Compile Data Set for Download or QSAR
maximum 50k data
Found 18 Enz. Inhib. hit(s) with all data for entry = 50038043
TargetProgesterone receptor(Homo sapiens (Human))
Rti International

Curated by ChEMBL
LigandPNGBDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
Affinity DataIC50:  0.0540nMAssay Description:Antagonist activity at progesterone receptor expressed in human T47D cells assessed as inhibition of promegestone-induced alkaline phosphatase activi...More data for this Ligand-Target Pair
TargetProgesterone receptor(Homo sapiens (Human))
Rti International

Curated by ChEMBL
LigandPNGBDBM50222089((3S,10'S,11'S,15'S,17'R)-17'-(4-acetylphenyl)-5-et...)
Affinity DataIC50:  0.340nMAssay Description:Antagonist activity at progesterone receptor expressed in human T47D cells assessed as inhibition of promegestone-induced alkaline phosphatase activi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Rti International

Curated by ChEMBL
LigandPNGBDBM50222091((3S,10'S,11'S,15'S,17'R)-17'-(4-acetylphenyl)-5,15...)
Affinity DataIC50:  0.590nMAssay Description:Antagonist activity at progesterone receptor expressed in human T47D cells assessed as inhibition of promegestone-induced alkaline phosphatase activi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Rti International

Curated by ChEMBL
LigandPNGBDBM50222086((3S,10'S,11'S,15'S,17'R)-17'-[4-(dimethylamino)phe...)
Affinity DataIC50:  0.630nMAssay Description:Antagonist activity at progesterone receptor expressed in human T47D cells assessed as inhibition of promegestone-induced alkaline phosphatase activi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Rti International

Curated by ChEMBL
LigandPNGBDBM50222092((3S,10'S,11'S,15'S,17'R)-17'-[4-(dimethylamino)phe...)
Affinity DataIC50:  0.980nMAssay Description:Antagonist activity at progesterone receptor expressed in human T47D cells assessed as inhibition of promegestone-induced alkaline phosphatase activi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Rti International

Curated by ChEMBL
LigandPNGBDBM50222088((3S,10'S,11'S,15'S,17'R)-5-ethyl-17'-(3-fluoro-4-m...)
Affinity DataIC50:  1nMAssay Description:Antagonist activity at progesterone receptor expressed in human T47D cells assessed as inhibition of promegestone-induced alkaline phosphatase activi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Rti International

Curated by ChEMBL
LigandPNGBDBM50222087((3S,10'S,11'S,15'S,17'R)-17'-(3-fluoro-4-methoxyph...)
Affinity DataIC50:  4.60nMAssay Description:Antagonist activity at progesterone receptor expressed in human T47D cells assessed as inhibition of promegestone-induced alkaline phosphatase activi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Rti International

Curated by ChEMBL
LigandPNGBDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
Affinity DataIC50:  6nMAssay Description:Antagonist activity at glucocorticoid receptor expressed in A549 cells assessed as inhibition of corticoid-induced gene transcription by luciferase r...More data for this Ligand-Target Pair
TargetProgesterone receptor(Homo sapiens (Human))
Rti International

Curated by ChEMBL
LigandPNGBDBM50222085((3S,10'S,11'S,15'S,17'R)-17'-[4-(dimethylamino)phe...)
Affinity DataIC50:  18nMAssay Description:Antagonist activity at progesterone receptor expressed in human T47D cells assessed as inhibition of promegestone-induced alkaline phosphatase activi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Rti International

Curated by ChEMBL
LigandPNGBDBM50222092((3S,10'S,11'S,15'S,17'R)-17'-[4-(dimethylamino)phe...)
Affinity DataIC50:  23nMAssay Description:Antagonist activity at glucocorticoid receptor expressed in A549 cells assessed as inhibition of corticoid-induced gene transcription by luciferase r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Rti International

Curated by ChEMBL
LigandPNGBDBM50222086((3S,10'S,11'S,15'S,17'R)-17'-[4-(dimethylamino)phe...)
Affinity DataIC50:  82nMAssay Description:Antagonist activity at glucocorticoid receptor expressed in A549 cells assessed as inhibition of corticoid-induced gene transcription by luciferase r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Rti International

Curated by ChEMBL
LigandPNGBDBM50222090((3S,10'S,11'S,15'S,17'R)-17'-(4-acetylphenyl)-15'-...)
Affinity DataIC50:  82nMAssay Description:Antagonist activity at progesterone receptor expressed in human T47D cells assessed as inhibition of promegestone-induced alkaline phosphatase activi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Rti International

Curated by ChEMBL
LigandPNGBDBM50222089((3S,10'S,11'S,15'S,17'R)-17'-(4-acetylphenyl)-5-et...)
Affinity DataIC50:  210nMAssay Description:Antagonist activity at glucocorticoid receptor expressed in A549 cells assessed as inhibition of corticoid-induced gene transcription by luciferase r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Rti International

Curated by ChEMBL
LigandPNGBDBM50222091((3S,10'S,11'S,15'S,17'R)-17'-(4-acetylphenyl)-5,15...)
Affinity DataIC50:  460nMAssay Description:Antagonist activity at glucocorticoid receptor expressed in A549 cells assessed as inhibition of corticoid-induced gene transcription by luciferase r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Rti International

Curated by ChEMBL
LigandPNGBDBM50222085((3S,10'S,11'S,15'S,17'R)-17'-[4-(dimethylamino)phe...)
Affinity DataIC50:  540nMAssay Description:Antagonist activity at glucocorticoid receptor expressed in A549 cells assessed as inhibition of corticoid-induced gene transcription by luciferase r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Rti International

Curated by ChEMBL
LigandPNGBDBM50222087((3S,10'S,11'S,15'S,17'R)-17'-(3-fluoro-4-methoxyph...)
Affinity DataIC50:  660nMAssay Description:Antagonist activity at glucocorticoid receptor expressed in A549 cells assessed as inhibition of corticoid-induced gene transcription by luciferase r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Rti International

Curated by ChEMBL
LigandPNGBDBM50222088((3S,10'S,11'S,15'S,17'R)-5-ethyl-17'-(3-fluoro-4-m...)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at glucocorticoid receptor expressed in A549 cells assessed as inhibition of corticoid-induced gene transcription by luciferase r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Rti International

Curated by ChEMBL
LigandPNGBDBM50222090((3S,10'S,11'S,15'S,17'R)-17'-(4-acetylphenyl)-15'-...)
Affinity DataIC50:  1.40E+4nMAssay Description:Antagonist activity at glucocorticoid receptor expressed in A549 cells assessed as inhibition of corticoid-induced gene transcription by luciferase r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed