N-hydroxy-6-{[4-(2-methyl-4-nitrophenyl)pi...)
Affinity DataIC50:  160nMAssay Description:Inhibition of Her2 sheddase activity in BT474 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50203529((6S,7S)-6-(4-phenyl-piperazine-1-carbonyl)-5-aza-s...)
Affinity DataIC50:  200nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50203534((6S,7S)-N-hydroxy-5-methyl-6-(4-phenylpiperazine-1...)
Affinity DataIC50:  230nMAssay Description:Inhibition of Her2 sheddase activity in BT474 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50203535((6S,7S)-N-hydroxy-6-(3,4,10,10a-tetrahydropyrazino...)
Affinity DataIC50:  280nMAssay Description:Inhibition of Her2 sheddase activity in BT474 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50203531((6S,7S)-N-hydroxy-6-{[4-(2-methyl-4-nitrophenyl)-3...)
Affinity DataIC50:  300nMAssay Description:Inhibition of Her2 sheddase activity in BT474 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50203534((6S,7S)-N-hydroxy-5-methyl-6-(4-phenylpiperazine-1...)
Affinity DataIC50:  310nMAssay Description:Inhibition of ADAM10More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50203537((6S,7S)-6-(4-phenyl-piperidine-1-carbonyl)-5-aza-s...)
Affinity DataIC50:  320nMAssay Description:Inhibition of ADAM10More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50203535((6S,7S)-N-hydroxy-6-(3,4,10,10a-tetrahydropyrazino...)
Affinity DataIC50:  330nMAssay Description:Inhibition of ADAM10More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50203535((6S,7S)-N-hydroxy-6-(3,4,10,10a-tetrahydropyrazino...)
Affinity DataIC50:  350nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50203527((6S,7S)-methyl 7-(hydroxycarbamoyl)-6-(4-phenyl-1,...)
Affinity DataIC50:  428nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50203537((6S,7S)-6-(4-phenyl-piperidine-1-carbonyl)-5-aza-s...)
Affinity DataIC50:  450nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50203538((6S,7S)-6-(3-phenyl-2,5-dihydro-pyrrole-1-carbonyl...)
Affinity DataIC50:  450nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50203536((2S,3S)-N-hydroxy-2-((R)-3-phenylpyrrolidine-1-car...)
Affinity DataIC50:  480nMAssay Description:Inhibition of ADAM10More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50203536((2S,3S)-N-hydroxy-2-((R)-3-phenylpyrrolidine-1-car...)
Affinity DataIC50:  560nMAssay Description:Inhibition of Her2 sheddase activity in BT474 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50203529((6S,7S)-6-(4-phenyl-piperazine-1-carbonyl)-5-aza-s...)
Affinity DataIC50:  650nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50082539(1-(4-Methoxy-benzenesulfonyl)-piperidine-2-carboxy...)
Affinity DataIC50:  670nMAssay Description:Inhibition of Her2 sheddase activity in BT474 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50203525((6S,7S)-N-hydroxy-6-[(5-methyl-4-phenyl-3,6-dihydr...)
Affinity DataIC50:  720nMAssay Description:Inhibition of ADAM10More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50203533((6S,7S)-N-hydroxy-6-((R)-3-phenylpyrrolidine-1-car...)
Affinity DataIC50:  960nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50203528((6S,7S)-N-hydroxy-5-methyl-6-[(4-phenyl-3,6-dihydr...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50203530((6S,7S)-N-hydroxy-6-{[4-(2-methyl-4-nitrophenyl)pi...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50203530((6S,7S)-N-hydroxy-6-{[4-(2-methyl-4-nitrophenyl)pi...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50203532((6S,7S)-5-methyl-5-aza-spiro[2.5]octane-6,7-dicarb...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50203525((6S,7S)-N-hydroxy-6-[(5-methyl-4-phenyl-3,6-dihydr...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of Her2 sheddase activity in BT474 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50203532((6S,7S)-5-methyl-5-aza-spiro[2.5]octane-6,7-dicarb...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50203526((6S,7S)-6-(4-phenyl-3,6-dihydro-2H-pyridine-1-carb...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50203538((6S,7S)-6-(3-phenyl-2,5-dihydro-pyrrole-1-carbonyl...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50203533((6S,7S)-N-hydroxy-6-((R)-3-phenylpyrrolidine-1-car...)
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50203533((6S,7S)-N-hydroxy-6-((R)-3-phenylpyrrolidine-1-car...)
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 84 total ) | Next | Last >>
Jump to: