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Found 26 Enz. Inhib. hit(s) with all data for entry = 50038682
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50260153(Apamin | CHEMBL525408 | Octadecapeptide venom)
Affinity DataIC50:  0.0640nMAssay Description:Inhibition of Kca2.3 channel expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50260153(Apamin | CHEMBL525408 | Octadecapeptide venom)
Affinity DataIC50:  0.168nMAssay Description:Inhibition of Kca2.3 channel expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50263327(CHEMBL476339 | N-(4-methylpyridin-2-yl)-4-(pyridin...)
Affinity DataIC50:  4nMAssay Description:Displacement of [125I]apamin from Kca2.3 channel expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50263327(CHEMBL476339 | N-(4-methylpyridin-2-yl)-4-(pyridin...)
Affinity DataIC50:  4nMAssay Description:Inhibition of Kca2.1 channel expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50263327(CHEMBL476339 | N-(4-methylpyridin-2-yl)-4-(pyridin...)
Affinity DataIC50:  11nMAssay Description:Inhibition of Kca2.2 channel expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50264020(CHEMBL489770 | GNF-PF-4773 | N-(4-(pyridin-2-yl)th...)
Affinity DataIC50:  25nMAssay Description:Displacement of [125I]apamin from Kca2.3 channel expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50264020(CHEMBL489770 | GNF-PF-4773 | N-(4-(pyridin-2-yl)th...)
Affinity DataIC50:  43nMAssay Description:Inhibition of Kca2.1 channel expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50263327(CHEMBL476339 | N-(4-methylpyridin-2-yl)-4-(pyridin...)
Affinity DataIC50:  56nMAssay Description:Inhibition of Kca2.3 channel expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50263327(CHEMBL476339 | N-(4-methylpyridin-2-yl)-4-(pyridin...)
Affinity DataIC50:  59nMAssay Description:Displacement of [125I]apamin from Kca2.2 channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50263327(CHEMBL476339 | N-(4-methylpyridin-2-yl)-4-(pyridin...)
Affinity DataIC50:  59nMAssay Description:Inhibition of Kca2.3 channel expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50264020(CHEMBL489770 | GNF-PF-4773 | N-(4-(pyridin-2-yl)th...)
Affinity DataIC50:  123nMAssay Description:Inhibition of Kca2.2 channel expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50264020(CHEMBL489770 | GNF-PF-4773 | N-(4-(pyridin-2-yl)th...)
Affinity DataIC50:  290nMAssay Description:Inhibition of Kca2.3 channel expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50264020(CHEMBL489770 | GNF-PF-4773 | N-(4-(pyridin-2-yl)th...)
Affinity DataIC50:  543nMAssay Description:Displacement of [125I]apamin from Kca2.2 channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50264020(CHEMBL489770 | GNF-PF-4773 | N-(4-(pyridin-2-yl)th...)
Affinity DataIC50:  543nMAssay Description:Inhibition of Kca2.3 channel expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50048403(1,1'-(Deca-4,6-diyne-1,10-diyl)bis(4-amino-2-methy...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of Kca2.3 channel expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50048403(1,1'-(Deca-4,6-diyne-1,10-diyl)bis(4-amino-2-methy...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of Kca2.3 channel expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50264073(CHEMBL490592 | N-Phenyl-4-(2-pyridinyl)-1,3-thiazo...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Kca2.3 channel expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50264072(2-(2-(pyridin-2-ylmethyl)thiazol-4-yl)pyridine | C...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Kca2.3 channel expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50264071(CHEMBL452409 | N-(4-(pyridin-4-yl)thiazol-2-yl)pyr...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Kca2.3 channel expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50264070(CHEMBL492010 | N-(4-(pyridin-3-yl)thiazol-2-yl)pyr...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Kca2.3 channel expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50264074(CHEMBL510166 | N,4-Diphenylthiazol-2-amine)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Kca2.3 channel expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50264076(CHEMBL503704 | N-(4-(pyridin-2-yl)thiazol-2-yl)pyr...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Kca2.3 channel expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50263326(3-chloro-N-(4-(pyridin-2-yl)thiazol-2-yl)-5-(trifl...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Kca2.3 channel expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50264019(5-iodo-N-(4-(pyridin-2-yl)thiazol-2-yl)pyridin-2-a...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Kca2.3 channel expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50264021(CHEMBL491603 | N-(4-(pyridin-2-yl)thiazol-2-yl)pyr...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Kca2.3 channel expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50264075(2-(4-(pyridin-2-yl)thiazol-2-yl)pyridine | CHEMBL5...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Kca2.3 channel expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed