Compile Data Set for Download or QSAR
maximum 50k data
Found 18 Enz. Inhib. hit(s) with all data for entry = 50021433
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Heriot-Watt University

Curated by ChEMBL
LigandPNGBDBM50224551(CHEMBL400572 | difluoro(4-(2-oxo-1,2-diphenylethyl...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of PTP1B expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Heriot-Watt University

Curated by ChEMBL
LigandPNGBDBM50224541(2-(4-(benzyloxy)-3-(2-(2-(4-chlorophenyl)-4-methyl...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of PTP1B in a cell-free assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Heriot-Watt University

Curated by ChEMBL
LigandPNGBDBM50224541(2-(4-(benzyloxy)-3-(2-(2-(4-chlorophenyl)-4-methyl...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of PTP1B expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Heriot-Watt University

Curated by ChEMBL
LigandPNGBDBM50224537(2-(3-(2-(2-(4-chlorophenyl)-4-methylthiazol-5-yl)e...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of PTP1B expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Heriot-Watt University

Curated by ChEMBL
LigandPNGBDBM50224546(2-(3-(2-(2-(4-chlorophenyl)-4-methylthiazol-5-yl)e...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of PTP1B expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Heriot-Watt University

Curated by ChEMBL
LigandPNGBDBM50224549(2-(4-(4-methoxybenzyloxy)-3-(2-(2-(4-chlorophenyl)...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of PTP1B expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Heriot-Watt University

Curated by ChEMBL
LigandPNGBDBM50224543(2-(4-(4-fluorobenzyloxy)-3-(2-(2-(4-chlorophenyl)-...)
Affinity DataIC50:  2.30E+4nMAssay Description:Inhibition of PTP1B expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Heriot-Watt University

Curated by ChEMBL
LigandPNGBDBM50224536(2-(1-benzyl-5-(2-(2-(4-chlorophenyl)-4-methylthiaz...)
Affinity DataIC50:  2.70E+4nMAssay Description:Inhibition of PTP1B expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Heriot-Watt University

Curated by ChEMBL
LigandPNGBDBM50224548(2-(5-(2-(2-(4-chlorophenyl)-4-methylthiazol-5-yl)e...)
Affinity DataIC50:  3.20E+4nMAssay Description:Inhibition of PTP1B expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Heriot-Watt University

Curated by ChEMBL
LigandPNGBDBM50224542(2-(3-(2-(2-(4-chlorophenyl)-4-methylthiazol-5-yl)e...)
Affinity DataIC50:  3.60E+4nMAssay Description:Inhibition of PTP1B expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Heriot-Watt University

Curated by ChEMBL
LigandPNGBDBM50224545(2-(3-(2-(2-(4-chlorophenyl)-4-methylthiazol-5-yl)e...)
Affinity DataIC50:  3.70E+4nMAssay Description:Inhibition of PTP1B expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Heriot-Watt University

Curated by ChEMBL
LigandPNGBDBM50224550(2-(5-(2-(2-(4-chlorophenyl)-4-methylthiazol-5-yl)e...)
Affinity DataIC50:  5.90E+4nMAssay Description:Inhibition of PTP1B expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Heriot-Watt University

Curated by ChEMBL
LigandPNGBDBM50224547(2-(3-(2-(2-(4-chlorophenyl)-4-methylthiazol-5-yl)e...)
Affinity DataIC50:  1.05E+5nMAssay Description:Inhibition of PTP1B expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Heriot-Watt University

Curated by ChEMBL
LigandPNGBDBM13990(5-{2-fluoro-5-[(1E)-3-[3-hydroxy-2-(methoxycarbony...)
Affinity DataIC50:  1.10E+5nMAssay Description:Inhibition of PTP1B expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Heriot-Watt University

Curated by ChEMBL
LigandPNGBDBM50224540(3,3,3-trifluoro-2-hydroxy-2-(5-(2-(3-hydroxy-2-(me...)
Affinity DataIC50:  1.23E+5nMAssay Description:Inhibition of PTP1B expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Heriot-Watt University

Curated by ChEMBL
LigandPNGBDBM50224538(2-(7-(benzyloxy)-1-(methoxymethyl)-1H-indol-3-yl)-...)
Affinity DataIC50:  1.76E+5nMAssay Description:Inhibition of PTP1B expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Heriot-Watt University

Curated by ChEMBL
LigandPNGBDBM50224539(2-(6-(benzyloxy)-1-(methoxymethyl)-1H-indol-3-yl)-...)
Affinity DataIC50:  3.82E+5nMAssay Description:Inhibition of PTP1B expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Heriot-Watt University

Curated by ChEMBL
LigandPNGBDBM50224544(2-(4-(carboxymethoxy)-3-(2-(2-(4-chlorophenyl)-4-m...)
Affinity DataIC50:  5.00E+5nMAssay Description:Inhibition of PTP1B expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed