Compile Data Set for Download or QSAR
maximum 50k data
Found 36 Enz. Inhib. hit(s) with all data for entry = 50020825
TargetCytochrome P450 2C9(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50218042(6-((4-(2-(2-methylquinolin-5-yloxy)ethyl)piperazin...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50218034(4-butyl-6-((4-(2-(2-methylquinolin-5-yloxy)ethyl)p...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50218042(6-((4-(2-(2-methylquinolin-5-yloxy)ethyl)piperazin...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50218039(4-benzyl-6-((4-(2-(2-methylquinolin-5-yloxy)ethyl)...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50218037(4-ethyl-5-fluoro-6-((4-(2-(2-methylquinolin-5-ylox...)
Affinity DataIC50: >9.00E+3nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50218037(4-ethyl-5-fluoro-6-((4-(2-(2-methylquinolin-5-ylox...)
Affinity DataIC50: >9.00E+3nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50218037(4-ethyl-5-fluoro-6-((4-(2-(2-methylquinolin-5-ylox...)
Affinity DataIC50: >9.00E+3nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50218037(4-ethyl-5-fluoro-6-((4-(2-(2-methylquinolin-5-ylox...)
Affinity DataIC50: >9.00E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50218042(6-((4-(2-(2-methylquinolin-5-yloxy)ethyl)piperazin...)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50218037(4-ethyl-5-fluoro-6-((4-(2-(2-methylquinolin-5-ylox...)
Affinity DataIC50: >9.00E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50218039(4-benzyl-6-((4-(2-(2-methylquinolin-5-yloxy)ethyl)...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50218039(4-benzyl-6-((4-(2-(2-methylquinolin-5-yloxy)ethyl)...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50218039(4-benzyl-6-((4-(2-(2-methylquinolin-5-yloxy)ethyl)...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50218034(4-butyl-6-((4-(2-(2-methylquinolin-5-yloxy)ethyl)p...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50218042(6-((4-(2-(2-methylquinolin-5-yloxy)ethyl)piperazin...)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50218041(4-ethyl-6-((4-(2-(2-methylquinolin-5-yloxy)ethyl)p...)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50218039(4-benzyl-6-((4-(2-(2-methylquinolin-5-yloxy)ethyl)...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50218036(5-fluoro-4-methyl-6-((4-(2-(2-methylquinolin-5-ylo...)
Affinity DataIC50: >1.60E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50218034(4-butyl-6-((4-(2-(2-methylquinolin-5-yloxy)ethyl)p...)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50218036(5-fluoro-4-methyl-6-((4-(2-(2-methylquinolin-5-ylo...)
Affinity DataIC50: >1.60E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50218036(5-fluoro-4-methyl-6-((4-(2-(2-methylquinolin-5-ylo...)
Affinity DataIC50: >1.60E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50218036(5-fluoro-4-methyl-6-((4-(2-(2-methylquinolin-5-ylo...)
Affinity DataIC50: >1.60E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50218036(5-fluoro-4-methyl-6-((4-(2-(2-methylquinolin-5-ylo...)
Affinity DataIC50: >1.60E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50218042(6-((4-(2-(2-methylquinolin-5-yloxy)ethyl)piperazin...)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50218038(6-((4-(2-(2-methylquinolin-5-yloxy)ethyl)piperazin...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50218041(4-ethyl-6-((4-(2-(2-methylquinolin-5-yloxy)ethyl)p...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50218035(8-fluoro-4-methyl-6-((4-(2-(2-methylquinolin-5-ylo...)
Affinity DataIC50: >1.90E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50218035(8-fluoro-4-methyl-6-((4-(2-(2-methylquinolin-5-ylo...)
Affinity DataIC50: >1.90E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50218035(8-fluoro-4-methyl-6-((4-(2-(2-methylquinolin-5-ylo...)
Affinity DataIC50: >1.90E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50218035(8-fluoro-4-methyl-6-((4-(2-(2-methylquinolin-5-ylo...)
Affinity DataIC50: >1.90E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50218035(8-fluoro-4-methyl-6-((4-(2-(2-methylquinolin-5-ylo...)
Affinity DataIC50: >1.90E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50218040(4-methyl-6-((4-(2-(2-methylquinolin-5-yloxy)ethyl)...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50218040(4-methyl-6-((4-(2-(2-methylquinolin-5-yloxy)ethyl)...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50218040(4-methyl-6-((4-(2-(2-methylquinolin-5-yloxy)ethyl)...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50218040(4-methyl-6-((4-(2-(2-methylquinolin-5-yloxy)ethyl)...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50218040(4-methyl-6-((4-(2-(2-methylquinolin-5-yloxy)ethyl)...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed