Compile Data Set for Download or QSAR
maximum 50k data
Found 46 Enz. Inhib. hit(s) with all data for entry = 50021279
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50206613(3-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-benzo...)
Affinity DataIC50:  350nMAssay Description:Inhibition of hypoxia induced HIF1alpha transcriptional activity in human AGS cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50206613(3-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-benzo...)
Affinity DataIC50:  400nMAssay Description:Inhibition of hypoxia induced HIF1alpha transcriptional activity in human Hep3B cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50222818(2-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-isoni...)
Affinity DataIC50:  600nMAssay Description:Inhibition of hypoxia induced HIF1alpha transcriptional activity in human Sk-Hep1 cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50206600(3-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-benzo...)
Affinity DataIC50:  700nMAssay Description:Inhibition of hypoxia induced HIF1alpha transcriptional activity in human AGS cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50222823(2-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-isoni...)
Affinity DataIC50:  800nMAssay Description:Inhibition of hypoxia induced HIF1alpha transcriptional activity in human AGS cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50222815(5-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-nicot...)
Affinity DataIC50:  900nMAssay Description:Inhibition of hypoxia induced HIF1alpha transcriptional activity in human AGS cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50222820(2-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-N-(3-...)
Affinity DataIC50:  900nMAssay Description:Inhibition of hypoxia induced HIF1alpha transcriptional activity in human Sk-Hep1 cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50222823(2-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-isoni...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of hypoxia induced HIF1alpha transcriptional activity in human Hep3B cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50222824(2-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-isoni...)
Affinity DataIC50:  1.03E+3nMAssay Description:Inhibition of hypoxia induced HIF1alpha transcriptional activity in human Sk-Hep1 cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50222824(2-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-isoni...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of hypoxia induced HIF1alpha transcriptional activity in human Hep3B cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50222817(5-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-N-(2-...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of hypoxia induced HIF1alpha transcriptional activity in human AGS cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50222818(2-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-isoni...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of hypoxia induced HIF1alpha transcriptional activity in human AGS cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50222827(5-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-N-(3-...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of hypoxia induced HIF1alpha transcriptional activity in human Sk-Hep1 cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50222824(2-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-isoni...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of hypoxia induced HIF1alpha transcriptional activity in human AGS cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50095469((5-(1-benzyl-1H-indazol-3-yl)furan-2-yl)methanol |...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of hypoxia induced HIF1alpha transcriptional activity in human AGS cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50222823(2-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-isoni...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of hypoxia induced HIF1alpha transcriptional activity in human Sk-Hep1 cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50222821(2-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-N-(4-...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of hypoxia induced HIF1alpha transcriptional activity in human Sk-Hep1 cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50206600(3-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-benzo...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of hypoxia induced HIF1alpha transcriptional activity in human Hep3B cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50222818(2-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-isoni...)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of hypoxia induced HIF1alpha transcriptional activity in human Hep3B cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50222825(2-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-N-(2-...)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of hypoxia induced HIF1alpha transcriptional activity in human Hep3B cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50222825(2-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-N-(2-...)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of hypoxia induced HIF1alpha transcriptional activity in human Sk-Hep1 cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50222826(5-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-N-fur...)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of hypoxia induced HIF1alpha transcriptional activity in human Sk-Hep1 cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50222822(5-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-nicot...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of hypoxia induced HIF1alpha transcriptional activity in human AGS cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50222825(2-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-N-(2-...)
Affinity DataIC50:  5.20E+3nMAssay Description:Inhibition of hypoxia induced HIF1alpha transcriptional activity in human AGS cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50222822(5-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-nicot...)
Affinity DataIC50:  5.90E+3nMAssay Description:Inhibition of hypoxia induced HIF1alpha transcriptional activity in human Hep3B cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50222827(5-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-N-(3-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of hypoxia induced HIF1alpha transcriptional activity in human AGS cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50222827(5-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-N-(3-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of hypoxia induced HIF1alpha transcriptional activity in human Hep3B cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50222815(5-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-nicot...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of hypoxia induced HIF1alpha transcriptional activity in human Hep3B cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50222820(2-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-N-(3-...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of hypoxia induced HIF1alpha transcriptional activity in human AGS cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50222820(2-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-N-(3-...)
Affinity DataIC50:  1.12E+4nMAssay Description:Inhibition of hypoxia induced HIF1alpha transcriptional activity in human Hep3B cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50222815(5-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-nicot...)
Affinity DataIC50:  1.19E+4nMAssay Description:Inhibition of hypoxia induced HIF1alpha transcriptional activity in human Sk-Hep1 cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50095469((5-(1-benzyl-1H-indazol-3-yl)furan-2-yl)methanol |...)
Affinity DataIC50:  1.38E+4nMAssay Description:Inhibition of hypoxia induced HIF1alpha transcriptional activity in human Hep3B cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50222821(2-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-N-(4-...)
Affinity DataIC50:  1.86E+4nMAssay Description:Inhibition of hypoxia induced HIF1alpha transcriptional activity in human AGS cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50222817(5-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-N-(2-...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of hypoxia induced HIF1alpha transcriptional activity in human Hep3B cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50222822(5-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-nicot...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of hypoxia induced HIF1alpha transcriptional activity in human Sk-Hep1 cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50222826(5-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-N-fur...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of hypoxia induced HIF1alpha transcriptional activity in human AGS cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50222816(5-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-nicot...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of hypoxia induced HIF1alpha transcriptional activity in human Hep3B cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50222819(2-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-N-fur...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of hypoxia induced HIF1alpha transcriptional activity in human AGS cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50222819(2-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-N-fur...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of hypoxia induced HIF1alpha transcriptional activity in human Hep3B cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50222817(5-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-N-(2-...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of hypoxia induced HIF1alpha transcriptional activity in human Sk-Hep1 cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50222821(2-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-N-(4-...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of hypoxia induced HIF1alpha transcriptional activity in human Hep3B cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50222819(2-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-N-fur...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of hypoxia induced HIF1alpha transcriptional activity in human Sk-Hep1 cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50222816(5-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-nicot...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of hypoxia induced HIF1alpha transcriptional activity in human Sk-Hep1 cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50222816(5-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-nicot...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of hypoxia induced HIF1alpha transcriptional activity in human AGS cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50222826(5-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-N-fur...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of hypoxia induced HIF1alpha transcriptional activity in human Hep3B cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50095469((5-(1-benzyl-1H-indazol-3-yl)furan-2-yl)methanol |...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of hypoxia induced HIF1alpha transcriptional activity in human Sk-Hep1 cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed