Compile Data Set for Download or QSAR
maximum 50k data
Found 51 Enz. Inhib. hit(s) with all data for entry = 50019786
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207679(CHEMBL246258 | N-(1-(2-chloro-4-((2-(pyrrolidin-1-...)
Affinity DataIC50:  2nMAssay Description:Displacement of [125I]MCH from MCHR1 expressed in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207681(CHEMBL248297 | N-(1-(3-fluoro-4-(3-(piperidin-1-yl...)
Affinity DataIC50:  3nMAssay Description:Displacement of [125I]MCH from MCHR1 expressed in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197139(CHEMBL214021 | N-(1-(benzo[d][1,3]dioxol-5-ylmethy...)
Affinity DataIC50:  3nMAssay Description:Displacement of [125I]MCH from MCHR1 expressed in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207674(CHEMBL245844 | N-(1-(4-(3-(2,4-dioxothiazolidin-3-...)
Affinity DataIC50:  4nMAssay Description:Displacement of [125I]MCH from MCHR1 expressed in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207685(CHEMBL394639 | N-(1-(3-fluoro-4-(2-(isobutoxyimino...)
Affinity DataIC50:  15nMAssay Description:Displacement of [125I]MCH from MCHR1 expressed in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207684(CHEMBL246050 | N-(1-(4-((2-(piperidin-1-yl)ethyl)c...)
Affinity DataIC50:  17nMAssay Description:Displacement of [125I]MCH from MCHR1 expressed in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207677(CHEMBL248296 | N-(1-(4-(3-(dimethylamino)propoxy)-...)
Affinity DataIC50:  20nMAssay Description:Displacement of [125I]MCH from MCHR1 expressed in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207675(CHEMBL246464 | N-(1-(3-fluoro-4-(3-(piperidin-1-yl...)
Affinity DataIC50:  23nMAssay Description:Displacement of [125I]MCH from MCHR1 expressed in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197123(CHEMBL214768 | N-(1-(3-fluoro-4-methoxybenzyl)pipe...)
Affinity DataIC50:  24nMAssay Description:Displacement of [125I]MCH from MCHR1 expressed in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207673(CHEMBL246259 | N-(1-(2-methoxy-4-((2-(pyrrolidin-1...)
Affinity DataIC50:  26nMAssay Description:Displacement of [125I]MCH from MCHR1 expressed in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207683(CHEMBL245846 | N-(1-(3-fluoro-4-((2-(pyrrolidin-1-...)
Affinity DataIC50:  29nMAssay Description:Displacement of [125I]MCH from MCHR1 expressed in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197139(CHEMBL214021 | N-(1-(benzo[d][1,3]dioxol-5-ylmethy...)
Affinity DataIC50:  29nMAssay Description:Antagonist activity at MCHR1 assessed as inhibition of MCH-mediated calcium release in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207676(CHEMBL245642 | N-(1-(3-fluoro-4-(2-(methoxyimino)e...)
Affinity DataIC50:  31nMAssay Description:Displacement of [125I]MCH from MCHR1 expressed in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207678(CHEMBL247891 | N-(1-(4-(3-(dicyclopropylamino)prop...)
Affinity DataIC50:  51nMAssay Description:Displacement of [125I]MCH from MCHR1 expressed in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207687(CHEMBL247689 | N-(1-(3-fluoro-4-(2,2,2-trifluoroet...)
Affinity DataIC50:  64nMAssay Description:Displacement of [125I]MCH from MCHR1 expressed in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207686(CHEMBL246051 | N-(1-(4-((2-(4,4-difluoropiperidin-...)
Affinity DataIC50:  86nMAssay Description:Displacement of [125I]MCH from MCHR1 expressed in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207681(CHEMBL248297 | N-(1-(3-fluoro-4-(3-(piperidin-1-yl...)
Affinity DataIC50:  86nMAssay Description:Antagonist activity at MCHR1 assessed as inhibition of MCH-mediated calcium release in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207675(CHEMBL246464 | N-(1-(3-fluoro-4-(3-(piperidin-1-yl...)
Affinity DataIC50:  120nMAssay Description:Antagonist activity at MCHR1 assessed as inhibition of MCH-mediated calcium release in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207679(CHEMBL246258 | N-(1-(2-chloro-4-((2-(pyrrolidin-1-...)
Affinity DataIC50:  136nMAssay Description:Antagonist activity at MCHR1 assessed as inhibition of MCH-mediated calcium release in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207671(CHEMBL247688 | N-(1-(4-(3-methoxy-3-methylbutoxy)b...)
Affinity DataIC50:  165nMAssay Description:Displacement of [125I]MCH from MCHR1 expressed in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197123(CHEMBL214768 | N-(1-(3-fluoro-4-methoxybenzyl)pipe...)
Affinity DataIC50:  168nMAssay Description:Antagonist activity at MCHR1 assessed as inhibition of MCH-mediated calcium release in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207673(CHEMBL246259 | N-(1-(2-methoxy-4-((2-(pyrrolidin-1...)
Affinity DataIC50:  270nMAssay Description:Antagonist activity at MCHR1 assessed as inhibition of MCH-mediated calcium release in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207683(CHEMBL245846 | N-(1-(3-fluoro-4-((2-(pyrrolidin-1-...)
Affinity DataIC50:  420nMAssay Description:Antagonist activity at MCHR1 assessed as inhibition of MCH-mediated calcium release in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207685(CHEMBL394639 | N-(1-(3-fluoro-4-(2-(isobutoxyimino...)
Affinity DataIC50:  450nMAssay Description:Displacement of [3H]dofetilide from hERG expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207676(CHEMBL245642 | N-(1-(3-fluoro-4-(2-(methoxyimino)e...)
Affinity DataIC50:  480nMAssay Description:Antagonist activity at MCHR1 assessed as inhibition of MCH-mediated calcium release in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207684(CHEMBL246050 | N-(1-(4-((2-(piperidin-1-yl)ethyl)c...)
Affinity DataIC50:  519nMAssay Description:Antagonist activity at MCHR1 assessed as inhibition of MCH-mediated calcium release in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207674(CHEMBL245844 | N-(1-(4-(3-(2,4-dioxothiazolidin-3-...)
Affinity DataIC50:  545nMAssay Description:Antagonist activity at MCHR1 assessed as inhibition of MCH-mediated calcium release in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207678(CHEMBL247891 | N-(1-(4-(3-(dicyclopropylamino)prop...)
Affinity DataIC50:  740nMAssay Description:Displacement of [3H]dofetilide from hERG expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207677(CHEMBL248296 | N-(1-(4-(3-(dimethylamino)propoxy)-...)
Affinity DataIC50:  773nMAssay Description:Antagonist activity at MCHR1 assessed as inhibition of MCH-mediated calcium release in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207672(CHEMBL248295 | N-(1-(3-fluoro-4-(2-(pyrrolidin-1-y...)
Affinity DataIC50:  1.52E+3nMAssay Description:Displacement of [125I]MCH from MCHR1 expressed in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207687(CHEMBL247689 | N-(1-(3-fluoro-4-(2,2,2-trifluoroet...)
Affinity DataIC50:  1.60E+3nMAssay Description:Displacement of [3H]dofetilide from hERG expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207671(CHEMBL247688 | N-(1-(4-(3-methoxy-3-methylbutoxy)b...)
Affinity DataIC50:  1.75E+3nMAssay Description:Antagonist activity at MCHR1 assessed as inhibition of MCH-mediated calcium release in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207685(CHEMBL394639 | N-(1-(3-fluoro-4-(2-(isobutoxyimino...)
Affinity DataIC50:  1.98E+3nMAssay Description:Antagonist activity at MCHR1 assessed as inhibition of MCH-mediated calcium release in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207680(CHEMBL247283 | N-(1-(3-fluoro-4-(2-morpholinoethox...)
Affinity DataIC50: >2.00E+3nMAssay Description:Displacement of [125I]MCH from MCHR1 expressed in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207686(CHEMBL246051 | N-(1-(4-((2-(4,4-difluoropiperidin-...)
Affinity DataIC50:  2.93E+3nMAssay Description:Antagonist activity at MCHR1 assessed as inhibition of MCH-mediated calcium release in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207676(CHEMBL245642 | N-(1-(3-fluoro-4-(2-(methoxyimino)e...)
Affinity DataIC50:  3.20E+3nMAssay Description:Displacement of [3H]dofetilide from hERG expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207678(CHEMBL247891 | N-(1-(4-(3-(dicyclopropylamino)prop...)
Affinity DataIC50:  4.01E+3nMAssay Description:Antagonist activity at MCHR1 assessed as inhibition of MCH-mediated calcium release in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207671(CHEMBL247688 | N-(1-(4-(3-methoxy-3-methylbutoxy)b...)
Affinity DataIC50:  4.30E+3nMAssay Description:Displacement of [3H]dofetilide from hERG expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207686(CHEMBL246051 | N-(1-(4-((2-(4,4-difluoropiperidin-...)
Affinity DataIC50:  6.30E+3nMAssay Description:Displacement of [3H]dofetilide from hERG expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207673(CHEMBL246259 | N-(1-(2-methoxy-4-((2-(pyrrolidin-1...)
Affinity DataIC50:  6.60E+3nMAssay Description:Displacement of [3H]dofetilide from hERG expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197123(CHEMBL214768 | N-(1-(3-fluoro-4-methoxybenzyl)pipe...)
Affinity DataIC50:  8.30E+3nMAssay Description:Displacement of [3H]dofetilide from hERG expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207674(CHEMBL245844 | N-(1-(4-(3-(2,4-dioxothiazolidin-3-...)
Affinity DataIC50:  8.50E+3nMAssay Description:Displacement of [3H]dofetilide from hERG expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207675(CHEMBL246464 | N-(1-(3-fluoro-4-(3-(piperidin-1-yl...)
Affinity DataIC50:  9.18E+3nMAssay Description:Displacement of [3H]dofetilide from hERG expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207672(CHEMBL248295 | N-(1-(3-fluoro-4-(2-(pyrrolidin-1-y...)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at MCHR1 assessed as inhibition of MCH-mediated calcium release in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207679(CHEMBL246258 | N-(1-(2-chloro-4-((2-(pyrrolidin-1-...)
Affinity DataIC50:  1.10E+4nMAssay Description:Displacement of [3H]dofetilide from hERG expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197139(CHEMBL214021 | N-(1-(benzo[d][1,3]dioxol-5-ylmethy...)
Affinity DataIC50:  1.51E+4nMAssay Description:Displacement of [3H]dofetilide from hERG expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207682(CHEMBL247690 | N-(1-(3-fluoro-4-(3-morpholinopropo...)
Affinity DataIC50:  3.40E+4nMAssay Description:Displacement of [3H]dofetilide from hERG expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207681(CHEMBL248297 | N-(1-(3-fluoro-4-(3-(piperidin-1-yl...)
Affinity DataIC50:  4.20E+4nMAssay Description:Displacement of [3H]dofetilide from hERG expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207677(CHEMBL248296 | N-(1-(4-(3-(dimethylamino)propoxy)-...)
Affinity DataIC50:  6.50E+4nMAssay Description:Displacement of [3H]dofetilide from hERG expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207684(CHEMBL246050 | N-(1-(4-((2-(piperidin-1-yl)ethyl)c...)
Affinity DataIC50:  6.60E+4nMAssay Description:Displacement of [3H]dofetilide from hERG expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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