Compile Data Set for Download or QSAR
maximum 50k data
Found 28 Enz. Inhib. hit(s) with all data for entry = 50021355
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50223615(3-bromo-5-cyclohexyl-N-(pyridin-3-ylmethyl)pyrazol...)
Affinity DataIC50:  27nMAssay Description:Inhibition of human GSK3betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50223602(CHEMBL442802 | N-(2-(5-phenyl-7-(pyridin-3-ylmethy...)
Affinity DataIC50:  34nMAssay Description:Inhibition of human GSK3betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50223587(3-bromo-5-(2-chlorophenyl)-N-((pyridin-3-yloxy)met...)
Affinity DataIC50:  35nMAssay Description:Inhibition of human GSK3betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50223567(3-bromo-5-(2-chlorophenyl)-N-(pyridin-3-ylmethyl)p...)
Affinity DataIC50:  54nMAssay Description:Inhibition of human GSK3betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50223590(3-bromo-5-(2-fluorophenyl)-N-((pyridin-3-yloxy)met...)
Affinity DataIC50:  130nMAssay Description:Inhibition of human GSK3betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50223583(3-bromo-5-(piperidin-3-yl)-N-(pyridin-3-ylmethyl)p...)
Affinity DataIC50:  180nMAssay Description:Inhibition of human GSK3betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50223580(3-bromo-5-(2-chlorophenyl)-N-methylpyrazolo[1,5-a]...)
Affinity DataIC50:  247nMAssay Description:Inhibition of human GSK3betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50223591(3-bromo-5-(furan-2-yl)-N-(pyridin-3-ylmethyl)pyraz...)
Affinity DataIC50:  310nMAssay Description:Inhibition of human GSK3betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50223578(3-bromo-5-(piperidin-4-yl)-N-(pyridin-3-ylmethyl)p...)
Affinity DataIC50:  410nMAssay Description:Inhibition of human GSK3betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50223594(3-bromo-5-isopropyl-N-(pyridin-3-ylmethyl)pyrazolo...)
Affinity DataIC50:  420nMAssay Description:Inhibition of human GSK3betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50223593(3-bromo-5-(2-chlorophenyl)-N-(4-(methylsulfonyl)ph...)
Affinity DataIC50:  450nMAssay Description:Inhibition of human GSK3betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50223581(3-bromo-N-(pyridin-3-ylmethyl)-5-(thiophen-2-yl)py...)
Affinity DataIC50:  480nMAssay Description:Inhibition of human GSK3betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50223595(1-(3-bromo-7-(pyridin-3-ylmethylamino)pyrazolo[1,5...)
Affinity DataIC50:  500nMAssay Description:Inhibition of human GSK3betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50223586(3-bromo-5-phenyl-N-(pyridin-3-ylmethyl)pyrazolo[1,...)
Affinity DataIC50:  570nMAssay Description:Inhibition of human GSK3betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50223609(3-bromo-5-phenyl-N-((pyridin-3-yloxy)methyl)pyrazo...)
Affinity DataIC50:  600nMAssay Description:Inhibition of human GSK3betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50223568(CHEMBL250183 | ethyl 3-bromo-7-(pyridin-3-ylmethyl...)
Affinity DataIC50:  790nMAssay Description:Inhibition of human GSK3betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50223608(3-bromo-5-ethyl-N-(pyridin-3-ylmethyl)pyrazolo[1,5...)
Affinity DataIC50:  920nMAssay Description:Inhibition of human GSK3betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50223605(2-(5-phenyl-7-(pyridin-3-ylmethylamino)pyrazolo[1,...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of human GSK3betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50223573(3-bromo-5-cyclopropyl-N-(pyridin-3-ylmethyl)pyrazo...)
Affinity DataIC50:  1.13E+3nMAssay Description:Inhibition of human GSK3betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50223577(3-bromo-5-(methylthio)-N-(pyridin-3-ylmethyl)pyraz...)
Affinity DataIC50:  1.18E+3nMAssay Description:Inhibition of human GSK3betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50223601(3-bromo-5-methoxy-N-(pyridin-3-ylmethyl)pyrazolo[1...)
Affinity DataIC50:  1.41E+3nMAssay Description:Inhibition of human GSK3betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50223592(3-(methylthio)-5-phenyl-N-(pyridin-3-ylmethyl)pyra...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of human GSK3betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50223607(3-ethyl-5-phenyl-N-(pyridin-3-ylmethyl)pyrazolo[1,...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of human GSK3betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50223599(3-bromo-5-methyl-N-(pyridin-3-ylmethyl)pyrazolo[1,...)
Affinity DataIC50:  3.53E+3nMAssay Description:Inhibition of human GSK3betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50223610(3-bromo-N5-methyl-N7-(pyridin-3-ylmethyl)pyrazolo[...)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of human GSK3betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50223576(3-ethynyl-5-phenyl-N-(pyridin-3-ylmethyl)pyrazolo[...)
Affinity DataIC50:  9.82E+3nMAssay Description:Inhibition of human GSK3betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50223570(3-bromo-5-(2-fluorophenyl)-N-phenylpyrazolo[1,5-a]...)
Affinity DataIC50:  1.33E+4nMAssay Description:Inhibition of human GSK3betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50223582(CHEMBL249947 | N-benzyl-3-bromo-5-(2-fluorophenyl)...)
Affinity DataIC50:  1.52E+4nMAssay Description:Inhibition of human GSK3betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed