Compile Data Set for Download or QSAR
maximum 50k data
Found 5 Enz. Inhib. hit(s) with all data for entry = 50026932
TargetVitamin D3 receptor(Homo sapiens (Human))
Tokyo Medical And Dental University

Curated by ChEMBL
LigandPNGBDBM50292705((25R)-25-Adamantyl-1alpha,25-dihydroxy-2-methylene...)
Affinity DataIC50:  3nMAssay Description:Antagonist activity at VDR expressed in COS7 cells assessed as inhibition of 1,25-Dihydroxyvitamin D3-induced response by transient transcription ass...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
Tokyo Medical And Dental University

Curated by ChEMBL
LigandPNGBDBM50292704((1R,3R,7E,17beta)-17-{(1S,2E,5R)-5-hydroxy-1-methy...)
Affinity DataIC50:  30nMAssay Description:Antagonist activity at VDR expressed in COS7 cells assessed as inhibition of 1,25-Dihydroxyvitamin D3-induced response by transient transcription ass...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
Tokyo Medical And Dental University

Curated by ChEMBL
LigandPNGBDBM50292706((1R,3R,7E,17beta)-17-{(1R,2E,4R)-4-hydroxy-1-methy...)
Affinity DataEC50:  0.0200nMAssay Description:Agonist activity at VDR assessed as receptor transactivation by transient transcription assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
Tokyo Medical And Dental University

Curated by ChEMBL
LigandPNGBDBM50292704((1R,3R,7E,17beta)-17-{(1S,2E,5R)-5-hydroxy-1-methy...)
Affinity DataEC50:  24nMAssay Description:Agonist activity at VDR assessed as receptor transactivation by transient transcription assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
Tokyo Medical And Dental University

Curated by ChEMBL
LigandPNGBDBM50292705((25R)-25-Adamantyl-1alpha,25-dihydroxy-2-methylene...)
Affinity DataEC50:  1nMAssay Description:Agonist activity at VDR assessed as receptor transactivation by transient transcription assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed