BindingDB PrimarySearch

Found 33 Enz. Inhib. hit(s) with all data for entry = 50038651

Corticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurogen

Curated by ChEMBL

BDBM50272695(3-(4-chloro-2-morpholinothiazol-5-yl)-2,6-dimethyl...)

Ki: 0.200nMAssay Description:Displacement of [125I]sauvagine from human CRF1 receptor expressed in IMR32 cellsMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

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Corticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurogen

Curated by ChEMBL

BDBM50272638(2-(4-chloro-2,6-dimethoxyphenyl)-4-methoxy-6-methy...)

Ki: 2nMAssay Description:Displacement of [125I]sauvagine from human CRF1 receptor expressed in IMR32 cellsMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

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Corticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurogen

Curated by ChEMBL

BDBM50348828(CHEMBL1628268 | SR-125543A)

Ki: 2nMAssay Description:Displacement of [125I]sauvagine from human CRF1 receptor expressed in IMR32 cellsMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

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Corticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurogen

Curated by ChEMBL

BDBM29442(CHEMBL524616 | Pyrazolo[1,5-a]-1,3,5-triazine, 12-...)

Ki: 2nMAssay Description:Displacement of [125I]sauvagine from human CRF1 receptor expressed in IMR32 cellsMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

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Corticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurogen

Curated by ChEMBL

BDBM50058163(Butyl-[2,5-dimethyl-7-(2,4,6-trimethyl-phenyl)-7H-...)

Ki: 3nMAssay Description:Displacement of [125I]sauvagine from human CRF1 receptor expressed in IMR32 cellsMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

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Corticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurogen

Curated by ChEMBL

BDBM50116105(3-(6-(dimethylamino)-4-methylpyridin-3-yl)-2,5-dim...)

Ki: 3nMAssay Description:Displacement of [125I]sauvagine from human CRF1 receptor expressed in IMR32 cellsMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

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Corticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurogen

Curated by ChEMBL

BDBM50272702(4-methoxy-2-(2-methoxy-4,6-bis(trifluoromethyl)phe...)

Ki: 6nMAssay Description:Displacement of [125I]sauvagine from human CRF1 receptor expressed in IMR32 cellsMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

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Corticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurogen

Curated by ChEMBL

BDBM50231921(1-(2-methoxy-4,6-dimethylphenyl)-3-methyl-N,N-dipr...)

Ki: 6nMAssay Description:Displacement of [125I]sauvagine from human CRF1 receptor expressed in IMR32 cellsMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

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Corticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurogen

Curated by ChEMBL

BDBM50272703(4-methoxy-2-(2-methoxy-4,6-dimethylphenyl)-6-methy...)

Ki: 8nMAssay Description:Displacement of [125I]sauvagine from human CRF1 receptor expressed in IMR32 cellsMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

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Corticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurogen

Curated by ChEMBL

BDBM50272705(2-(4-(difluoromethyl)-2,6-dimethoxyphenyl)-4-metho...)

Ki: 9nMAssay Description:Displacement of [125I]sauvagine from human CRF1 receptor expressed in IMR32 cellsMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

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Corticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurogen

Curated by ChEMBL

BDBM50272704(2-(4-chloro-2,6-dimethoxyphenyl)-4-methoxy-6-methy...)

Ki: 9nMAssay Description:Displacement of [125I]sauvagine from human CRF1 receptor expressed in IMR32 cellsMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

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Corticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurogen

Curated by ChEMBL

BDBM50272750(4-methoxy-2-(2-methoxy-4,6-dimethylphenyl)-6-methy...)

Ki: 15nMAssay Description:Displacement of [125I]sauvagine from human CRF1 receptor expressed in IMR32 cellsMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

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Corticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurogen

Curated by ChEMBL

BDBM50272753(4-ethoxy-2-(2-methoxy-4,6-dimethylphenyl)-6-methyl...)

Ki: 16nMAssay Description:Displacement of [125I]sauvagine from human CRF1 receptor expressed in IMR32 cellsMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

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Corticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurogen

Curated by ChEMBL

BDBM50272636(4-ethyl-6-methoxy-2-(2-methoxy-4,6-dimethylphenyl)...)

Ki: 22nMAssay Description:Displacement of [125I]sauvagine from human CRF1 receptor expressed in IMR32 cellsMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

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Corticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurogen

Curated by ChEMBL

BDBM50272751(4-chloro-2-(2-methoxy-4,6-dimethylphenyl)-6-methyl...)

Ki: 33nMAssay Description:Displacement of [125I]sauvagine from human CRF1 receptor expressed in IMR32 cellsMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

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Corticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurogen

Curated by ChEMBL

BDBM50272754(2-(2-methoxy-4,6-dimethylphenyl)-4-methyl-6-propox...)

Ki: 53nMAssay Description:Displacement of [125I]sauvagine from human CRF1 receptor expressed in IMR32 cellsMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

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Corticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurogen

Curated by ChEMBL

BDBM50272637(4-methoxy-2-(2-methoxy-4,6-dimethylphenyl)-N,N,6-t...)

Ki: 76nMAssay Description:Displacement of [125I]sauvagine from human CRF1 receptor expressed in IMR32 cellsMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

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Corticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurogen

Curated by ChEMBL

BDBM50272640(4-methoxy-2-(2-methoxy-4,6-dimethylphenyl)-6-methy...)

Ki: 94nMAssay Description:Displacement of [125I]sauvagine from human CRF1 receptor expressed in IMR32 cellsMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

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Corticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurogen

Curated by ChEMBL

BDBM50272697(2-(2,6-dimethoxyphenyl)-4-methoxy-6-methyl-N,N-dip...)

Ki: 277nMAssay Description:Displacement of [125I]sauvagine from human CRF1 receptor expressed in IMR32 cellsMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

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Corticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurogen

Curated by ChEMBL

BDBM50272752(2-mesityl-4-methoxy-6-methyl-N,N-dipropylpyrimidin...)

Ki: 354nMAssay Description:Displacement of [125I]sauvagine from human CRF1 receptor expressed in IMR32 cellsMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

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Corticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurogen

Curated by ChEMBL

BDBM50272701(2-(2,4-dimethoxyphenyl)-4-methoxy-6-methyl-N,N-dip...)

Ki: 507nMAssay Description:Displacement of [125I]sauvagine from human CRF1 receptor expressed in IMR32 cellsMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

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Corticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurogen

Curated by ChEMBL

BDBM50272696(2-(2-methoxy-4,6-dimethylphenyl)-4-methyl-N,N-dipr...)

Ki: 561nMAssay Description:Displacement of [125I]sauvagine from human CRF1 receptor expressed in IMR32 cellsMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

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Corticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurogen

Curated by ChEMBL

BDBM50272699(1-(5-(dipropylamino)-6-methoxy-2-(2-methoxy-4,6-di...)

Ki: 604nMAssay Description:Displacement of [125I]sauvagine from human CRF1 receptor expressed in IMR32 cellsMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

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Corticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurogen

Curated by ChEMBL

BDBM50272698(1-(5-(dipropylamino)-6-methoxy-2-(2-methoxy-4,6-di...)

Ki: 1.15E+3nMAssay Description:Displacement of [125I]sauvagine from human CRF1 receptor expressed in IMR32 cellsMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

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Corticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurogen

Curated by ChEMBL

BDBM50272635(2-(5-(dipropylamino)-2-(2-methoxy-4,6-dimethylphen...)

Ki: 1.61E+3nMAssay Description:Displacement of [125I]sauvagine from human CRF1 receptor expressed in IMR32 cellsMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

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Corticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurogen

Curated by ChEMBL

BDBM50272634(4-isopropoxy-2-(2-methoxy-4,6-dimethylphenyl)-6-me...)

Ki: >5.00E+3nMAssay Description:Displacement of [125I]sauvagine from human CRF1 receptor expressed in IMR32 cellsMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

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Corticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurogen

Curated by ChEMBL

BDBM50272639(4-methoxy-2-(2-methoxy-4,6-dimethylphenyl)-6-methy...)

Ki: >1.00E+4nMAssay Description:Displacement of [125I]sauvagine from human CRF1 receptor expressed in IMR32 cellsMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

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Corticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurogen

Curated by ChEMBL

BDBM50272641(4-methoxy-2-(2-methoxy-4,6-dimethylphenyl)-6-methy...)

Ki: >1.00E+4nMAssay Description:Displacement of [125I]sauvagine from human CRF1 receptor expressed in IMR32 cellsMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

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Corticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurogen

Curated by ChEMBL

BDBM50272700(2-(2,4-dichlorophenyl)-4-methoxy-6-methyl-N,N-dipr...)

Ki: >1.00E+4nMAssay Description:Displacement of [125I]sauvagine from human CRF1 receptor expressed in IMR32 cellsMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

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Corticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurogen

Curated by ChEMBL

BDBM50272638(2-(4-chloro-2,6-dimethoxyphenyl)-4-methoxy-6-methy...)

IC50: 1nMAssay Description:Antagonist activity at CRF1 receptor expressed in mouse AtT20 cells assessed as inhibition of sauvagine-stimulated cAMP accumulationMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

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Corticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurogen

Curated by ChEMBL

BDBM50272704(2-(4-chloro-2,6-dimethoxyphenyl)-4-methoxy-6-methy...)

IC50: 7nMAssay Description:Antagonist activity at CRF1 receptor expressed in mouse AtT20 cells assessed as inhibition of sauvagine-stimulated cAMP accumulationMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

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Corticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurogen

Curated by ChEMBL

BDBM50231921(1-(2-methoxy-4,6-dimethylphenyl)-3-methyl-N,N-dipr...)

IC50: 12nMAssay Description:Antagonist activity at CRF1 receptor expressed in mouse AtT20 cells assessed as inhibition of sauvagine-stimulated cAMP accumulationMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

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Corticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurogen

Curated by ChEMBL

BDBM50272703(4-methoxy-2-(2-methoxy-4,6-dimethylphenyl)-6-methy...)

IC50: 19nMAssay Description:Antagonist activity at CRF1 receptor expressed in mouse AtT20 cells assessed as inhibition of sauvagine-stimulated cAMP accumulationMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed