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Found 12 Enz. Inhib. hit(s) with all data for entry = 50019710
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50207029(CHEMBL230375 | tert-butyl 4-(4-(1H-indol-3-yl)buta...)
Affinity DataIC50:  740nMAssay Description:Inhibition of 5-LOX in rat peritoneal leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50000541((+-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea |...)
Affinity DataIC50:  830nMAssay Description:Inhibition of 5-LOX in rat peritoneal leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50207027(4-(1-benzyl-1H-indol-3-yl)-1-(piperazin-1-yl)butan...)
Affinity DataIC50:  850nMAssay Description:Inhibition of 5-LOX in rat peritoneal leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50207025(2-(1-(3,4-dichlorobenzyl)-1H-indol-3-yl)-1-morphol...)
Affinity DataIC50:  870nMAssay Description:Inhibition of 5-LOX in rat peritoneal leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50207032(4-(1-benzyl-5-chloro-2-methyl-1H-indol-3-yl)-1-mor...)
Affinity DataIC50:  950nMAssay Description:Inhibition of 5-LOX in rat peritoneal leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50207026(4-(5-chloro-2-methyl-1H-indol-3-yl)-1-morpholinobu...)
Affinity DataIC50:  1.33E+3nMAssay Description:Inhibition of 5-LOX in rat peritoneal leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50207035(4-(1H-indol-3-yl)-1-morpholinobutan-1-one | CHEMBL...)
Affinity DataIC50:  2.06E+3nMAssay Description:Inhibition of 5-LOX in rat peritoneal leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50207034(4-(1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol...)
Affinity DataIC50:  2.25E+3nMAssay Description:Inhibition of 5-LOX in rat peritoneal leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50207033(3-(2-(3-fluoro-5-(4-methoxy-tetrahydro-2H-pyran-4-...)
Affinity DataIC50:  2.38E+3nMAssay Description:Inhibition of 5-LOX in rat peritoneal leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50207028(4-(5-methoxy-2-methyl-1H-indol-3-yl)-1-morpholinob...)
Affinity DataIC50:  3.16E+3nMAssay Description:Inhibition of 5-LOX in rat peritoneal leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50207031(3-(1-benzyl-1H-indol-3-yl)-1-morpholinopropan-1-on...)
Affinity DataIC50:  3.17E+3nMAssay Description:Inhibition of 5-LOX in rat peritoneal leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50207030(4-(1-benzyl-1H-indol-3-yl)-1-morpholinobutan-1-one...)
Affinity DataIC50:  7.40E+4nMAssay Description:Inhibition of 5-LOX in rat peritoneal leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed