Compile Data Set for Download or QSAR
maximum 50k data
Found 59 Enz. Inhib. hit(s) with all data for entry = 50026984
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50265209(1'-(5-chloro-1H-benzo[d]imidazol-2-yl)-3H-spiro[is...)
Affinity DataIC50:  1.20nMAssay Description:Antagonist activity at human NPY Y5 receptor transfected in mouse LMtk cells assessed as inhibition of neuropeptide Y-induced increase in intercellul...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50264726(1'-(5,6-dichloro-1H-benzo[d]imidazol-2-yl)-3H-spir...)
Affinity DataIC50:  1.40nMAssay Description:Antagonist activity at human NPY Y5 receptor transfected in mouse LMtk cells assessed as inhibition of neuropeptide Y-induced increase in intercellul...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50265298(CHEMBL496327 | methyl 2-(3-oxo-3H-spiro[isobenzofu...)
Affinity DataIC50:  1.5nMAssay Description:Antagonist activity at human NPY Y5 receptor transfected in mouse LMtk cells assessed as inhibition of neuropeptide Y-induced increase in intercellul...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50264726(1'-(5,6-dichloro-1H-benzo[d]imidazol-2-yl)-3H-spir...)
Affinity DataIC50:  1.60nMAssay Description:Binding affinity to human NPY Y5 receptor transfected in mouse LMtk cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50265267(1'-(5-phenyl-1H-benzo[d]imidazol-2-yl)-3H-spiro[is...)
Affinity DataIC50:  1.80nMAssay Description:Antagonist activity at human NPY Y5 receptor transfected in mouse LMtk cells assessed as inhibition of neuropeptide Y-induced increase in intercellul...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50265297(1'-(5-isobutyl-1H-benzo[d]imidazol-2-yl)-3H-spiro[...)
Affinity DataIC50:  1.80nMAssay Description:Binding affinity to human NPY Y5 receptor transfected in mouse LMtk cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50265299(CHEMBL524644 | ethyl 2-(3-oxo-3H-spiro[isobenzofur...)
Affinity DataIC50:  2nMAssay Description:Binding affinity to human NPY Y5 receptor transfected in mouse LMtk cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50264853(1'-(2,2-difluoro-5H-[1,3]dioxolo[4,5-f]benzimidazo...)
Affinity DataIC50:  2.20nMAssay Description:Binding affinity to human NPY Y5 receptor transfected in mouse LMtk cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50265267(1'-(5-phenyl-1H-benzo[d]imidazol-2-yl)-3H-spiro[is...)
Affinity DataIC50:  2.40nMAssay Description:Binding affinity to human NPY Y5 receptor transfected in mouse LMtk cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50265298(CHEMBL496327 | methyl 2-(3-oxo-3H-spiro[isobenzofu...)
Affinity DataIC50:  2.70nMAssay Description:Binding affinity to human NPY Y5 receptor transfected in mouse LMtk cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50265265(1'-(5-(trifluoromethyl)-1H-benzo[d]imidazol-2-yl)-...)
Affinity DataIC50:  3.5nMAssay Description:Binding affinity to human NPY Y5 receptor transfected in mouse LMtk cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50264728(1'-(5,6-difluoro-1H-benzo[d]imidazol-2-yl)-3H-spir...)
Affinity DataIC50:  4.80nMAssay Description:Binding affinity to human NPY Y5 receptor transfected in mouse LMtk cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50264725(1'-(4,6-dichloro-1H-benzo[d]imidazol-2-yl)-3H-spir...)
Affinity DataIC50:  5.70nMAssay Description:Binding affinity to human NPY Y5 receptor transfected in mouse LMtk cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50265209(1'-(5-chloro-1H-benzo[d]imidazol-2-yl)-3H-spiro[is...)
Affinity DataIC50:  6.60nMAssay Description:Binding affinity to human NPY Y5 receptor transfected in mouse LMtk cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50264766(1'-(5-chloro-6-fluoro-1H-benzo[d]imidazol-2-yl)-3H...)
Affinity DataIC50:  6.70nMAssay Description:Binding affinity to human NPY Y5 receptor transfected in mouse LMtk cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50264727(1'-(5,6-dimethyl-1H-benzo[d]imidazol-2-yl)-3H-spir...)
Affinity DataIC50:  9.20nMAssay Description:Binding affinity to human NPY Y5 receptor transfected in mouse LMtk cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50264852(1'-(5H-[1,3]dioxolo[4,5-f]benzimidazol-6-yl)-3H-sp...)
Affinity DataIC50:  9.30nMAssay Description:Binding affinity to human NPY Y5 receptor transfected in mouse LMtk cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50265268(1'-(5-bromo-1H-benzo[d]imidazol-2-yl)-3H-spiro[iso...)
Affinity DataIC50:  10nMAssay Description:Binding affinity to human NPY Y5 receptor transfected in mouse LMtk cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50265269(1'-(5-nitro-1H-benzo[d]imidazol-2-yl)-3H-spiro[iso...)
Affinity DataIC50:  10nMAssay Description:Binding affinity to human NPY Y5 receptor transfected in mouse LMtk cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50265266(1'-(4-phenyl-1H-benzo[d]imidazol-2-yl)-3H-spiro[is...)
Affinity DataIC50:  17nMAssay Description:Binding affinity to human NPY Y5 receptor transfected in mouse LMtk cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50265296(2-(3-oxo-3H-spiro[isobenzofuran-1,4'-piperidine]-1...)
Affinity DataIC50:  19nMAssay Description:Binding affinity to human NPY Y5 receptor transfected in mouse LMtk cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50265336(CHEMBL525908 | N-methyl-2-(3-oxo-3H-spiro[isobenzo...)
Affinity DataIC50:  20nMAssay Description:Binding affinity to human NPY Y5 receptor transfected in mouse LMtk cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50265167(1'-(5-fluoro-1H-benzo[d]imidazol-2-yl)-3H-spiro[is...)
Affinity DataIC50:  28nMAssay Description:Binding affinity to human NPY Y5 receptor transfected in mouse LMtk cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50265169(1'-(5-methyl-1H-benzo[d]imidazol-2-yl)-3H-spiro[is...)
Affinity DataIC50:  36nMAssay Description:Binding affinity to human NPY Y5 receptor transfected in mouse LMtk cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50265207(1'-(5-methoxy-1H-benzo[d]imidazol-2-yl)-3H-spiro[i...)
Affinity DataIC50:  37nMAssay Description:Binding affinity to human NPY Y5 receptor transfected in mouse LMtk cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50265208(1'-(4-chloro-1H-benzo[d]imidazol-2-yl)-3H-spiro[is...)
Affinity DataIC50:  51nMAssay Description:Binding affinity to human NPY Y5 receptor transfected in mouse LMtk cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50265340(CHEMBL496537 | N-(2-(3-oxo-3H-spiro[isobenzofuran-...)
Affinity DataIC50:  56nMAssay Description:Binding affinity to human NPY Y5 receptor transfected in mouse LMtk cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50265337(CHEMBL497785 | N,N-dimethyl-2-(3-oxo-3H-spiro[isob...)
Affinity DataIC50:  58nMAssay Description:Binding affinity to human NPY Y5 receptor transfected in mouse LMtk cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50265168(1'-(4-methyl-1H-benzo[d]imidazol-2-yl)-3H-spiro[is...)
Affinity DataIC50:  74nMAssay Description:Binding affinity to human NPY Y5 receptor transfected in mouse LMtk cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50265210(1'-(4-(trifluoromethyl)-1H-benzo[d]imidazol-2-yl)-...)
Affinity DataIC50:  83nMAssay Description:Binding affinity to human NPY Y5 receptor transfected in mouse LMtk cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50264724(1'-(5-(methylsulfonyl)-1H-benzo[d]imidazol-2-yl)-3...)
Affinity DataIC50:  85nMAssay Description:Binding affinity to human NPY Y5 receptor transfected in mouse LMtk cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50265128(CHEMBL495930 | trans-4-(3H-imidazo[4,5-b]pyridin-2...)
Affinity DataIC50:  91nMAssay Description:Binding affinity to human NPY Y5 receptor transfected in mouse LMtk cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50265300(2-(3-oxo-3H-spiro[isobenzofuran-1,4'-piperidine]-1...)
Affinity DataIC50:  110nMAssay Description:Binding affinity to human NPY Y5 receptor transfected in mouse LMtk cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50265339(CHEMBL497786 | N-(2-(3-oxo-3H-spiro[isobenzofuran-...)
Affinity DataIC50:  130nMAssay Description:Binding affinity to human NPY Y5 receptor transfected in mouse LMtk cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50265124(1'-(1H-benzo[d]imidazol-2-yl)-3H-spiro[isobenzofur...)
Affinity DataIC50:  140nMAssay Description:Binding affinity to human NPY Y5 receptor transfected in mouse LMtk cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50265206(1'-(4-methoxy-1H-benzo[d]imidazol-2-yl)-3H-spiro[i...)
Affinity DataIC50:  250nMAssay Description:Binding affinity to human NPY Y5 receptor transfected in mouse LMtk cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50265166(1'-(4-fluoro-1H-benzo[d]imidazol-2-yl)-3H-spiro[is...)
Affinity DataIC50:  500nMAssay Description:Binding affinity to human NPY Y5 receptor transfected in mouse LMtk cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50265338(2-(3-oxo-3H-spiro[isobenzofuran-1,4'-piperidine]-1...)
Affinity DataIC50: >1.00E+3nMAssay Description:Binding affinity to human NPY Y5 receptor transfected in mouse LMtk cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50265088(2-(1-(methylsulfonyl)spiro[indoline-3,4'-piperidin...)
Affinity DataIC50: >1.00E+3nMAssay Description:Binding affinity to human NPY Y5 receptor transfected in mouse LMtk cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50265165(CHEMBL498197 | cis-4-(3H-imidazo[4,5-b]pyridin-2-y...)
Affinity DataIC50:  1.40E+3nMAssay Description:Binding affinity to human NPY Y5 receptor transfected in mouse LMtk cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50265126(1'-(3H-imidazo[4,5-b]pyridin-2-yl)-3H-spiro[isoben...)
Affinity DataIC50:  1.60E+3nMAssay Description:Binding affinity to human NPY Y5 receptor transfected in mouse LMtk cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50265127(1'-((1H-benzo[d]imidazol-2-yl)methyl)-3H-spiro[iso...)
Affinity DataIC50:  4.90E+3nMAssay Description:Binding affinity to human NPY Y5 receptor transfected in mouse LMtk cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50265265(1'-(5-(trifluoromethyl)-1H-benzo[d]imidazol-2-yl)-...)
Affinity DataIC50:  6.40E+3nMAssay Description:Antagonist activity at human NPY Y5 receptor transfected in mouse LMtk cells assessed as inhibition of neuropeptide Y-induced increase in intercellul...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50265265(1'-(5-(trifluoromethyl)-1H-benzo[d]imidazol-2-yl)-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to NPY Y4 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50265267(1'-(5-phenyl-1H-benzo[d]imidazol-2-yl)-3H-spiro[is...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to NPY Y4 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50265298(CHEMBL496327 | methyl 2-(3-oxo-3H-spiro[isobenzofu...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to NPY Y4 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50264726(1'-(5,6-dichloro-1H-benzo[d]imidazol-2-yl)-3H-spir...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to NPY Y4 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50265298(CHEMBL496327 | methyl 2-(3-oxo-3H-spiro[isobenzofu...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to NPY Y1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50265267(1'-(5-phenyl-1H-benzo[d]imidazol-2-yl)-3H-spiro[is...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to NPY Y1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50265265(1'-(5-(trifluoromethyl)-1H-benzo[d]imidazol-2-yl)-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to NPY Y1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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