Compile Data Set for Download or QSAR
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Found 29 Enz. Inhib. hit(s) with all data for entry = 50019351
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Medical University

Curated by ChEMBL
LigandPNGBDBM50203827(CHEMBL385583 | Dmt-Pro-Phe-D-1-Nal-NH2)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Medical University

Curated by ChEMBL
LigandPNGBDBM50232769(CHEMBL254919 | Dmt-Pro-Phe-D-2-Nal-NH2)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Medical University

Curated by ChEMBL
LigandPNGBDBM50203823(CHEMBL218433 | Dmt-Pro-Trp-D-2-Nal-NH2)
Affinity DataKi:  2.40nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Medical University

Curated by ChEMBL
LigandPNGBDBM50232769(CHEMBL254919 | Dmt-Pro-Phe-D-2-Nal-NH2)
Affinity DataKi:  7.70nMAssay Description:Displacement of [3H]DSLET from delta opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Medical University

Curated by ChEMBL
LigandPNGBDBM50203823(CHEMBL218433 | Dmt-Pro-Trp-D-2-Nal-NH2)
Affinity DataKi:  17nMAssay Description:Displacement of [3H]DSLET from delta opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Medical University

Curated by ChEMBL
LigandPNGBDBM50203827(CHEMBL385583 | Dmt-Pro-Phe-D-1-Nal-NH2)
Affinity DataKi:  27nMAssay Description:Displacement of [3H]DSLET from delta opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Medical University

Curated by ChEMBL
LigandPNGBDBM50139013((S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]...)
Affinity DataIC50:  7.70nMAssay Description:Agonist activity at mu opioid receptor by inhibition of electrically evoked muscle contraction in guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Medical University

Curated by ChEMBL
LigandPNGBDBM50139013((S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]...)
Affinity DataIC50:  15nMAssay Description:Agonist activity at delta opioid receptor by inhibition of electrically evoked muscle contraction in isolated mouse vas deferensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Medical University

Curated by ChEMBL
LigandPNGBDBM50203829(CHEMBL375068 | Dmt-Pro-Trp-D-1-Nal-NH2)
Affinity DataIC50:  16nMAssay Description:Agonist activity at mu opioid receptor by inhibition of electrically evoked muscle contraction in guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Medical University

Curated by ChEMBL
LigandPNGBDBM50095155((S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]...)
Affinity DataIC50:  17nMAssay Description:Agonist activity at mu opioid receptor by inhibition of electrically evoked muscle contraction in guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Medical University

Curated by ChEMBL
LigandPNGBDBM50095155((S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]...)
Affinity DataIC50:  26nMAssay Description:Agonist activity at delta opioid receptor by inhibition of electrically evoked muscle contraction in isolated mouse vas deferensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Medical University

Curated by ChEMBL
LigandPNGBDBM50203826(CHEMBL267211 | Tyr-Pro-Trp-D-2-Nal-NH2)
Affinity DataIC50:  3.47E+3nMAssay Description:Agonist activity at mu opioid receptor by inhibition of electrically evoked muscle contraction in guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Medical University

Curated by ChEMBL
LigandPNGBDBM50203822(CHEMBL219108 | Tyr-Pro-Trp-D-1-Nal-NH2)
Affinity DataIC50:  4.18E+3nMAssay Description:Agonist activity at mu opioid receptor by inhibition of electrically evoked muscle contraction in guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Medical University

Curated by ChEMBL
LigandPNGBDBM50203828(CHEMBL375069 | Tyr-Pro-Phe-D-1-Nal-NH2)
Affinity DataIC50: >1.00E+4nMAssay Description:Agonist activity at delta opioid receptor by inhibition of electrically evoked muscle contraction in isolated mouse vas deferensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Medical University

Curated by ChEMBL
LigandPNGBDBM50095155((S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]...)
Affinity DataEC50:  932nMAssay Description:Activity at delta opioid receptor assessed as increase in calcium level in CHO cells by aequorin luminescence based calcium assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Medical University

Curated by ChEMBL
LigandPNGBDBM50203823(CHEMBL218433 | Dmt-Pro-Trp-D-2-Nal-NH2)
Affinity DataEC50:  29nMAssay Description:Activity at delta opioid receptor assessed as increase in calcium level in CHO cells by aequorin luminescence based calcium assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Medical University

Curated by ChEMBL
LigandPNGBDBM50203826(CHEMBL267211 | Tyr-Pro-Trp-D-2-Nal-NH2)
Affinity DataEC50:  248nMAssay Description:Activity at mu opioid receptor assessed as increase in calcium level in CHO cells by aequorin luminescence based calcium assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Medical University

Curated by ChEMBL
LigandPNGBDBM50203822(CHEMBL219108 | Tyr-Pro-Trp-D-1-Nal-NH2)
Affinity DataEC50:  82nMAssay Description:Activity at mu opioid receptor assessed as increase in calcium level in CHO cells by aequorin luminescence based calcium assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Medical University

Curated by ChEMBL
LigandPNGBDBM50203828(CHEMBL375069 | Tyr-Pro-Phe-D-1-Nal-NH2)
Affinity DataEC50: >1.00E+3nMAssay Description:Activity at delta opioid receptor assessed as increase in calcium level in CHO cells by aequorin luminescence based calcium assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Medical University

Curated by ChEMBL
LigandPNGBDBM50001468((S)-3-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phen...)
Affinity DataEC50: <0.0100nMAssay Description:Activity at delta opioid receptor assessed as increase in calcium level in CHO cells by aequorin luminescence based calcium assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Medical University

Curated by ChEMBL
LigandPNGBDBM50095155((S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]...)
Affinity DataEC50:  0.00100nMAssay Description:Activity at mu opioid receptor assessed as increase in calcium level in CHO cells by aequorin luminescence based calcium assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Medical University

Curated by ChEMBL
LigandPNGBDBM50232769(CHEMBL254919 | Dmt-Pro-Phe-D-2-Nal-NH2)
Affinity DataEC50:  16nMAssay Description:Activity at delta opioid receptor assessed as increase in calcium level in CHO cells by aequorin luminescence based calcium assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Medical University

Curated by ChEMBL
LigandPNGBDBM50139013((S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]...)
Affinity DataEC50:  0.0400nMAssay Description:Activity at mu opioid receptor assessed as increase in calcium level in CHO cells by aequorin luminescence based calcium assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Medical University

Curated by ChEMBL
LigandPNGBDBM50203825(CHEMBL375070 | Tyr-Pro-Phe-D-2-Nal-NH2)
Affinity DataEC50: >1.00E+3nMAssay Description:Activity at delta opioid receptor assessed as increase in calcium level in CHO cells by aequorin luminescence based calcium assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Medical University

Curated by ChEMBL
LigandPNGBDBM50139013((S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]...)
Affinity DataEC50: >1.00E+3nMAssay Description:Activity at delta opioid receptor assessed as increase in calcium level in CHO cells by aequorin luminescence based calcium assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Medical University

Curated by ChEMBL
LigandPNGBDBM50203829(CHEMBL375068 | Dmt-Pro-Trp-D-1-Nal-NH2)
Affinity DataEC50:  1.20nMAssay Description:Activity at mu opioid receptor assessed as increase in calcium level in CHO cells by aequorin luminescence based calcium assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Medical University

Curated by ChEMBL
LigandPNGBDBM50203826(CHEMBL267211 | Tyr-Pro-Trp-D-2-Nal-NH2)
Affinity DataEC50: >1.00E+3nMAssay Description:Activity at delta opioid receptor assessed as increase in calcium level in CHO cells by aequorin luminescence based calcium assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Medical University

Curated by ChEMBL
LigandPNGBDBM50203827(CHEMBL385583 | Dmt-Pro-Phe-D-1-Nal-NH2)
Affinity DataEC50:  3.60nMAssay Description:Activity at delta opioid receptor assessed as increase in calcium level in CHO cells by aequorin luminescence based calcium assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Medical University

Curated by ChEMBL
LigandPNGBDBM50203822(CHEMBL219108 | Tyr-Pro-Trp-D-1-Nal-NH2)
Affinity DataEC50: >1.00E+3nMAssay Description:Activity at delta opioid receptor assessed as increase in calcium level in CHO cells by aequorin luminescence based calcium assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed