Compile Data Set for Download or QSAR
maximum 50k data
Found 23 Enz. Inhib. hit(s) with all data for entry = 50021304
TargetCaspase-8(Homo sapiens (Human))
Epicept

Curated by ChEMBL
LigandPNGBDBM50223100(2-(2-((S)-2-(benzyloxycarbonyl)-3-methylbutanamido...)
Affinity DataIC50:  6nMAssay Description:Inhibition of human caspase 8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-9(Homo sapiens (Human))
Epicept

Curated by ChEMBL
LigandPNGBDBM50223100(2-(2-((S)-2-(benzyloxycarbonyl)-3-methylbutanamido...)
Affinity DataIC50:  6nMAssay Description:Inhibition of human caspase 9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-7(Homo sapiens (Human))
Epicept

Curated by ChEMBL
LigandPNGBDBM50223100(2-(2-((S)-2-(benzyloxycarbonyl)-3-methylbutanamido...)
Affinity DataIC50:  11nMAssay Description:Inhibition of human caspase 7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Epicept

Curated by ChEMBL
LigandPNGBDBM50223100(2-(2-((S)-2-(benzyloxycarbonyl)-3-methylbutanamido...)
Affinity DataIC50:  12nMAssay Description:Inhibition of human caspase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Epicept

Curated by ChEMBL
LigandPNGBDBM50223100(2-(2-((S)-2-(benzyloxycarbonyl)-3-methylbutanamido...)
Affinity DataIC50:  33nMAssay Description:Inhibition of human recombinant caspase 3 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-6(Homo sapiens (Human))
Epicept

Curated by ChEMBL
LigandPNGBDBM50223100(2-(2-((S)-2-(benzyloxycarbonyl)-3-methylbutanamido...)
Affinity DataIC50:  61nMAssay Description:Inhibition of human caspase 6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Epicept

Curated by ChEMBL
LigandPNGBDBM50223106((R)-2-(1-(benzyloxycarbonyl)-N-(2-fluoroacetyl)aze...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human recombinant caspase 3 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Epicept

Curated by ChEMBL
LigandPNGBDBM50223110(3-(3-(benzyloxycarbonyl)thiophene-2-carboxamido)-5...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human recombinant caspase 3 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Epicept

Curated by ChEMBL
LigandPNGBDBM50223108(3-(2-(benzyloxycarbonyl)benzamido)-5-fluoro-4-oxop...)
Affinity DataIC50:  200nMAssay Description:Inhibition of human recombinant caspase 3 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Epicept

Curated by ChEMBL
LigandPNGBDBM50223115(3-((1S,2R)-2-(benzyloxycarbonyl)cyclopentanecarbox...)
Affinity DataIC50:  210nMAssay Description:Inhibition of human recombinant caspase 3 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Epicept

Curated by ChEMBL
LigandPNGBDBM50223112(3-((1S,2R)-2-(benzyloxycarbonyl)cyclohexanecarboxa...)
Affinity DataIC50:  250nMAssay Description:Inhibition of human recombinant caspase 3 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Epicept

Curated by ChEMBL
LigandPNGBDBM50223102(3-(2-(benzyloxycarbonyl)-5-methylbenzamido)-5-fluo...)
Affinity DataIC50:  260nMAssay Description:Inhibition of human recombinant caspase 3 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Epicept

Curated by ChEMBL
LigandPNGBDBM50223101(3-(2-(benzyloxycarbonyl)-5-fluorobenzamido)-5-fluo...)
Affinity DataIC50:  270nMAssay Description:Inhibition of human recombinant caspase 3 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Epicept

Curated by ChEMBL
LigandPNGBDBM50223107(3-(2-(benzyloxycarbonyl)-5-chlorobenzamido)-5-fluo...)
Affinity DataIC50:  320nMAssay Description:Inhibition of human recombinant caspase 3 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Epicept

Curated by ChEMBL
LigandPNGBDBM50223111(3-[2-((S)-2-benzyloxycarbonylamino-4-carboxy-butyr...)
Affinity DataIC50:  340nMAssay Description:Inhibition of human recombinant caspase 3 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Epicept

Curated by ChEMBL
LigandPNGBDBM50223104((R)-2-(1-(benzyloxycarbonyl)-N-(2-fluoroacetyl)pyr...)
Affinity DataIC50:  410nMAssay Description:Inhibition of human recombinant caspase 3 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Epicept

Curated by ChEMBL
LigandPNGBDBM50223117(3-(2-(benzyloxycarbonyl)-6-chlorobenzamido)-5-fluo...)
Affinity DataIC50:  450nMAssay Description:Inhibition of human recombinant caspase 3 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Epicept

Curated by ChEMBL
LigandPNGBDBM50223113(3-(2-(benzyloxycarbonyl)-4-chlorobenzamido)-5-fluo...)
Affinity DataIC50:  550nMAssay Description:Inhibition of human recombinant caspase 3 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Epicept

Curated by ChEMBL
LigandPNGBDBM50223116(3-(2-(benzyloxycarbonyl)-3-methylbenzamido)-5-fluo...)
Affinity DataIC50:  720nMAssay Description:Inhibition of human recombinant caspase 3 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Epicept

Curated by ChEMBL
LigandPNGBDBM50223109(3-(2-(benzyloxycarbonyl)-6-methylbenzamido)-5-fluo...)
Affinity DataIC50:  860nMAssay Description:Inhibition of human recombinant caspase 3 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Epicept

Curated by ChEMBL
LigandPNGBDBM50223114(3-(2-(benzyloxycarbonyl)-3,5-dimethylbenzamido)-5-...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of human recombinant caspase 3 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Epicept

Curated by ChEMBL
LigandPNGBDBM50223105(3-((1S,2S)-2-(benzyloxycarbonyl)cyclohexanecarboxa...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of human recombinant caspase 3 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Epicept

Curated by ChEMBL
LigandPNGBDBM50223103(3-(2-(benzyloxycarbonyl)-3-methoxybenzamido)-5-flu...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of human recombinant caspase 3 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed