Compile Data Set for Download or QSAR
maximum 50k data
Found 21 Enz. Inhib. hit(s) with all data for entry = 50021341
TargetHistone deacetylase 4(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering

Curated by ChEMBL
LigandPNGBDBM50222732((5S,11S,13aR)-5-benzyl-8,8-dimethyl-11-[5-(pyridin...)
Affinity DataIC50:  18nMAssay Description:Inhibition of HDAC4 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering

Curated by ChEMBL
LigandPNGBDBM50223507((1R,14S,20R,23S)-23-[5-(Pyridin-2-yldisulfanyl)-pe...)
Affinity DataIC50:  20nMAssay Description:Inhibition of HDAC4 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering

Curated by ChEMBL
LigandPNGBDBM50223505((5S,11S,13aR)-5-((S)-sec-butyl)-8,8-dimethyl-11-[5...)
Affinity DataIC50:  23nMAssay Description:Inhibition of HDAC4 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering

Curated by ChEMBL
LigandPNGBDBM50223506((5S,11S,13aR)-5-butyl-8,8-dimethyl-11-[5-(pyridin-...)
Affinity DataIC50:  24nMAssay Description:Inhibition of HDAC4 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering

Curated by ChEMBL
LigandPNGBDBM50223504((5S,11S,13aR)-5-isobutyl-8,8-dimethyl-11-[5-(pyrid...)
Affinity DataIC50:  33nMAssay Description:Inhibition of HDAC4 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering

Curated by ChEMBL
LigandPNGBDBM50223507((1R,14S,20R,23S)-23-[5-(Pyridin-2-yldisulfanyl)-pe...)
Affinity DataIC50:  35nMAssay Description:Inhibition of HDAC1 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering

Curated by ChEMBL
LigandPNGBDBM50223505((5S,11S,13aR)-5-((S)-sec-butyl)-8,8-dimethyl-11-[5...)
Affinity DataIC50:  38nMAssay Description:Inhibition of HDAC1 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering

Curated by ChEMBL
LigandPNGBDBM50223506((5S,11S,13aR)-5-butyl-8,8-dimethyl-11-[5-(pyridin-...)
Affinity DataIC50:  38nMAssay Description:Inhibition of HDAC1 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering

Curated by ChEMBL
LigandPNGBDBM50222732((5S,11S,13aR)-5-benzyl-8,8-dimethyl-11-[5-(pyridin...)
Affinity DataIC50:  39nMAssay Description:Inhibition of HDAC1 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering

Curated by ChEMBL
LigandPNGBDBM50222727((5S,11S,13aR)-5,8,8-trimethyl-11-[5-(pyridin-2-yld...)
Affinity DataIC50:  52nMAssay Description:Inhibition of HDAC4 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering

Curated by ChEMBL
LigandPNGBDBM50223504((5S,11S,13aR)-5-isobutyl-8,8-dimethyl-11-[5-(pyrid...)
Affinity DataIC50:  58nMAssay Description:Inhibition of HDAC1 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering

Curated by ChEMBL
LigandPNGBDBM50222727((5S,11S,13aR)-5,8,8-trimethyl-11-[5-(pyridin-2-yld...)
Affinity DataIC50:  94nMAssay Description:Inhibition of HDAC1 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataIC50:  190nMAssay Description:Inhibition of HDAC1 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataIC50:  200nMAssay Description:Inhibition of HDAC4 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering

Curated by ChEMBL
LigandPNGBDBM50223504((5S,11S,13aR)-5-isobutyl-8,8-dimethyl-11-[5-(pyrid...)
Affinity DataIC50:  230nMAssay Description:Inhibition of HDAC6 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering

Curated by ChEMBL
LigandPNGBDBM50223506((5S,11S,13aR)-5-butyl-8,8-dimethyl-11-[5-(pyridin-...)
Affinity DataIC50:  280nMAssay Description:Inhibition of HDAC6 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataIC50:  280nMAssay Description:Inhibition of HDAC6 expressed in 293T cellsMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering

Curated by ChEMBL
LigandPNGBDBM50223505((5S,11S,13aR)-5-((S)-sec-butyl)-8,8-dimethyl-11-[5...)
Affinity DataIC50:  310nMAssay Description:Inhibition of HDAC6 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering

Curated by ChEMBL
LigandPNGBDBM50222732((5S,11S,13aR)-5-benzyl-8,8-dimethyl-11-[5-(pyridin...)
Affinity DataIC50:  404nMAssay Description:Inhibition of HDAC6 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering

Curated by ChEMBL
LigandPNGBDBM50222727((5S,11S,13aR)-5,8,8-trimethyl-11-[5-(pyridin-2-yld...)
Affinity DataIC50:  430nMAssay Description:Inhibition of HDAC6 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering

Curated by ChEMBL
LigandPNGBDBM50223507((1R,14S,20R,23S)-23-[5-(Pyridin-2-yldisulfanyl)-pe...)
Affinity DataIC50:  4.90E+3nMAssay Description:Inhibition of HDAC6 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed