Affinity DataIC50: 1nMAssay Description:Inhibition of human adrenal corticoid CYP11B2 expressed in chinese hamster V79 MZh cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.70nMAssay Description:Inhibition of human adrenal corticoid CYP11B2 expressed in chinese hamster V79 MZh cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of human adrenal corticoid CYP11B2 expressed in chinese hamster V79 MZh cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.90nMAssay Description:Inhibition of human adrenal corticoid CYP11B2 expressed in chinese hamster V79 MZh cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of human adrenal corticoid CYP11B2 expressed in chinese hamster V79 MZh cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 6.20nMAssay Description:Inhibition of human adrenal corticoid CYP11B2 expressed in chinese hamster V79 MZh cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of human adrenal corticoid CYP11B1 expressed in chinese hamster V79 MZh cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 7.60nMAssay Description:Inhibition of human adrenal corticoid CYP11B2 expressed in chinese hamster V79 MZh cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 7.70nMAssay Description:Inhibition of human adrenal corticoid CYP11B2 expressed in chinese hamster V79 MZh cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 7.80nMAssay Description:Inhibition of human adrenal corticoid CYP11B2 expressed in chinese hamster V79 MZh cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human adrenal corticoid CYP11B1 expressed in chinese hamster V79 MZh cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of human adrenal corticoid CYP11B2 expressed in chinese hamster V79 MZh cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of human adrenal corticoid CYP11B2 expressed in chinese hamster V79 MZh cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of human adrenal corticoid CYP11B1 expressed in chinese hamster V79 MZh cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant CYP2D6 expressed in baculovirus-infected insect microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of human adrenal corticoid CYP11B2 expressed in chinese hamster V79 MZh cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of human adrenal corticoid CYP11B2 expressed in chinese hamster V79 MZh cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibition of human adrenal corticoid CYP11B1 expressed in chinese hamster V79 MZh cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of human adrenal corticoid CYP11B2 expressed in chinese hamster V79 MZh cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of human adrenal corticoid CYP11B2 expressed in chinese hamster V79 MZh cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of human adrenal corticoid CYP11B2 expressed in chinese hamster V79 MZh cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of human adrenal corticoid CYP11B2 expressed in chinese hamster V79 MZh cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of human placental microsome CYP19More data for this Ligand-Target Pair
Affinity DataIC50: 38nMAssay Description:Inhibition of human placental microsome CYP19More data for this Ligand-Target Pair
Affinity DataIC50: 53nMAssay Description:Inhibition of human adrenal corticoid CYP11B2 expressed in chinese hamster V79 MZh cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 64nMAssay Description:Inhibition of human recombinant CYP2C9 expressed in baculovirus-infected insect microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 65nMAssay Description:Inhibition of human adrenal corticoid CYP11B2 expressed in chinese hamster V79 MZh cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 79nMAssay Description:Inhibition of human adrenal corticoid CYP11B1 expressed in chinese hamster V79 MZh cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 95nMAssay Description:Inhibition of human adrenal corticoid CYP11B2 expressed in chinese hamster V79 MZh cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 119nMAssay Description:Inhibition of human adrenal corticoid CYP11B2 expressed in chinese hamster V79 MZh cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 124nMAssay Description:Inhibition of human adrenal corticoid CYP11B2 expressed in chinese hamster V79 MZh cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 152nMAssay Description:Inhibition of human adrenal corticoid CYP11B1 expressed in chinese hamster V79 MZh cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 154nMAssay Description:Inhibition of human adrenal corticoid CYP11B2 expressed in chinese hamster V79 MZh cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 187nMAssay Description:Inhibition of human adrenal corticoid CYP11B2 expressed in chinese hamster V79 MZh cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 187nMAssay Description:Inhibition of human adrenal corticoid CYP11B1 expressed in chinese hamster V79 MZh cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 318nMAssay Description:Inhibition of human recombinant CYP2C9 expressed in baculovirus-infected insect microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 640nMAssay Description:Inhibition of human adrenal corticoid CYP11B1 expressed in chinese hamster V79 MZh cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 735nMAssay Description:Inhibition of human adrenal corticoid CYP11B1 expressed in chinese hamster V79 MZh cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 785nMAssay Description:Inhibition of human adrenal corticoid CYP11B1 expressed in chinese hamster V79 MZh cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 953nMAssay Description:Inhibition of human adrenal corticoid CYP11B1 expressed in chinese hamster V79 MZh cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.58E+3nMAssay Description:Inhibition of human adrenal corticoid CYP11B1 expressed in chinese hamster V79 MZh cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.81E+3nMAssay Description:Inhibition of human adrenal corticoid CYP11B1 expressed in chinese hamster V79 MZh cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.96E+3nMAssay Description:Inhibition of human adrenal corticoid CYP11B1 expressed in chinese hamster V79 MZh cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.42E+3nMAssay Description:Inhibition of human recombinant CYP1A2 expressed in baculovirus-infected insect microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 2.45E+3nMAssay Description:Inhibition of human adrenal corticoid CYP11B1 expressed in chinese hamster V79 MZh cellsMore data for this Ligand-Target Pair
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University
Curated by ChEMBL
Saarland University
Curated by ChEMBL
Affinity DataIC50: 2.78E+3nMAssay Description:Inhibition of human recombinant CYP17 expressed in Escherichia coli pJL17/ORMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of human adrenal corticoid CYP11B1 expressed in chinese hamster V79 MZh cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.94E+3nMAssay Description:Inhibition of human adrenal corticoid CYP11B1 expressed in chinese hamster V79 MZh cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.56E+3nMAssay Description:Inhibition of human adrenal corticoid CYP11B1 expressed in chinese hamster V79 MZh cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 4.33E+3nMAssay Description:Inhibition of human adrenal corticoid CYP11B1 expressed in chinese hamster V79 MZh cellsMore data for this Ligand-Target Pair