Compile Data Set for Download or QSAR
maximum 50k data
Found 46 Enz. Inhib. hit(s) with all data for entry = 50019851
TargetRho-associated protein kinase 2(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208318(1-(4-(1H-indazol-5-ylamino)piperidin-1-yl)-2-amino...)
Affinity DataIC50:  13nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208323(1-(4-(1H-indazol-5-ylamino)piperidin-1-yl)-2-(4-br...)
Affinity DataIC50:  80nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208321(1-(4-(1H-indazol-5-yl)piperazin-1-yl)-2-amino-2-(4...)
Affinity DataIC50:  90nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208322(1-(4-(1H-indazol-5-yl)piperazin-1-yl)-2-(4-bromoph...)
Affinity DataIC50:  100nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208325(1-(4-(1H-indazol-5-ylamino)piperidin-1-yl)-2-amino...)
Affinity DataIC50:  150nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208325(1-(4-(1H-indazol-5-ylamino)piperidin-1-yl)-2-amino...)
Affinity DataIC50:  170nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208329(1-(4-(1H-indazol-5-yl)piperazin-1-yl)-2-(4-chlorop...)
Affinity DataIC50:  190nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208338(1-(4-(1H-indazol-5-yl)piperazin-1-yl)-2-amino-2-(4...)
Affinity DataIC50:  190nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208320(1-(4-(1H-indazol-5-yl)piperazin-1-yl)-2-amino-2-(3...)
Affinity DataIC50:  250nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208334((S)-1-(4-(1H-indazol-5-ylamino)piperidin-1-yl)-2-(...)
Affinity DataIC50:  350nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208339((R)-1-(4-(1H-indazol-5-yl)piperazin-1-yl)-2-amino-...)
Affinity DataIC50:  380nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208321(1-(4-(1H-indazol-5-yl)piperazin-1-yl)-2-amino-2-(4...)
Affinity DataIC50:  410nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208326((S)-1-(4-(1H-indazol-5-ylamino)piperidin-1-yl)-2-a...)
Affinity DataIC50:  450nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208328((R)-1-(4-(1H-indazol-5-yl)piperazin-1-yl)-2-amino-...)
Affinity DataIC50:  470nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208330((S)-1-(4-(1H-indazol-5-ylamino)piperidin-1-yl)-2-a...)
Affinity DataIC50:  470nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208318(1-(4-(1H-indazol-5-ylamino)piperidin-1-yl)-2-amino...)
Affinity DataIC50:  490nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208338(1-(4-(1H-indazol-5-yl)piperazin-1-yl)-2-amino-2-(4...)
Affinity DataIC50:  530nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208320(1-(4-(1H-indazol-5-yl)piperazin-1-yl)-2-amino-2-(3...)
Affinity DataIC50:  760nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208337((R)-1-(4-(1H-indazol-5-ylamino)piperidin-1-yl)-2-h...)
Affinity DataIC50:  770nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208331((R)-1-(4-(1H-indazol-5-yl)piperazin-1-yl)-2-hydrox...)
Affinity DataIC50:  800nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208326((S)-1-(4-(1H-indazol-5-ylamino)piperidin-1-yl)-2-a...)
Affinity DataIC50:  830nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208336((R)-1-(4-(1H-indazol-5-yl)piperazin-1-yl)-2-(3-chl...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208330((S)-1-(4-(1H-indazol-5-ylamino)piperidin-1-yl)-2-a...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208317((S)-1-(4-(1H-indazol-5-ylamino)piperidin-1-yl)-2-h...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208337((R)-1-(4-(1H-indazol-5-ylamino)piperidin-1-yl)-2-h...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208335((R)-1-(4-(1H-indazol-5-yl)piperazin-1-yl)-2-(2-chl...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208328((R)-1-(4-(1H-indazol-5-yl)piperazin-1-yl)-2-amino-...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208319((S)-1-(4-(1H-indazol-5-ylamino)piperidin-1-yl)-2-(...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208334((S)-1-(4-(1H-indazol-5-ylamino)piperidin-1-yl)-2-(...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208329(1-(4-(1H-indazol-5-yl)piperazin-1-yl)-2-(4-chlorop...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208323(1-(4-(1H-indazol-5-ylamino)piperidin-1-yl)-2-(4-br...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208336((R)-1-(4-(1H-indazol-5-yl)piperazin-1-yl)-2-(3-chl...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208332((R)-1-(4-(1H-indazol-5-yl)piperazin-1-yl)-2-hydrox...)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208322(1-(4-(1H-indazol-5-yl)piperazin-1-yl)-2-(4-bromoph...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208319((S)-1-(4-(1H-indazol-5-ylamino)piperidin-1-yl)-2-(...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208333((S)-(4-(1H-indazol-5-yl)piperazin-1-yl)(1,2,3,4-te...)
Affinity DataIC50:  5.30E+3nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208324((S)-1-(4-(1H-indazol-5-ylamino)piperidin-1-yl)-2-a...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208339((R)-1-(4-(1H-indazol-5-yl)piperazin-1-yl)-2-amino-...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208335((R)-1-(4-(1H-indazol-5-yl)piperazin-1-yl)-2-(2-chl...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208332((R)-1-(4-(1H-indazol-5-yl)piperazin-1-yl)-2-hydrox...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208333((S)-(4-(1H-indazol-5-yl)piperazin-1-yl)(1,2,3,4-te...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208317((S)-1-(4-(1H-indazol-5-ylamino)piperidin-1-yl)-2-h...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208327((R)-1-(4-(1H-indazol-5-yl)piperazin-1-yl)-2-aminop...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208327((R)-1-(4-(1H-indazol-5-yl)piperazin-1-yl)-2-aminop...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208331((R)-1-(4-(1H-indazol-5-yl)piperazin-1-yl)-2-hydrox...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208324((S)-1-(4-(1H-indazol-5-ylamino)piperidin-1-yl)-2-a...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed