TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Affinity DataKi: 0.0100nMAssay Description:Displacement of [I125]CGRP from human CGRP receptor in SK-N-MC cellsMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Affinity DataKi: 0.0128nMAssay Description:Displacement of [I125]CGRP from human CGRP receptor in SK-N-MC cellsMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Affinity DataKi: 0.260nMAssay Description:Displacement of [I125]CGRP from human CGRP receptor in SK-N-MC cellsMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Affinity DataKi: 0.550nMAssay Description:Displacement of [I125]CGRP from human CGRP receptor in SK-N-MC cellsMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor(Rattus norvegicus)
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [I125]CGRP from rat CGRP receptorMore data for this Ligand-Target Pair
TargetIsoform 1 of Calcitonin receptor (1)(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [125I]calcitonin from calcitonin receptor in human T47D cellsMore data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Affinity DataIC50: 84nMAssay Description:Inhibition of recombinant CYP3A4 (unknown origin) expressed in insect microsomes after 20 mins in presence of BFC substrateMore data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Affinity DataIC50: 870nMAssay Description:Inhibition of recombinant CYP3A4 (unknown origin) expressed in insect microsomes after 45 mins in presence of BZR substrateMore data for this Ligand-Target Pair
TargetCytochrome P450 2D6(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of CYP2D6-mediated metabolism of dextromethorphan in human liver microsomesMore data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of recombinant CYP3A4 (unknown origin) expressed in insect microsomes after 20 mins in presence of BFC substrateMore data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of recombinant CYP3A4 (unknown origin) expressed in insect microsomes after 20 mins in presence of BFC substrateMore data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of recombinant CYP3A4 (unknown origin) expressed in insect microsomes after 20 mins in presence of BFC substrateMore data for this Ligand-Target Pair
TargetCytochrome P450 2D6(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human recombinant CYP2D6 expressed in insect microsomes by AMMC assayMore data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of recombinant CYP3A4 (unknown origin) expressed in insect microsomes after 45 mins in presence of BZR substrateMore data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibition of recombinant CYP3A4 (unknown origin) expressed in insect microsomes after 45 mins in presence of BZR substrateMore data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of recombinant CYP3A4 expressed in insect microsomes after 20 mins in presence of BFC substrateMore data for this Ligand-Target Pair
TargetCytochrome P450 2C19(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of human recombinant CYP2C19 expressed in insect microsomesMore data for this Ligand-Target Pair
TargetCytochrome P450 2C9(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of human recombinant CYP2C9 expressed in insect microsomesMore data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of recombinant CYP3A4 (unknown origin) expressed in insect microsomes after 45 mins in presence of BZR substrateMore data for this Ligand-Target Pair
TargetCytochrome P450 1A2(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of human recombinant CYP1A2 expressed in insect microsomesMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Affinity DataEC50: 0.0345nMAssay Description:Antagonist activity at human CGRP receptor in SK-N-MC cells assessed as inhibition of CGRP-stimulated cAMP productionMore data for this Ligand-Target Pair