Compile Data Set for Download or QSAR
maximum 50k data
Found 4 Enz. Inhib. hit(s) with all data for entry = 50025226
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50270005(5'-(N-ethyl-N-isopropyl)amiloride | CHEMBL1909809 ...)
Affinity DataIC50:  800nMAssay Description:Inhibition of human wild type NHE1 expressed in chinese hamster AP1 cells assessed as intracellular pHi recovery by ammonium chloride prepulse protoc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger(Amphiuma tridactylum)
University Of California

Curated by ChEMBL
LigandPNGBDBM50270005(5'-(N-ethyl-N-isopropyl)amiloride | CHEMBL1909809 ...)
Affinity DataIC50:  8.70E+3nMAssay Description:Inhibition of Amphiuma tridactylum wild type NHE1 expressed in chinese hamster AP1 cells assessed as intracellular pHi recovery by ammonium chloride ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM16173(3,5-diamino-6-chloro-N-(diaminomethylene)pyrazinam...)
Affinity DataIC50:  6.00E+4nMAssay Description:Inhibition of human wild type NHE1 expressed in chinese hamster AP1 cells assessed as intracellular pHi recovery by ammonium chloride prepulse protoc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger(Amphiuma tridactylum)
University Of California

Curated by ChEMBL
LigandPNGBDBM16173(3,5-diamino-6-chloro-N-(diaminomethylene)pyrazinam...)
Affinity DataIC50:  9.80E+4nMAssay Description:Inhibition of Amphiuma tridactylum wild type NHE1 expressed in chinese hamster AP1 cells assessed as intracellular pHi recovery by ammonium chloride ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed