Compile Data Set for Download or QSAR
maximum 50k data
Found 22 Enz. Inhib. hit(s) with all data for entry = 50020751
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
University Of Vienna

Curated by ChEMBL
LigandPNGBDBM50217120(1,2-dihydro-7-methoxy-3-(2,3,4-trimethoxyphenyl)-n...)
Affinity DataIC50:  15nMAssay Description:Inhibition of ovine COX1 by measuring PGE2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
University Of Vienna

Curated by ChEMBL
LigandPNGBDBM50217117(2-(2,3,4-trimethoxyphenyl)-1H-indene | CHEMBL22856...)
Affinity DataIC50:  30nMAssay Description:Inhibition of ovine COX1 by measuring PGE2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Vienna

Curated by ChEMBL
LigandPNGBDBM50217121(1,2-dihydro-3-(3,4-dimethoxyphenyl)-7-methoxynapht...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human recombinant COX2 by measuring PGE2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Vienna

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  35nMAssay Description:Inhibition of human recombinant COX2 by measuring PGE2More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
University Of Vienna

Curated by ChEMBL
LigandPNGBDBM50217121(1,2-dihydro-3-(3,4-dimethoxyphenyl)-7-methoxynapht...)
Affinity DataIC50:  380nMAssay Description:Inhibition of ovine COX1 by measuring PGE2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
University Of Vienna

Curated by ChEMBL
LigandPNGBDBM50217115(2-(2-methoxyphenyl)-1H-indene | CHEMBL376583)
Affinity DataIC50:  460nMAssay Description:Inhibition of ovine COX1 by measuring PGE2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
University Of Vienna

Curated by ChEMBL
LigandPNGBDBM50217119(1,2-dihydro-3-(2,3,4-trimethoxyphenyl)naphthalene ...)
Affinity DataIC50:  480nMAssay Description:Inhibition of ovine COX1 by measuring PGE2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
University Of Vienna

Curated by ChEMBL
LigandPNGBDBM23926((E)-resveratrol | 5-[(E)-2-(4-hydroxyphenyl)etheny...)
Affinity DataIC50:  535nMAssay Description:Inhibition of ovine COX1 by measuring PGE2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Vienna

Curated by ChEMBL
LigandPNGBDBM50217119(1,2-dihydro-3-(2,3,4-trimethoxyphenyl)naphthalene ...)
Affinity DataIC50:  660nMAssay Description:Inhibition of human recombinant COX2 by measuring PGE2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Vienna

Curated by ChEMBL
LigandPNGBDBM23926((E)-resveratrol | 5-[(E)-2-(4-hydroxyphenyl)etheny...)
Affinity DataIC50:  996nMAssay Description:Inhibition of human recombinant COX2 by measuring PGE2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Vienna

Curated by ChEMBL
LigandPNGBDBM50217117(2-(2,3,4-trimethoxyphenyl)-1H-indene | CHEMBL22856...)
Affinity DataIC50:  1.33E+3nMAssay Description:Inhibition of human recombinant COX2 by measuring PGE2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
University Of Vienna

Curated by ChEMBL
LigandPNGBDBM50217118(5-(2-1H-indenyl)-1,3-benzodioxole | CHEMBL229139)
Affinity DataIC50:  1.28E+4nMAssay Description:Inhibition of ovine COX1 by measuring PGE2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
University Of Vienna

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of ovine COX1 by measuring PGE2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
University Of Vienna

Curated by ChEMBL
LigandPNGBDBM50217116(1,2-dihydro-3-(3,4-dimethoxyphenyl)naphthalene | C...)
Affinity DataIC50:  6.11E+4nMAssay Description:Inhibition of ovine COX1 by measuring PGE2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Vienna

Curated by ChEMBL
LigandPNGBDBM50217115(2-(2-methoxyphenyl)-1H-indene | CHEMBL376583)
Affinity DataIC50:  6.23E+4nMAssay Description:Inhibition of human recombinant COX2 by measuring PGE2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
University Of Vienna

Curated by ChEMBL
LigandPNGBDBM22360(2-(acetyloxy)benzoate | 2-(acetyloxy)benzoic acid ...)
Affinity DataIC50:  9.00E+4nMAssay Description:Inhibition of ovine COX1 by measuring PGE2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Vienna

Curated by ChEMBL
LigandPNGBDBM50217122(5-(1,2-dihydro-3-naphthalenyl)-1,3-benzodioxole | ...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant COX2 by measuring PGE2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Vienna

Curated by ChEMBL
LigandPNGBDBM50217116(1,2-dihydro-3-(3,4-dimethoxyphenyl)naphthalene | C...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant COX2 by measuring PGE2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Vienna

Curated by ChEMBL
LigandPNGBDBM50217118(5-(2-1H-indenyl)-1,3-benzodioxole | CHEMBL229139)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant COX2 by measuring PGE2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
University Of Vienna

Curated by ChEMBL
LigandPNGBDBM50217122(5-(1,2-dihydro-3-naphthalenyl)-1,3-benzodioxole | ...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of ovine COX1 by measuring PGE2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Vienna

Curated by ChEMBL
LigandPNGBDBM22360(2-(acetyloxy)benzoate | 2-(acetyloxy)benzoic acid ...)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of human recombinant COX2 by measuring PGE2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Vienna

Curated by ChEMBL
LigandPNGBDBM50217120(1,2-dihydro-7-methoxy-3-(2,3,4-trimethoxyphenyl)-n...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant COX2 by measuring PGE2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed