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Found 17 Enz. Inhib. hit(s) with all data for entry = 50019775
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50207580(CHEMBL234074 | N-[3-(5-nitro-1H-benzoimidazol-2-yl...)
Affinity DataIC50:  1.42nMAssay Description:Inhibition of NHE1 in rat platelets by Platelet swelling assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50207583(CHEMBL234279 | N-[2-(5-nitro-1H-benzoimidazol-2-yl...)
Affinity DataIC50:  4.05nMAssay Description:Inhibition of NHE1 in rat platelets by Platelet swelling assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50207572(CHEMBL234072 | N-[4-(5-nitro-1H-benzoimidazol-2-yl...)
Affinity DataIC50:  11nMAssay Description:Inhibition of NHE1 in rat platelets by Platelet swelling assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50207574(CHEMBL233048 | N-{3-(morpholine-4-sulfonyl)-4-[4-(...)
Affinity DataIC50:  27.1nMAssay Description:Inhibition of NHE1 in rat platelets by Platelet swelling assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50207579(CHEMBL232838 | N-{3-methanesulfonyl-4-[4-(5-nitro-...)
Affinity DataIC50:  27.8nMAssay Description:Inhibition of NHE1 in rat platelets by Platelet swelling assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50207570(5-guanidinocarbonyl-2-[4-(5-nitro-1H-benzoimidazol...)
Affinity DataIC50:  40.2nMAssay Description:Inhibition of NHE1 in rat platelets by Platelet swelling assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50058759(CHEMBL436559 | CHEMBL462831 | Cariporide | N-(4-Is...)
Affinity DataIC50:  65nMAssay Description:Inhibition of NHE1 in rat platelets by Platelet swelling assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50207585(2-[4-(1H-benzoimidazol-2-yl)-phenylsulfanylmethyl]...)
Affinity DataIC50:  79nMAssay Description:Inhibition of NHE1 in rat platelets by Platelet swelling assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50207576(CHEMBL232836 | N-{3-bromo-4-[4-(5-nitro-1H-benzoim...)
Affinity DataIC50:  147nMAssay Description:Inhibition of NHE1 in rat platelets by Platelet swelling assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50207569(CHEMBL434958 | N-[4-(1-methyl-1H-benzoimidazol-2-y...)
Affinity DataIC50:  264nMAssay Description:Inhibition of NHE1 in rat platelets by Platelet swelling assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50207575(CHEMBL446189 | N-[3-(1-methyl-1H-benzoimidazol-2-y...)
Affinity DataIC50:  267nMAssay Description:Inhibition of NHE1 in rat platelets by Platelet swelling assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50207577(CHEMBL233863 | N-[2-(1H-benzoimidazol-2-yl)-benzoy...)
Affinity DataIC50:  295nMAssay Description:Inhibition of NHE1 in rat platelets by Platelet swelling assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50207571(CHEMBL232443 | N-{4-[4-(5-nitro-1H-benzoimidazol-2...)
Affinity DataIC50:  332nMAssay Description:Inhibition of NHE1 in rat platelets by Platelet swelling assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50207584(CHEMBL389313 | N-[3-(1H-benzoimidazol-2-yl)-benzoy...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of NHE1 in rat platelets by Platelet swelling assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50207582(CHEMBL233862 | N-[4-(1H-benzoimidazol-2-yl)-benzoy...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of NHE1 in rat platelets by Platelet swelling assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50207578(CHEMBL232442 | N-{4-[4-(1H-benzoimidazol-2-yl)-phe...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of NHE1 in rat platelets by Platelet swelling assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50207581(CHEMBL389307 | N-[2-(1-methyl-1H-benzoimidazol-2-y...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of NHE1 in rat platelets by Platelet swelling assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed