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Found 15 Enz. Inhib. hit(s) with all data for entry = 50038704
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Albert Einstein College Of Medicine Of Yeshiva University

Curated by ChEMBL
LigandPNGBDBM50246593(7-((1,3-dihydroxypropan-2-ylamino)methyl)-3H-pyrro...)
Affinity DataKi:  0.00520nMAssay Description:Equilibrium binding affinity to wild type human PNPMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Albert Einstein College Of Medicine Of Yeshiva University

Curated by ChEMBL
LigandPNGBDBM50246590(7-(((3R,4S)-3-hydroxy-4-(propylthiomethyl)pyrrolid...)
Affinity DataKi:  0.00980nMAssay Description:Equilibrium binding affinity to wild type human PNPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Albert Einstein College Of Medicine Of Yeshiva University

Curated by ChEMBL
LigandPNGBDBM22109(7-{[(3R,4R)-3-hydroxy-4-(hydroxymethyl)pyrrolidin-...)
Affinity DataKi:  0.0107nMAssay Description:Equilibrium binding affinity to wild type human PNPMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Albert Einstein College Of Medicine Of Yeshiva University

Curated by ChEMBL
LigandPNGBDBM50247151(7-(((3R,4S)-3-hydroxy-4-(methylthiomethyl)pyrrolid...)
Affinity DataKi:  0.0196nMAssay Description:Equilibrium binding affinity to wild type human PNPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Albert Einstein College Of Medicine Of Yeshiva University

Curated by ChEMBL
LigandPNGBDBM50195587(1,4-DIDEOXY-4-AZA-1-(S)-(9-DEAZAHYPOXANTHIN-9-YL)-...)
Affinity DataKi:  0.0579nMAssay Description:Equilibrium binding affinity to wild type human PNPMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Albert Einstein College Of Medicine Of Yeshiva University

Curated by ChEMBL
LigandPNGBDBM50247151(7-(((3R,4S)-3-hydroxy-4-(methylthiomethyl)pyrrolid...)
Affinity DataKi:  0.100nMAssay Description:Initial binding affinity to wild type human PNPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Albert Einstein College Of Medicine Of Yeshiva University

Curated by ChEMBL
LigandPNGBDBM50246593(7-((1,3-dihydroxypropan-2-ylamino)methyl)-3H-pyrro...)
Affinity DataKi:  0.110nMAssay Description:Initial binding affinity to wild type human PNPMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Albert Einstein College Of Medicine Of Yeshiva University

Curated by ChEMBL
LigandPNGBDBM50246590(7-(((3R,4S)-3-hydroxy-4-(propylthiomethyl)pyrrolid...)
Affinity DataKi:  0.117nMAssay Description:Initial binding affinity to wild type human PNPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Albert Einstein College Of Medicine Of Yeshiva University

Curated by ChEMBL
LigandPNGBDBM22109(7-{[(3R,4R)-3-hydroxy-4-(hydroxymethyl)pyrrolidin-...)
Affinity DataKi:  1.10nMAssay Description:Initial binding affinity to wild type human PNPMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Albert Einstein College Of Medicine Of Yeshiva University

Curated by ChEMBL
LigandPNGBDBM50195587(1,4-DIDEOXY-4-AZA-1-(S)-(9-DEAZAHYPOXANTHIN-9-YL)-...)
Affinity DataKi:  3.30nMAssay Description:Initial binding affinity to wild type human PNPMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Albert Einstein College Of Medicine Of Yeshiva University

Curated by ChEMBL
LigandPNGBDBM50246594((+/-)-7-((1-hydroxy-3-(methylthio)propan-2-ylamino...)
Affinity DataKi:  4.30nMAssay Description:Initial binding affinity to wild type human PNPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Albert Einstein College Of Medicine Of Yeshiva University

Curated by ChEMBL
LigandPNGBDBM50246591((+/-)-5'-deoxy-4'-fluoro-5'-methylthio-DADMe-ImmH ...)
Affinity DataKi:  5.80nMAssay Description:Initial binding affinity to wild type human PNPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Albert Einstein College Of Medicine Of Yeshiva University

Curated by ChEMBL
LigandPNGBDBM50246592(5'-deoxy-4'-hydroxy-5'-methylthio-DADMe-ImmH | CHE...)
Affinity DataKi:  7.90nMAssay Description:Initial binding affinity to wild type human PNPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Albert Einstein College Of Medicine Of Yeshiva University

Curated by ChEMBL
LigandPNGBDBM50247149(5'-Methylthio-ImmH | CHEMBL473929 | US9290501, (A))
Affinity DataKi:  101nMAssay Description:Initial binding affinity to wild type human PNPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Albert Einstein College Of Medicine Of Yeshiva University

Curated by ChEMBL
LigandPNGBDBM50247150(5'-phenylthio-ImmH | CHEMBL474328 | US9290501, (B))
Affinity DataKi:  160nMAssay Description:Initial binding affinity to wild type human PNPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed