Compile Data Set for Download or QSAR
maximum 50k data
Found 17 Enz. Inhib. hit(s) with all data for entry = 2916
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Gsk

LigandPNGBDBM25391(CHEMBL200622 | SB-590885 | SB590885 | [2-(4-{4-[(1...)
Affinity DataKd:  0.300nMpH: 7.5 T: 2°CAssay Description:The kinase enzyme, fluorescent ligand and a variable concentration of test compound are incubated together to reach thermodynamic equilibrium under c...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Gsk

LigandPNGBDBM26056((1E)-5-[5-(morpholin-4-ylmethyl)-2-(pyridin-4-yl)f...)
Affinity DataKd:  7.20nMpH: 7.5 T: 2°CAssay Description:The kinase enzyme, fluorescent ligand and a variable concentration of test compound are incubated together to reach thermodynamic equilibrium under c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Gsk

LigandPNGBDBM26042(imidazole-based compound, 3 | {1-[(4-{4-[(1E)-1-(h...)
Affinity DataKd:  0.5nMpH: 7.5 T: 2°CAssay Description:The kinase enzyme, fluorescent ligand and a variable concentration of test compound are incubated together to reach thermodynamic equilibrium under c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Gsk

LigandPNGBDBM26043(2-{4-[(1E)-1-(hydroxyimino)-2,3-dihydro-1H-inden-5...)
Affinity DataKd:  4.90nMpH: 7.5 T: 2°CAssay Description:The kinase enzyme, fluorescent ligand and a variable concentration of test compound are incubated together to reach thermodynamic equilibrium under c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Gsk

LigandPNGBDBM26044((1E)-5-[2-(piperidin-4-yl)-5-(pyridin-4-yl)-1H-imi...)
Affinity DataKd:  1.70nMpH: 7.5 T: 2°CAssay Description:The kinase enzyme, fluorescent ligand and a variable concentration of test compound are incubated together to reach thermodynamic equilibrium under c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Gsk

LigandPNGBDBM26045((1E)-5-{2-[1-(2-methoxyethyl)piperidin-4-yl]-5-(py...)
Affinity DataKd:  6.30nMpH: 7.5 T: 2°CAssay Description:The kinase enzyme, fluorescent ligand and a variable concentration of test compound are incubated together to reach thermodynamic equilibrium under c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Gsk

LigandPNGBDBM26046((1E)-5-[2-(morpholin-4-ylmethyl)-5-(pyridin-4-yl)-...)
Affinity DataKd:  15.8nMpH: 7.5 T: 2°CAssay Description:The kinase enzyme, fluorescent ligand and a variable concentration of test compound are incubated together to reach thermodynamic equilibrium under c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Gsk

LigandPNGBDBM26047(4-[(1E)-1-(hydroxyimino)-2,3-dihydro-1H-inden-5-yl...)
Affinity DataKd:  1.40nMpH: 7.5 T: 2°CAssay Description:The kinase enzyme, fluorescent ligand and a variable concentration of test compound are incubated together to reach thermodynamic equilibrium under c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Gsk

LigandPNGBDBM26048(N-{3-[(dimethylamino)methyl]phenyl}-4-[(1E)-1-(hyd...)
Affinity DataKd:  1.30nMpH: 7.5 T: 2°CAssay Description:The kinase enzyme, fluorescent ligand and a variable concentration of test compound are incubated together to reach thermodynamic equilibrium under c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Gsk

LigandPNGBDBM26049([2-(4-{4-[(1E)-1-(hydroxyimino)-2,3-dihydro-1H-ind...)
Affinity DataKd:  0.5nMpH: 7.5 T: 2°CAssay Description:The kinase enzyme, fluorescent ligand and a variable concentration of test compound are incubated together to reach thermodynamic equilibrium under c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Gsk

LigandPNGBDBM26050([2-(4-{4-[(1E)-1-(hydroxyimino)-2,3-dihydro-1H-ind...)
Affinity DataKd:  0.700nMpH: 7.5 T: 2°CAssay Description:The kinase enzyme, fluorescent ligand and a variable concentration of test compound are incubated together to reach thermodynamic equilibrium under c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Gsk

LigandPNGBDBM26051([2-(4-{5-[(1E)-1-(hydroxyimino)-2,3-dihydro-1H-ind...)
Affinity DataKd:  0.900nMpH: 7.5 T: 2°CAssay Description:The kinase enzyme, fluorescent ligand and a variable concentration of test compound are incubated together to reach thermodynamic equilibrium under c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Gsk

LigandPNGBDBM26052([2-(4-{5-[(1E)-1-(hydroxyimino)-2,3-dihydro-1H-ind...)
Affinity DataKd:  2.40nMpH: 7.5 T: 2°CAssay Description:The kinase enzyme, fluorescent ligand and a variable concentration of test compound are incubated together to reach thermodynamic equilibrium under c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Gsk

LigandPNGBDBM26053((1E)-5-[5-(piperidin-4-yl)-2-(pyridin-4-yl)furan-3...)
Affinity DataKd:  2.40nMpH: 7.5 T: 2°CAssay Description:The kinase enzyme, fluorescent ligand and a variable concentration of test compound are incubated together to reach thermodynamic equilibrium under c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Gsk

LigandPNGBDBM26054((1E)-5-{5-[1-(2-methoxyethyl)piperidin-4-yl]-2-(py...)
Affinity DataKd:  2.70nMpH: 7.5 T: 2°CAssay Description:The kinase enzyme, fluorescent ligand and a variable concentration of test compound are incubated together to reach thermodynamic equilibrium under c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Gsk

LigandPNGBDBM26055(N-[2-(dimethylamino)ethyl]-4-[(1E)-1-(hydroxyimino...)
Affinity DataKd:  0.5nMpH: 7.5 T: 2°CAssay Description:The kinase enzyme, fluorescent ligand and a variable concentration of test compound are incubated together to reach thermodynamic equilibrium under c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Gsk

LigandPNGBDBM26041(2-chloro-5-(2-phenyl-5-(pyridin-4-yl)-1H-imidazol-...)
Affinity DataKd:  2.40nMpH: 7.5 T: 2°CAssay Description:The kinase enzyme, fluorescent ligand and a variable concentration of test compound are incubated together to reach thermodynamic equilibrium under c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed