Compile Data Set for Download or QSAR
maximum 50k data
Found 47 Enz. Inhib. hit(s) with all data for entry = 50026320
TargetIntegrin alpha-4(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50243822((S)-2-(2-Bromo-3-oxo-spiro[3.5]non-1-en-1-ylamino)...)
Affinity DataIC50:  2nMAssay Description:Inhibition of integrin alpha4beta1 receptor in human whole blood by flow cytometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50243737((S)-2-(2-Isopropylsulfanyl-3-oxo-spiro[3.5]non-1-e...)
Affinity DataIC50:  2nMAssay Description:Inhibition of integrin alpha4beta1 receptor in human whole blood by flow cytometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50243738((S)-2-(2-Methylsulfanyl-3-oxo-spiro[3.5]non-1-en-1...)
Affinity DataIC50:  2nMAssay Description:Inhibition of integrin alpha4beta1 receptor in human whole blood by flow cytometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50243759((S)-2-(2-Bromo-3-oxo-spiro[3.5]non-1-en-1-ylamino)...)
Affinity DataIC50:  3nMAssay Description:Inhibition of integrin alpha4beta1 receptor in human whole blood by flow cytometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50243823((S)-2-(2-Bromo-3-oxo-spiro[3.5]non-1-en-1-ylamino)...)
Affinity DataIC50:  3nMAssay Description:Inhibition of integrin alpha4beta1 receptor in human whole blood by flow cytometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50243736((S)-2-(2-Bromo-3-oxo-spiro[3.5]non-1-en-1-ylamino)...)
Affinity DataIC50:  3nMAssay Description:Inhibition of integrin alpha4beta1 receptor in human whole blood by flow cytometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50243758((S)-2-(2-Bromo-3-oxo-spiro[3.5]non-1-en-1-ylamino)...)
Affinity DataIC50:  3nMAssay Description:Inhibition of integrin alpha4beta1 receptor in human whole blood by flow cytometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50243824((S)-2-(2-Bromo-3-oxo-spiro[3.5]non-1-en-1-ylamino)...)
Affinity DataIC50:  6nMAssay Description:Inhibition of integrin alpha4beta1 receptor in human whole blood by flow cytometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50243735((S)-2-(2-Chloro-3-oxo-spiro[3.5]non-1-en-1-ylamino...)
Affinity DataIC50:  7nMAssay Description:Inhibition of integrin alpha4beta1 receptor in human whole blood by flow cytometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50243821((S)-2-(2-Bromo-3-oxo-spiro[3.5]non-1-en-1-ylamino)...)
Affinity DataIC50:  8nMAssay Description:Inhibition of integrin alpha4beta1 receptor in human whole blood by flow cytometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50243820((S)-2-(2-Bromo-3-oxo-spiro[3.5]non-1-en-1-ylamino)...)
Affinity DataIC50:  8nMAssay Description:Inhibition of integrin alpha4beta1 receptor in human whole blood by flow cytometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50243818((S)-2-(2-Bromo-3-oxo-spiro[3.5]non-1-en-1-ylamino)...)
Affinity DataIC50:  9nMAssay Description:Inhibition of integrin alpha4beta1 receptor in human whole blood by flow cytometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50243819((S)-2-(2-Bromo-3-oxo-spiro[3.5]non-1-en-1-ylamino)...)
Affinity DataIC50:  9nMAssay Description:Inhibition of integrin alpha4beta1 receptor in human whole blood by flow cytometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50243757((S)-2-(2-Bromo-3-oxo-spiro[3.5]non-1-en-1-ylamino)...)
Affinity DataIC50:  10nMAssay Description:Inhibition of integrin alpha4beta1 receptor in human whole blood by flow cytometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50243756((S)-2-(2-Bromo-3-oxo-spiro[3.5]non-1-en-1-ylamino)...)
Affinity DataIC50:  10nMAssay Description:Inhibition of integrin alpha4beta1 receptor in human whole blood by flow cytometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50244342((2S)-2-(2-bromo-4,4-dimethyl-3-oxocyclobut-1-enyla...)
Affinity DataIC50:  10nMAssay Description:Inhibition of integrin alpha4beta1 receptor in human whole blood by flow cytometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50243815((S)-2-(2-Bromo-3-oxo-spiro[3.5]non-1-en-1-ylamino)...)
Affinity DataIC50:  11nMAssay Description:Inhibition of integrin alpha4beta1 receptor in human whole blood by flow cytometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50243755((S)-2-(2-Bromo-3-oxo-spiro[3.5]non-1-en-1-ylamino)...)
Affinity DataIC50:  11nMAssay Description:Inhibition of integrin alpha4beta1 receptor in human whole blood by flow cytometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50243817((S)-2-(2-Bromo-3-oxo-spiro[3.5]non-1-en-1-ylamino)...)
Affinity DataIC50:  13nMAssay Description:Inhibition of integrin alpha4beta1 receptor in human whole blood by flow cytometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50243816((S)-2-(2-Bromo-3-oxo-spiro[3.5]non-1-en-1-ylamino)...)
Affinity DataIC50:  14nMAssay Description:Inhibition of integrin alpha4beta1 receptor in human whole blood by flow cytometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50243814((S)-2-(2-Bromo-3-oxo-spiro[3.5]non-1-en-1-ylamino)...)
Affinity DataIC50:  18nMAssay Description:Inhibition of integrin alpha4beta1 receptor in human whole blood by flow cytometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50244341((2S)-2-(2-chloro-4,4-dimethyl-3-oxocyclobut-1-enyl...)
Affinity DataIC50:  19nMAssay Description:Inhibition of integrin alpha4beta1 receptor in human whole blood by flow cytometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50243753((S)-2-(2-Bromo-3-oxo-spiro[3.5]non-1-en-1-ylamino)...)
Affinity DataIC50:  22nMAssay Description:Inhibition of integrin alpha4beta1 receptor in human whole blood by flow cytometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50243752((S)-2-(2-Bromo-3-oxo-spiro[3.5]non-1-en-1-ylamino)...)
Affinity DataIC50:  22nMAssay Description:Inhibition of integrin alpha4beta1 receptor in human whole blood by flow cytometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50244384((S)-2-(3-Oxo-spiro[3.5]non-1-en-1-ylamino)-3-[4-(2...)
Affinity DataIC50:  24nMAssay Description:Inhibition of integrin alpha4beta1 receptor in human whole blood by flow cytometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50243750((S)-2-(2-Bromo-3-oxo-spiro[3.5]non-1-en-1-ylamino)...)
Affinity DataIC50:  46nMAssay Description:Inhibition of integrin alpha4beta1 receptor in human whole blood by flow cytometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50243751((S)-2-(2-Bromo-3-oxo-spiro[3.5]non-1-en-1-ylamino)...)
Affinity DataIC50:  71nMAssay Description:Inhibition of integrin alpha4beta1 receptor in human whole blood by flow cytometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50243749((S)-2-(2-Bromo-3-oxo-spiro[3.5]non-1-en-1-ylamino)...)
Affinity DataIC50:  83nMAssay Description:Inhibition of integrin alpha4beta1 receptor in human whole blood by flow cytometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50243748((S)-2-(2-Bromo-3-oxo-spiro[3.5]non-1-en-1-ylamino)...)
Affinity DataIC50:  95nMAssay Description:Inhibition of integrin alpha4beta1 receptor in human whole blood by flow cytometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50244308((2S)-2-(4,4-dimethyl-3-oxocyclobut-1-enylamino)-3-...)
Affinity DataIC50:  126nMAssay Description:Inhibition of integrin alpha4beta1 receptor in human whole blood by flow cytometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50244382((S)-2-(2-Bromo-3-oxo-spiro[3.5]non-1-en-1-ylamino)...)
Affinity DataIC50:  236nMAssay Description:Inhibition of integrin alpha4beta1 receptor in human whole blood by flow cytometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50244344((S)-2-(2-Chloro-3-oxo-spiro[3.5]non-1-en-1-ylamino...)
Affinity DataIC50:  504nMAssay Description:Inhibition of integrin alpha4beta1 receptor in human whole blood by flow cytometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50243806((S)-2-(2-Bromo-3-oxo-spiro[3.5]non-1-en-1-ylamino)...)
Affinity DataIC50:  570nMAssay Description:Inhibition of integrin alpha4beta1 receptor in human whole blood by flow cytometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50244343((S)-2-(3-Oxo-spiro[3.5]non-1-en-1-ylamino)-3-[4-(2...)
Affinity DataIC50:  1.62E+3nMAssay Description:Inhibition of integrin alpha4beta1 receptor in human whole blood by flow cytometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50244383((S)-2-(2-Bromo-3-oxo-spiro[3.5]non-1-en-1-ylamino)...)
Affinity DataIC50:  2.68E+3nMAssay Description:Inhibition of integrin alpha4beta1 receptor in human whole blood by flow cytometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50243822((S)-2-(2-Bromo-3-oxo-spiro[3.5]non-1-en-1-ylamino)...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50243822((S)-2-(2-Bromo-3-oxo-spiro[3.5]non-1-en-1-ylamino)...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50243736((S)-2-(2-Bromo-3-oxo-spiro[3.5]non-1-en-1-ylamino)...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50243818((S)-2-(2-Bromo-3-oxo-spiro[3.5]non-1-en-1-ylamino)...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50243736((S)-2-(2-Bromo-3-oxo-spiro[3.5]non-1-en-1-ylamino)...)
Affinity DataIC50:  6.20E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50243818((S)-2-(2-Bromo-3-oxo-spiro[3.5]non-1-en-1-ylamino)...)
Affinity DataIC50:  7.90E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50243818((S)-2-(2-Bromo-3-oxo-spiro[3.5]non-1-en-1-ylamino)...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50243822((S)-2-(2-Bromo-3-oxo-spiro[3.5]non-1-en-1-ylamino)...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50243822((S)-2-(2-Bromo-3-oxo-spiro[3.5]non-1-en-1-ylamino)...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50243736((S)-2-(2-Bromo-3-oxo-spiro[3.5]non-1-en-1-ylamino)...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50243736((S)-2-(2-Bromo-3-oxo-spiro[3.5]non-1-en-1-ylamino)...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50243818((S)-2-(2-Bromo-3-oxo-spiro[3.5]non-1-en-1-ylamino)...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed