Compile Data Set for Download or QSAR
maximum 50k data
Found 10 Enz. Inhib. hit(s) with all data for entry = 50037907
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
University Of Kuopio

Curated by ChEMBL
LigandPNGBDBM50178769((+/-)-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-c...)
Affinity DataIC50:  280nMAssay Description:Inhibition of SIRT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
University Of Kuopio

Curated by ChEMBL
LigandPNGBDBM50178769((+/-)-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-c...)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of SIRT2More data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
University Of Kuopio

Curated by ChEMBL
LigandPNGBDBM50241186((S)-N-(1-(2-(1H-indol-3-yl)ethylamino)-1-oxopropan...)
Affinity DataIC50:  4.70E+4nMAssay Description:Inhibition of SIRT2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
University Of Kuopio

Curated by ChEMBL
LigandPNGBDBM50241185((E)-N-(1-(2-(1H-indol-3-yl)ethylamino)-2-methyl-1-...)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of SIRT2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
University Of Kuopio

Curated by ChEMBL
LigandPNGBDBM50199445((E)-N-(2-(5-fluoro-1H-indol-3-yl)ethyl)-4-(3-(4-(4...)
Affinity DataIC50:  5.10E+4nMAssay Description:Inhibition of SIRT2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
University Of Kuopio

Curated by ChEMBL
LigandPNGBDBM50241183((E)-N-(2-(1H-indol-3-yl)ethyl)-4-(3-(4-(benzyloxy)...)
Affinity DataIC50:  5.20E+4nMAssay Description:Inhibition of SIRT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
University Of Kuopio

Curated by ChEMBL
LigandPNGBDBM50241183((E)-N-(2-(1H-indol-3-yl)ethyl)-4-(3-(4-(benzyloxy)...)
Affinity DataIC50:  6.30E+4nMAssay Description:Inhibition of SIRT2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
University Of Kuopio

Curated by ChEMBL
LigandPNGBDBM50199445((E)-N-(2-(5-fluoro-1H-indol-3-yl)ethyl)-4-(3-(4-(4...)
Affinity DataIC50:  7.30E+4nMAssay Description:Inhibition of SIRT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
University Of Kuopio

Curated by ChEMBL
LigandPNGBDBM50241187((E)-N-(1-(2-(5-fluoro-1H-indol-3-yl)ethylamino)-2-...)
Affinity DataIC50:  8.00E+4nMAssay Description:Inhibition of SIRT2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
University Of Kuopio

Curated by ChEMBL
LigandPNGBDBM50241184((E)-N-(1-(2-(1H-indol-3-yl)ethylamino)-2-methyl-1-...)
Affinity DataIC50:  9.90E+4nMAssay Description:Inhibition of SIRT2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed