Compile Data Set for Download or QSAR
maximum 50k data
Found 47 Enz. Inhib. hit(s) with all data for entry = 50038048
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM35847((15S)-prostaglandin E2 | (5Z,11alpha,13E,15S)-11,1...)
Affinity DataKi:  0.790nMAssay Description:Binding affinity at human prostaglandin EP4 receptorMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM35847((15S)-prostaglandin E2 | (5Z,11alpha,13E,15S)-11,1...)
Affinity DataKi:  4.90nMAssay Description:Binding affinity at human prostaglandin EP2 receptorMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50224577(4-(2-(2-(4-(3-bromophenyl)-3-hydroxybutyl)-5-oxopy...)
Affinity DataKi:  13nMAssay Description:Binding affinity at human prostaglandin EP4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50224575((S)-4-(2-(2-(4-(3-bromophenyl)-3-hydroxybutyl)-5-o...)
Affinity DataKi:  13nMAssay Description:Binding affinity at human prostaglandin EP4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50224572(4-(2-(2-(4-(3-chlorophenyl)-3-hydroxybutyl)-5-oxop...)
Affinity DataKi:  18nMAssay Description:Binding affinity at human prostaglandin EP4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50224570((S)-4-(2-(2-(3-hydroxy-4-(3-iodophenyl)butyl)-5-ox...)
Affinity DataKi:  26nMAssay Description:Binding affinity at human prostaglandin EP4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50224574(4-(2-(2-(3-hydroxy-4-(3-iodophenyl)butyl)-5-oxopyr...)
Affinity DataKi:  27nMAssay Description:Binding affinity at human prostaglandin EP4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50224586(4-(2-(2-(4-(3-fluorophenyl)-3-hydroxybutyl)-5-oxop...)
Affinity DataKi:  36nMAssay Description:Binding affinity at human prostaglandin EP4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50224583(4-(2-(2-(3-methyl-4-(3-phenethylphenyl)butyl)-5-ox...)
Affinity DataKi:  44nMAssay Description:Binding affinity at human prostaglandin EP4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50224584(4-(2-(2-(3-hydroxy-4-(3-(trifluoromethyl)phenyl)bu...)
Affinity DataKi:  57nMAssay Description:Binding affinity at human prostaglandin EP4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50224581(4-(2-(2-(3-hydroxy-4-(3-(trifluoromethoxy)phenyl)b...)
Affinity DataKi:  59nMAssay Description:Binding affinity at human prostaglandin EP4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50224580(4-(2-(2-(3-hydroxy-4-phenylbutyl)-5-oxopyrazolidin...)
Affinity DataKi:  68nMAssay Description:Binding affinity at human prostaglandin EP4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50224578((S)-4-(2-(2-(3-hydroxy-4-phenylbutyl)-5-oxopyrazol...)
Affinity DataKi:  134nMAssay Description:Binding affinity at human prostaglandin EP4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50224571(4-(2-(2-(3-hydroxyoctyl)-5-oxopyrazolidin-1-yl)eth...)
Affinity DataKi:  250nMAssay Description:Binding affinity at human prostaglandin EP4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50224582(4-(2-(2-(4-(3-(2-cyclopropylethyl)phenyl)-3-hydrox...)
Affinity DataKi:  330nMAssay Description:Binding affinity at human prostaglandin EP4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50224583(4-(2-(2-(3-methyl-4-(3-phenethylphenyl)butyl)-5-ox...)
Affinity DataKi:  560nMAssay Description:Binding affinity at human prostaglandin EP2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50224579(4-(2-(2-(4-hydroxy-4-(1-propylcyclobutyl)butyl)-5-...)
Affinity DataKi:  750nMAssay Description:Binding affinity at human prostaglandin EP2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50224576(4-(2-(2-(4-hydroxynonyl)-5-oxopyrazolidin-1-yl)eth...)
Affinity DataKi:  2.00E+3nMAssay Description:Binding affinity at human prostaglandin EP4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50224568(4-(2-(2-(3-hydroxy-5-methylhexyl)-5-oxopyrazolidin...)
Affinity DataKi:  2.00E+3nMAssay Description:Binding affinity at human prostaglandin EP4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50224570((S)-4-(2-(2-(3-hydroxy-4-(3-iodophenyl)butyl)-5-ox...)
Affinity DataKi:  2.03E+3nMAssay Description:Binding affinity at human prostaglandin EP2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50224571(4-(2-(2-(3-hydroxyoctyl)-5-oxopyrazolidin-1-yl)eth...)
Affinity DataKi:  2.20E+3nMAssay Description:Binding affinity at human prostaglandin EP2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50224574(4-(2-(2-(3-hydroxy-4-(3-iodophenyl)butyl)-5-oxopyr...)
Affinity DataKi:  2.36E+3nMAssay Description:Binding affinity at human prostaglandin EP2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50224576(4-(2-(2-(4-hydroxynonyl)-5-oxopyrazolidin-1-yl)eth...)
Affinity DataKi:  2.44E+3nMAssay Description:Binding affinity at human prostaglandin EP2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50224569(4-(2-(2-(3-hydroxy-4-methylheptyl)-5-oxopyrazolidi...)
Affinity DataKi:  2.76E+3nMAssay Description:Binding affinity at human prostaglandin EP2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50224581(4-(2-(2-(3-hydroxy-4-(3-(trifluoromethoxy)phenyl)b...)
Affinity DataKi:  2.83E+3nMAssay Description:Binding affinity at human prostaglandin EP2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50224575((S)-4-(2-(2-(4-(3-bromophenyl)-3-hydroxybutyl)-5-o...)
Affinity DataKi:  3.07E+3nMAssay Description:Binding affinity at human prostaglandin EP2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50224568(4-(2-(2-(3-hydroxy-5-methylhexyl)-5-oxopyrazolidin...)
Affinity DataKi:  4.41E+3nMAssay Description:Binding affinity at human prostaglandin EP2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50224577(4-(2-(2-(4-(3-bromophenyl)-3-hydroxybutyl)-5-oxopy...)
Affinity DataKi:  5.45E+3nMAssay Description:Binding affinity at human prostaglandin EP2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50224572(4-(2-(2-(4-(3-chlorophenyl)-3-hydroxybutyl)-5-oxop...)
Affinity DataKi:  5.69E+3nMAssay Description:Binding affinity at human prostaglandin EP2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50224584(4-(2-(2-(3-hydroxy-4-(3-(trifluoromethyl)phenyl)bu...)
Affinity DataKi:  6.00E+3nMAssay Description:Binding affinity at human prostaglandin EP2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50224569(4-(2-(2-(3-hydroxy-4-methylheptyl)-5-oxopyrazolidi...)
Affinity DataKi:  6.00E+3nMAssay Description:Binding affinity at human prostaglandin EP4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50224580(4-(2-(2-(3-hydroxy-4-phenylbutyl)-5-oxopyrazolidin...)
Affinity DataKi:  6.20E+3nMAssay Description:Binding affinity at human prostaglandin EP2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50224586(4-(2-(2-(4-(3-fluorophenyl)-3-hydroxybutyl)-5-oxop...)
Affinity DataKi:  6.29E+3nMAssay Description:Binding affinity at human prostaglandin EP2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50224582(4-(2-(2-(4-(3-(2-cyclopropylethyl)phenyl)-3-hydrox...)
Affinity DataKi:  8.34E+3nMAssay Description:Binding affinity at human prostaglandin EP2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50224578((S)-4-(2-(2-(3-hydroxy-4-phenylbutyl)-5-oxopyrazol...)
Affinity DataKi:  9.20E+3nMAssay Description:Binding affinity at human prostaglandin EP2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50224579(4-(2-(2-(4-hydroxy-4-(1-propylcyclobutyl)butyl)-5-...)
Affinity DataKi: >5.00E+4nMAssay Description:Binding affinity at human prostaglandin EP4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50224572(4-(2-(2-(4-(3-chlorophenyl)-3-hydroxybutyl)-5-oxop...)
Affinity DataEC50:  0.200nMAssay Description:Agonist activity at human prostaglandin EP4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50224571(4-(2-(2-(3-hydroxyoctyl)-5-oxopyrazolidin-1-yl)eth...)
Affinity DataEC50:  595nMAssay Description:Agonist activity at human prostaglandin EP2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50224568(4-(2-(2-(3-hydroxy-5-methylhexyl)-5-oxopyrazolidin...)
Affinity DataEC50:  1.50E+4nMAssay Description:Agonist activity at human prostaglandin EP2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50224579(4-(2-(2-(4-hydroxy-4-(1-propylcyclobutyl)butyl)-5-...)
Affinity DataEC50:  393nMAssay Description:Agonist activity at human prostaglandin EP2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50224571(4-(2-(2-(3-hydroxyoctyl)-5-oxopyrazolidin-1-yl)eth...)
Affinity DataEC50:  5nMAssay Description:Agonist activity at human prostaglandin EP4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50224577(4-(2-(2-(4-(3-bromophenyl)-3-hydroxybutyl)-5-oxopy...)
Affinity DataEC50:  0.200nMAssay Description:Agonist activity at human prostaglandin EP4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50224569(4-(2-(2-(3-hydroxy-4-methylheptyl)-5-oxopyrazolidi...)
Affinity DataEC50:  5.00E+3nMAssay Description:Agonist activity at human prostaglandin EP2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50224576(4-(2-(2-(4-hydroxynonyl)-5-oxopyrazolidin-1-yl)eth...)
Affinity DataEC50:  1.30E+3nMAssay Description:Agonist activity at human prostaglandin EP2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50224575((S)-4-(2-(2-(4-(3-bromophenyl)-3-hydroxybutyl)-5-o...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human prostaglandin EP2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50224568(4-(2-(2-(3-hydroxy-5-methylhexyl)-5-oxopyrazolidin...)
Affinity DataEC50:  277nMAssay Description:Agonist activity at human prostaglandin EP4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50224575((S)-4-(2-(2-(4-(3-bromophenyl)-3-hydroxybutyl)-5-o...)
Affinity DataEC50:  0.100nMAssay Description:Agonist activity at human prostaglandin EP4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed