Compile Data Set for Download or QSAR
maximum 50k data
Found 41 Enz. Inhib. hit(s) with all data for entry = 50026781
TargetHistone deacetylase 2(Homo sapiens (Human))
Institute Of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50268097(6-{[2-(9H-Fluoren-9-yliden)acetyl]amino}-N-hydroxy...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of human recombinant HDAC2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Institute Of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50268097(6-{[2-(9H-Fluoren-9-yliden)acetyl]amino}-N-hydroxy...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of human recombinant HDAC4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Institute Of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50268097(6-{[2-(9H-Fluoren-9-yliden)acetyl]amino}-N-hydroxy...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Institute Of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50268097(6-{[2-(9H-Fluoren-9-yliden)acetyl]amino}-N-hydroxy...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human recombinant HDAC6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 9(Homo sapiens (Human))
Institute Of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50268097(6-{[2-(9H-Fluoren-9-yliden)acetyl]amino}-N-hydroxy...)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of human recombinant HDAC9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Institute Of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50268121((E)-3-(4-Chloro-2-fluorophenyl)-N-[6-(hydroxyamino...)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of human recombinant HDAC6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Institute Of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50268063((E)-N-[6-(Hydroxyamino)-6-oxohexyl]-3-(7-quinoliny...)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of human recombinant HDAC2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Institute Of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50268097(6-{[2-(9H-Fluoren-9-yliden)acetyl]amino}-N-hydroxy...)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of human recombinant HDAC3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 9(Homo sapiens (Human))
Institute Of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50268063((E)-N-[6-(Hydroxyamino)-6-oxohexyl]-3-(7-quinoliny...)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of human recombinant HDAC9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Institute Of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50268063((E)-N-[6-(Hydroxyamino)-6-oxohexyl]-3-(7-quinoliny...)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Institute Of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50268121((E)-3-(4-Chloro-2-fluorophenyl)-N-[6-(hydroxyamino...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human recombinant HDAC2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
Institute Of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50268063((E)-N-[6-(Hydroxyamino)-6-oxohexyl]-3-(7-quinoliny...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human recombinant HDAC7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Institute Of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50268042((2E,4E)-N-[6-(Hydroxyamino)-6-oxohexyl]-3-methyl-5...)
Affinity DataIC50:  3.10nMAssay Description:Inhibition of human recombinant HDAC2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Institute Of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50268121((E)-3-(4-Chloro-2-fluorophenyl)-N-[6-(hydroxyamino...)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Institute Of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50268063((E)-N-[6-(Hydroxyamino)-6-oxohexyl]-3-(7-quinoliny...)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of human recombinant HDAC6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Institute Of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50268042((2E,4E)-N-[6-(Hydroxyamino)-6-oxohexyl]-3-methyl-5...)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of human recombinant HDAC6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Institute Of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50268042((2E,4E)-N-[6-(Hydroxyamino)-6-oxohexyl]-3-methyl-5...)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Institute Of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50268042((2E,4E)-N-[6-(Hydroxyamino)-6-oxohexyl]-3-methyl-5...)
Affinity DataIC50:  3.70nMAssay Description:Inhibition of human recombinant HDAC4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 9(Homo sapiens (Human))
Institute Of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50268121((E)-3-(4-Chloro-2-fluorophenyl)-N-[6-(hydroxyamino...)
Affinity DataIC50:  3.90nMAssay Description:Inhibition of human recombinant HDAC9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 9(Homo sapiens (Human))
Institute Of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50268042((2E,4E)-N-[6-(Hydroxyamino)-6-oxohexyl]-3-methyl-5...)
Affinity DataIC50:  4.20nMAssay Description:Inhibition of human recombinant HDAC9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Institute Of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50268121((E)-3-(4-Chloro-2-fluorophenyl)-N-[6-(hydroxyamino...)
Affinity DataIC50:  4.30nMAssay Description:Inhibition of human recombinant HDAC4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
Institute Of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50268042((2E,4E)-N-[6-(Hydroxyamino)-6-oxohexyl]-3-methyl-5...)
Affinity DataIC50:  4.40nMAssay Description:Inhibition of human recombinant HDAC7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Institute Of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50268121((E)-3-(4-Chloro-2-fluorophenyl)-N-[6-(hydroxyamino...)
Affinity DataIC50:  4.90nMAssay Description:Inhibition of human recombinant HDAC3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Institute Of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50268063((E)-N-[6-(Hydroxyamino)-6-oxohexyl]-3-(7-quinoliny...)
Affinity DataIC50:  5.30nMAssay Description:Inhibition of human recombinant HDAC4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Institute Of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50268042((2E,4E)-N-[6-(Hydroxyamino)-6-oxohexyl]-3-methyl-5...)
Affinity DataIC50:  5.30nMAssay Description:Inhibition of human recombinant HDAC3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
Institute Of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50268121((E)-3-(4-Chloro-2-fluorophenyl)-N-[6-(hydroxyamino...)
Affinity DataIC50:  6.30nMAssay Description:Inhibition of human recombinant HDAC7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Institute Of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50268063((E)-N-[6-(Hydroxyamino)-6-oxohexyl]-3-(7-quinoliny...)
Affinity DataIC50:  6.70nMAssay Description:Inhibition of human recombinant HDAC3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
Institute Of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50268063((E)-N-[6-(Hydroxyamino)-6-oxohexyl]-3-(7-quinoliny...)
Affinity DataIC50:  7.60nMAssay Description:Inhibition of human recombinant HDAC5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Institute Of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  67nMAssay Description:Inhibition of human recombinant HDAC3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetHistone deacetylase 1(Homo sapiens (Human))
Institute Of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  68nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
TargetHistone deacetylase 4(Homo sapiens (Human))
Institute Of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  101nMAssay Description:Inhibition of human recombinant HDAC4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
Institute Of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  102nMAssay Description:Inhibition of human recombinant HDAC7More data for this Ligand-Target Pair
TargetHistone deacetylase 5(Homo sapiens (Human))
Institute Of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  107nMAssay Description:Inhibition of human recombinant HDAC5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 9(Homo sapiens (Human))
Institute Of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  107nMAssay Description:Inhibition of human recombinant HDAC9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Institute Of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  111nMAssay Description:Inhibition of human recombinant HDAC6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetHistone deacetylase 2(Homo sapiens (Human))
Institute Of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  164nMAssay Description:Inhibition of human recombinant HDAC2More data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Institute Of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50268097(6-{[2-(9H-Fluoren-9-yliden)acetyl]amino}-N-hydroxy...)
Affinity DataIC50:  779nMAssay Description:Inhibition of human recombinant HDAC8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Institute Of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  1.38E+3nMAssay Description:Inhibition of human recombinant HDAC8More data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Institute Of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50268121((E)-3-(4-Chloro-2-fluorophenyl)-N-[6-(hydroxyamino...)
Affinity DataIC50:  1.62E+3nMAssay Description:Inhibition of human recombinant HDAC8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Institute Of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50268063((E)-N-[6-(Hydroxyamino)-6-oxohexyl]-3-(7-quinoliny...)
Affinity DataIC50:  2.03E+3nMAssay Description:Inhibition of human recombinant HDAC8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Institute Of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50268042((2E,4E)-N-[6-(Hydroxyamino)-6-oxohexyl]-3-methyl-5...)
Affinity DataIC50:  2.12E+3nMAssay Description:Inhibition of human recombinant HDAC8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed