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Found 11 Enz. Inhib. hit(s) with all data for entry = 50026185
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut FüR Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  2.20nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membrane by liquid scintillation analyzerMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut FüR Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50267352((-)-[(2R)-(1,4-Dibenzyl)-1,4-diazepan-2-yl]methano...)
Affinity DataKi:  7.40nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membrane by liquid scintillation analyzerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut FüR Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50267386((R)-(1,4-dibenzylpiperazin-2-yl)methanol | CHEMBL4...)
Affinity DataKi:  38nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membrane by liquid scintillation analyzerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut FüR Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM81982(CAS_97-39-2 | DITOLYLGUANIDINE | DTG | Di-o-tolylg...)
Affinity DataKi:  164nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membrane by liquid scintillation analyzerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut FüR Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50002238((R)1-(4-Fluoro-phenyl)-4-[4-(5-fluoro-pyrimidin-2-...)
Affinity DataKi:  265nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membrane by liquid scintillation analyzerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut FüR Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50267353((-)-[(2R)-1-Benzyl-4-(2,2-dimethoxyethyl)-1,4-diaz...)
Affinity DataKi:  320nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membrane by liquid scintillation analyzerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut FüR Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50267387((R)-(1-benzyl-4-(2,2-dimethoxyethyl)piperazin-2-yl...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membrane by liquid scintillation analyzerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Institut FüR Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50267353((-)-[(2R)-1-Benzyl-4-(2,2-dimethoxyethyl)-1,4-diaz...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]U-69593 from kappa opioid receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Institut FüR Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50267352((-)-[(2R)-(1,4-Dibenzyl)-1,4-diazepan-2-yl]methano...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of radioligand from mu opioid receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Institut FüR Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50267352((-)-[(2R)-(1,4-Dibenzyl)-1,4-diazepan-2-yl]methano...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]U-69593 from kappa opioid receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Institut FüR Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50267353((-)-[(2R)-1-Benzyl-4-(2,2-dimethoxyethyl)-1,4-diaz...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of radioligand from mu opioid receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed