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Found 21 Enz. Inhib. hit(s) with all data for entry = 2797
TargetGenome polyprotein [1424-1463]/[1502-1685](West Nile virus (WNV))
University Of Queensland

LigandPNGBDBM24732((2S)-6-amino-N-[(1S)-5-amino-1-{[(2S)-5-carbamimid...)
Affinity DataKi:  6nM ΔG°:  -48.8kJ/mole IC50:  32nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1424-1463]/[1502-1685](West Nile virus (WNV))
University Of Queensland

LigandPNGBDBM24731((2S)-6-amino-N-[(1S)-5-amino-1-{[(2S)-5-carbamimid...)
Affinity DataKi:  9nM ΔG°:  -47.8kJ/mole IC50:  51nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1424-1463]/[1502-1685](West Nile virus (WNV))
University Of Queensland

LigandPNGBDBM24734((2S)-6-amino-N-[(1S)-5-amino-1-{[(2S)-5-carbamimid...)
Affinity DataKi:  11nM ΔG°:  -47.3kJ/mole IC50:  60nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1424-1463]/[1502-1685](West Nile virus (WNV))
University Of Queensland

LigandPNGBDBM24746((2S)-6-amino-N-[(1S)-4-amino-1-{[(2S)-5-carbamimid...)
Affinity DataKi:  13nM ΔG°:  -46.8kJ/mole IC50:  73nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1424-1463]/[1502-1685](West Nile virus (WNV))
University Of Queensland

LigandPNGBDBM24739((2S)-6-amino-N-[(1S)-5-amino-1-{[(2S)-5-carbamimid...)
Affinity DataKi:  19nM ΔG°:  -45.8kJ/mole IC50:  107nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1424-1463]/[1502-1685](West Nile virus (WNV))
University Of Queensland

LigandPNGBDBM24733((2S)-6-amino-N-[(1S)-5-amino-1-{[(2S)-5-carbamimid...)
Affinity DataKi:  20nM ΔG°:  -45.7kJ/mole IC50:  112nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1424-1463]/[1502-1685](West Nile virus (WNV))
University Of Queensland

LigandPNGBDBM24735((2S)-6-amino-N-[(1S)-5-amino-1-{[(2S)-5-carbamimid...)
Affinity DataKi:  26nM ΔG°:  -45.0kJ/mole IC50:  146nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1424-1463]/[1502-1685](West Nile virus (WNV))
University Of Queensland

LigandPNGBDBM24741((2S)-6-amino-N-[(2S)-5-carbamimidamido-1-oxopentan...)
Affinity DataKi:  28nM ΔG°:  -44.8kJ/mole IC50:  154nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1424-1463]/[1502-1685](West Nile virus (WNV))
University Of Queensland

LigandPNGBDBM24736(Capped tripeptide aldehyde inhibitor, 24 | benzyl ...)
Affinity DataKi:  40nM ΔG°:  -43.9kJ/mole IC50:  222nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1424-1463]/[1502-1685](West Nile virus (WNV))
University Of Queensland

LigandPNGBDBM24728((2S)-6-amino-N-[(1S)-5-amino-1-{[(2S)-5-carbamimid...)
Affinity DataKi:  41nM ΔG°:  -43.9kJ/mole IC50:  231nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
TargetGenome polyprotein [1424-1463]/[1502-1685](West Nile virus (WNV))
University Of Queensland

LigandPNGBDBM24744((2S)-N-[(1S)-5-amino-1-{[(2S)-5-carbamimidamido-1-...)
Affinity DataKi:  44nM ΔG°:  -43.7kJ/mole IC50:  245nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1424-1463]/[1502-1685](West Nile virus (WNV))
University Of Queensland

LigandPNGBDBM24742((2S)-6-amino-2-[(2S)-5-amino-2-(1-phenylacetamido)...)
Affinity DataKi:  46nM ΔG°:  -43.6kJ/mole IC50:  255nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1424-1463]/[1502-1685](West Nile virus (WNV))
University Of Queensland

LigandPNGBDBM24737((2S)-6-amino-N-[(1S)-5-amino-1-{[(2S)-5-carbamimid...)
Affinity DataKi:  49nM ΔG°:  -43.4kJ/mole IC50:  271nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1424-1463]/[1502-1685](West Nile virus (WNV))
University Of Queensland

LigandPNGBDBM24748((2S)-2-[(2S)-6-amino-2-(1-phenylacetamido)hexanami...)
Affinity DataKi:  53nM ΔG°:  -43.2kJ/mole IC50:  297nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1424-1463]/[1502-1685](West Nile virus (WNV))
University Of Queensland

LigandPNGBDBM24745((2S)-6-amino-N-[(1S)-4-carbamimidamido-1-{[(2S)-5-...)
Affinity DataKi:  58nM ΔG°:  -43.0kJ/mole IC50:  325nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1424-1463]/[1502-1685](West Nile virus (WNV))
University Of Queensland

LigandPNGBDBM24738((2S)-6-amino-N-[(1S)-5-amino-1-{[(2S)-5-carbamimid...)
Affinity DataKi:  81nM ΔG°:  -42.1kJ/mole IC50:  454nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1424-1463]/[1502-1685](West Nile virus (WNV))
University Of Queensland

LigandPNGBDBM24730((2S)-6-amino-2-[(2S)-6-amino-2-[(2E)-3-phenylprop-...)
Affinity DataKi:  104nM ΔG°:  -41.5kJ/mole IC50:  580nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1424-1463]/[1502-1685](West Nile virus (WNV))
University Of Queensland

LigandPNGBDBM24743((2S)-6-amino-N-[(2S)-5-carbamimidamido-1-oxopentan...)
Affinity DataKi:  111nM ΔG°:  -41.3kJ/mole IC50:  619nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1424-1463]/[1502-1685](West Nile virus (WNV))
University Of Queensland

LigandPNGBDBM24740((2S)-6-amino-N-[(1S)-5-amino-1-{[(2S)-5-carbamimid...)
Affinity DataKi:  160nM ΔG°:  -40.3kJ/mole IC50:  891nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1424-1463]/[1502-1685](West Nile virus (WNV))
University Of Queensland

LigandPNGBDBM24747((2S)-6-amino-N-[(1S)-1-{[(2S)-5-carbamimidamido-1-...)
Affinity DataKi:  2.07E+3nM ΔG°:  -33.7kJ/mole IC50:  1.16E+4nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1424-1463]/[1502-1685](West Nile virus (WNV))
University Of Queensland

LigandPNGBDBM24749((2S)-6-amino-N-[(1S)-5-amino-1-{[(2S)-1-(1H-indol-...)
Affinity DataKi:  4.60E+3nM ΔG°:  -31.7kJ/mole IC50:  2.57E+4nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed