Compile Data Set for Download or QSAR
maximum 50k data
Found 75 Enz. Inhib. hit(s) with all data for entry = 2522
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck Serono

LigandPNGBDBM21599(2-{5-chloro-1'-[(3-methyl-5-phenyl-1,2-oxazol-4-yl...)
Affinity DataKi:  3.80nM EC50:  19nMAssay Description:A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Mus musculus (mouse))
Merck Serono

LigandPNGBDBM21610(2-[(3R)-5-chloro-1'-[(5-chloro-2-fluorophenyl)meth...)
Affinity DataKi:  5nMAssay Description:A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck Serono

LigandPNGBDBM21595(2-{5-chloro-1'-[(3-methyl-5-phenyl-1,2-oxazol-4-yl...)
Affinity DataKi:  5.30nM EC50:  23nMAssay Description:A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck Serono

LigandPNGBDBM21610(2-[(3R)-5-chloro-1'-[(5-chloro-2-fluorophenyl)meth...)
Affinity DataKi:  5.30nM EC50:  66nMAssay Description:A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck Serono

LigandPNGBDBM21594(2-{5-chloro-1'-[(5-methyl-3-phenyl-1,2-oxazol-4-yl...)
Affinity DataKi:  7.60nM EC50:  21nMAssay Description:A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck Serono

LigandPNGBDBM21579(2-{5-chloro-1'-[(5-chloro-2-fluorophenyl)methyl]-1...)
Affinity DataKi:  10nM EC50:  48nMAssay Description:A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck Serono

LigandPNGBDBM21596(2-{5-chloro-1'-[(4-methoxy-3,5-dimethylpyridin-2-y...)
Affinity DataKi:  12nMAssay Description:A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck Serono

LigandPNGBDBM21611(2-[(3S)-5-chloro-1'-[(5-chloro-2-fluorophenyl)meth...)
Affinity DataKi:  13nMAssay Description:A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck Serono

LigandPNGBDBM21581(2-{5-chloro-1'-[(3-chloro-5-fluorophenyl)methyl]-1...)
Affinity DataKi:  20nMAssay Description:A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck Serono

LigandPNGBDBM21575(2-{5-chloro-1'-[(2,5-difluorophenyl)methyl]-1,2-di...)
Affinity DataKi:  21nMAssay Description:A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Mus musculus (mouse))
Merck Serono

LigandPNGBDBM21603(2-[(3R)-5-chloro-1'-[(2-fluorophenyl)methyl]-1,2-d...)
Affinity DataKi:  22nMAssay Description:A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck Serono

LigandPNGBDBM21603(2-[(3R)-5-chloro-1'-[(2-fluorophenyl)methyl]-1,2-d...)
Affinity DataKi:  23nMAssay Description:A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck Serono

LigandPNGBDBM21605(2-[(3R)-5-chloro-1'-[(3-chlorophenyl)methyl]-1,2-d...)
Affinity DataKi:  23nM EC50:  107nMAssay Description:A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck Serono

LigandPNGBDBM21585(2-(5-chloro-1'-{[2-(3-chlorophenyl)-1,3-thiazol-4-...)
Affinity DataKi:  24nM EC50:  48nMAssay Description:A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck Serono

LigandPNGBDBM21574(2-{5-chloro-1'-[(2,3-difluorophenyl)methyl]-1,2-di...)
Affinity DataKi:  25nM EC50:  296nMAssay Description:A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck Serono

LigandPNGBDBM21598(2-{5-chloro-1'-[(5-chloro-2-fluorophenyl)methyl]-1...)
Affinity DataKi:  32nMAssay Description:A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Mus musculus (mouse))
Merck Serono

LigandPNGBDBM21605(2-[(3R)-5-chloro-1'-[(3-chlorophenyl)methyl]-1,2-d...)
Affinity DataKi:  33nMAssay Description:A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck Serono

LigandPNGBDBM21580(2-{5-chloro-1'-[(3,5-dichlorophenyl)methyl]-1,2-di...)
Affinity DataKi:  36nM EC50:  82nMAssay Description:A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck Serono

LigandPNGBDBM21566(2-{5-chloro-1'-[(2-fluorophenyl)methyl]-1,2-dihydr...)
Affinity DataKi:  37nM ΔG°:  -42.0kJ/mole EC50:  212nMpH: 7.4 T: 2°CAssay Description:A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck Serono

LigandPNGBDBM21576(2-{5-chloro-1'-[(3,5-difluorophenyl)methyl]-1,2-di...)
Affinity DataKi:  37nMAssay Description:A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck Serono

LigandPNGBDBM21584(2-{5-chloro-1'-[(2-methyl-1,3-thiazol-4-yl)methyl]...)
Affinity DataKi:  38nM EC50:  236nMAssay Description:A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck Serono

LigandPNGBDBM21578(2-{5-chloro-1'-[(2-chloro-5-fluorophenyl)methyl]-1...)
Affinity DataKi:  43nMAssay Description:A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck Serono

LigandPNGBDBM21593(2-{5-chloro-1'-[(3,5-dimethyl-1,2-oxazol-4-yl)meth...)
Affinity DataKi:  51nM EC50:  220nMAssay Description:A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck Serono

LigandPNGBDBM21586(2-(5-chloro-1'-{[2-(4-chlorophenyl)-1,3-thiazol-4-...)
Affinity DataKi:  55nMAssay Description:A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck Serono

LigandPNGBDBM21568(2-{5-chloro-1'-[(3-chlorophenyl)methyl]-1,2-dihydr...)
Affinity DataKi:  68nM ΔG°:  -40.5kJ/mole EC50:  122nMpH: 7.4 T: 2°CAssay Description:A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck Serono

LigandPNGBDBM21607(2-[(3R)-5-chloro-1'-[(3-methoxyphenyl)methyl]-1,2-...)
Affinity DataKi:  72nMAssay Description:A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck Serono

LigandPNGBDBM21601(2-[(3R)-1'-benzyl-5-chloro-1,2-dihydrospiro[indole...)
Affinity DataKi:  81nMAssay Description:A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Mus musculus (mouse))
Merck Serono

LigandPNGBDBM21611(2-[(3S)-5-chloro-1'-[(5-chloro-2-fluorophenyl)meth...)
Affinity DataKi:  88nMAssay Description:A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck Serono

LigandPNGBDBM21577(2-{5-chloro-1'-[(3,4-difluorophenyl)methyl]-1,2-di...)
Affinity DataKi:  89nMAssay Description:A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck Serono

LigandPNGBDBM21567(2-{5-chloro-1'-[(4-fluorophenyl)methyl]-1,2-dihydr...)
Affinity DataKi:  96nM ΔG°:  -39.7kJ/mole EC50:  182nMpH: 7.4 T: 2°CAssay Description:A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck Serono

LigandPNGBDBM21569(2-{5-chloro-1'-[(4-chlorophenyl)methyl]-1,2-dihydr...)
Affinity DataKi:  115nM ΔG°:  -39.2kJ/molepH: 7.4 T: 2°CAssay Description:A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck Serono

LigandPNGBDBM21572(2-{5-chloro-1'-[(4-phenoxyphenyl)methyl]-1,2-dihyd...)
Affinity DataKi:  143nMAssay Description:A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Mus musculus (mouse))
Merck Serono

LigandPNGBDBM21543(2-{1'-benzyl-5-chloro-1,2-dihydrospiro[indole-3,3'...)
Affinity DataKi:  150nM ΔG°:  -38.6kJ/molepH: 7.4 T: 2°CAssay Description:A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck Serono

LigandPNGBDBM21582(2-{5-chloro-1'-[(3-fluoro-4-methoxyphenyl)methyl]-...)
Affinity DataKi:  154nMAssay Description:A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck Serono

LigandPNGBDBM21571(2-{5-chloro-1'-[(3-methoxyphenyl)methyl]-1,2-dihyd...)
Affinity DataKi:  169nMAssay Description:A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck Serono

LigandPNGBDBM21543(2-{1'-benzyl-5-chloro-1,2-dihydrospiro[indole-3,3'...)
Affinity DataKi:  196nM ΔG°:  -37.9kJ/mole EC50:  418nMpH: 7.4 T: 2°CAssay Description:A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck Serono

LigandPNGBDBM21587(2-(5-chloro-1'-{[5-(4-methoxyphenyl)-1,2,4-oxadiaz...)
Affinity DataKi:  212nMAssay Description:A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck Serono

LigandPNGBDBM21570(2-{5-chloro-1'-[(2-methoxyphenyl)methyl]-1,2-dihyd...)
Affinity DataKi:  233nMAssay Description:A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck Serono

LigandPNGBDBM21563(2-[5-chloro-1'-(2-phenylethyl)-1,2-dihydrospiro[in...)
Affinity DataKi:  267nM ΔG°:  -37.1kJ/molepH: 7.4 T: 2°CAssay Description:A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck Serono

LigandPNGBDBM21609(2-[(3S)-5-chloro-1'-[(5-chloro-2-fluorophenyl)meth...)
Affinity DataKi:  302nMAssay Description:A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck Serono

LigandPNGBDBM21591(2-[5-chloro-1'-(furan-3-ylmethyl)-1,2-dihydrospiro...)
Affinity DataKi:  318nMAssay Description:A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck Serono

LigandPNGBDBM21565(2-[5-chloro-1'-(1-phenylethyl)-1,2-dihydrospiro[in...)
Affinity DataKi:  356nM ΔG°:  -36.4kJ/molepH: 7.4 T: 2°CAssay Description:A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck Serono

LigandPNGBDBM21589(2-[5-chloro-1'-(1,3-oxazol-2-ylmethyl)-1,2-dihydro...)
Affinity DataKi:  438nMAssay Description:A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Mus musculus (mouse))
Merck Serono

LigandPNGBDBM21597(2-{1'-benzyl-5-chloro-1,2-dihydrospiro[indole-3,3'...)
Affinity DataKi:  480nMAssay Description:A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck Serono

LigandPNGBDBM21590(2-{5-chloro-1'-[(5-cyclopropyl-1,3,4-thiadiazol-2-...)
Affinity DataKi:  497nMAssay Description:A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck Serono

LigandPNGBDBM21592(2-[5-chloro-1'-(1H-indol-3-ylmethyl)-1,2-dihydrosp...)
Affinity DataKi:  596nMAssay Description:A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck Serono

LigandPNGBDBM21612(2-[(3R)-5-chloro-1'-[(5-chloro-2-fluorophenyl)meth...)
Affinity DataKi:  683nMAssay Description:A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck Serono

LigandPNGBDBM21597(2-{1'-benzyl-5-chloro-1,2-dihydrospiro[indole-3,3'...)
Affinity DataKi:  702nMAssay Description:A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck Serono

LigandPNGBDBM21545(2-{1'-benzyl-5-fluoro-1,2-dihydrospiro[indole-3,3'...)
Affinity DataKi:  712nM ΔG°:  -34.7kJ/molepH: 7.4 T: 2°CAssay Description:A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck Serono

LigandPNGBDBM21564(2-{5-chloro-1'-[(2E)-3-phenylprop-2-en-1-yl]-1,2-d...)
Affinity DataKi:  747nM ΔG°:  -34.6kJ/molepH: 7.4 T: 2°CAssay Description:A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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