Compile Data Set for Download or QSAR
maximum 50k data
Found 53 Enz. Inhib. hit(s) with all data for entry = 50037911
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50211148((R)-N-(1-(4-oxo-3-(4-(prop-1-ynyl)phenyl)-3,4-dihy...)
Affinity DataIC50:  4nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50211114((-)-(R)-N-(1-(3-(4-ethoxyphenyl)-4-oxo-3,4-dihydro...)
Affinity DataIC50:  5nMAssay Description:Antagonist activity at human CXCR3 assessed as inhibition of ITAC-induced calcium mobilizationMore data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50211138((R)-N-(1-(3-(4-ethoxyphenyl)-4-oxo-3,4-dihydroquin...)
Affinity DataIC50:  6nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50211130((R)-N-(1-(3-(4-ethoxyphenyl)-4-oxo-3,4-dihydroquin...)
Affinity DataIC50:  6nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50211137((R)-N-(1-(3-(4-nitrophenyl)-4-oxo-3,4-dihydroquina...)
Affinity DataIC50:  7nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50211114((-)-(R)-N-(1-(3-(4-ethoxyphenyl)-4-oxo-3,4-dihydro...)
Affinity DataIC50:  8nMAssay Description:Inhibition of IP10-induced CXCR3 mediated cell migrationMore data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50211114((-)-(R)-N-(1-(3-(4-ethoxyphenyl)-4-oxo-3,4-dihydro...)
Affinity DataIC50:  8nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50211114((-)-(R)-N-(1-(3-(4-ethoxyphenyl)-4-oxo-3,4-dihydro...)
Affinity DataIC50:  8.20nMAssay Description:Displacement of [125I] ITAC from the CXCR3 receptorMore data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50211128(2-biphenyl-4-yl-N-(2-ethoxy-ethyl)-N-{(R)-1-[3-(4-...)
Affinity DataIC50:  9nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50211121((R)-N-(1-(3-(4-cyanophenyl)-4-oxo-3,4-dihydroquina...)
Affinity DataIC50:  11nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50211123((R)-N-(1-(3-(4-fluorophenyl)-4-oxo-3,4-dihydroquin...)
Affinity DataIC50:  12nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50211123((R)-N-(1-(3-(4-fluorophenyl)-4-oxo-3,4-dihydroquin...)
Affinity DataIC50:  13nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50211143((R)-N-(1-(3-(4-methoxyphenyl)-4-oxo-3,4-dihydroqui...)
Affinity DataIC50:  14nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50211114((-)-(R)-N-(1-(3-(4-ethoxyphenyl)-4-oxo-3,4-dihydro...)
Affinity DataIC50:  15nMAssay Description:Inhibition of ITAC-induced CXCR3 mediated cell migrationMore data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50211122((R)-N-(1-(3-(4-chlorophenyl)-4-oxo-3,4-dihydroquin...)
Affinity DataIC50:  22nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50211115((R)-N-(1-(4-oxo-3-p-tolyl-3,4-dihydroquinazolin-2-...)
Affinity DataIC50:  25nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50211114((-)-(R)-N-(1-(3-(4-ethoxyphenyl)-4-oxo-3,4-dihydro...)
Affinity DataIC50:  36nMAssay Description:Inhibition of MIG-induced CXCR3 mediated cell migrationMore data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50211119((R)-N-(2-ethoxyethyl)-N-(1-(3-(4-fluorophenyl)-4-o...)
Affinity DataIC50:  40nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50211118((R)-N-(1-(3-(4-fluorophenyl)-4-oxo-3,4-dihydroquin...)
Affinity DataIC50:  73nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50211156(2-biphenyl-4-yl-N-(2-dimethylamino-ethyl)-N-{(R)-1...)
Affinity DataIC50:  75nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50211132(2-biphenyl-4-yl-N-(2-ethoxy-ethyl)-N-{(R)-1-[3-(4-...)
Affinity DataIC50:  75nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50211117((R)-N-(2-(dimethylamino)ethyl)-N-(1-(3-(4-fluoroph...)
Affinity DataIC50:  88nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50211129((R)-N-(1-(3-(4-fluorophenyl)-4-oxo-3,4-dihydroquin...)
Affinity DataIC50:  100nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50211152((R)-N-(1-(3-(4-ethoxyphenyl)-4-oxo-3,4-dihydropyri...)
Affinity DataIC50:  144nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50211140((R)-N-(2-(dimethylamino)ethyl)-N-(1-(3-(4-fluoroph...)
Affinity DataIC50:  146nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50211151((R)-N-(2-(dimethylamino)ethyl)-N-(1-(3-(4-fluoroph...)
Affinity DataIC50:  154nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50211150((R)-N-(2-(dimethylamino)ethyl)-N-(1-(3-(4-fluoroph...)
Affinity DataIC50:  156nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50211145((R)-N-(2-(1H-imidazol-2-yl)-2-oxoethyl)-N-(1-(3-(4...)
Affinity DataIC50:  230nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50211144((R)-N-(1-(3-(4-fluorophenyl)-4-oxo-3,4-dihydroquin...)
Affinity DataIC50:  240nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50167778(CHEMBL194494 | Decanoic acid (2-dimethylamino-ethy...)
Affinity DataIC50:  250nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50211142((R)-N-(1-(4-oxo-3-phenyl-3,4-dihydroquinazolin-2-y...)
Affinity DataIC50:  299nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50211157((R)-N-(1-(3-(4-fluorophenyl)-4-oxo-3,4-dihydroquin...)
Affinity DataIC50:  300nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50211155((R)-N-(2-(dimethylamino)ethyl)-N-(1-(3-(4-fluoroph...)
Affinity DataIC50:  375nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50211147((R)-N-(1-(3-(4-ethoxyphenyl)-4-oxo-3,4-dihydropter...)
Affinity DataIC50:  480nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50167778(CHEMBL194494 | Decanoic acid (2-dimethylamino-ethy...)
Affinity DataIC50:  500nMAssay Description:Antagonist activity at human CXCR3 assessed as inhibition of MIG-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50211120((R)-N-(2-(dimethylamino)ethyl)-N-(1-(3-(4-fluoroph...)
Affinity DataIC50:  587nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50211153((R)-N-(2-(1H-imidazol-4-yl)-2-oxoethyl)-N-(1-(3-(4...)
Affinity DataIC50:  650nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50211134((R)-2-(1-((2-(dimethylamino)ethyl)(nonyl)amino)eth...)
Affinity DataIC50:  710nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50211125((R)-2-(1-((2-(dimethylamino)ethyl)(octyl)amino)eth...)
Affinity DataIC50:  790nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50211154((R)-4-(4-oxo-2-(1-(N-(pyridin-3-ylmethyl)-2-(4-(tr...)
Affinity DataIC50:  1.37E+3nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50211136((R)-N-(1-(3-(4-ethoxyphenyl)-4-oxo-3,4-dihydropyri...)
Affinity DataIC50:  1.40E+3nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50211149((R)-N-(2-(dimethylamino)ethyl)-N-(1-(3-(4-fluoroph...)
Affinity DataIC50:  1.40E+3nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50211135(2-biphenyl-4-yl-N-(2-ethoxy-ethyl)-N-[3-(4-ethoxy-...)
Affinity DataIC50:  2.30E+3nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50211146(2-biphenyl-4-yl-N-(2-ethoxy-ethyl)-N-{(R)-[3-(4-et...)
Affinity DataIC50:  4.00E+3nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50211126((R)-N-(2-(dimethylamino)ethyl)-N-(1-(3-(4-fluoroph...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50211139(CHEMBL395771 | biphenyl-4-carboxylic acid (2-dimet...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50211116((R)-N-(2-(dimethylamino)ethyl)-N-(1-(3-(4-fluoroph...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50211133((R)-N-(1-(3-(4-(methylsulfonyl)phenyl)-4-oxo-3,4-d...)
Affinity DataIC50:  1.00E+4nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50211131(2-biphenyl-4-yl-N-(2-ethoxy-ethyl)-N-{1-[3-(4-etho...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50211158((R)-N-(2-(dimethylamino)ethyl)-N-(1-(3-(4-fluoroph...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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