Compile Data Set for Download or QSAR
maximum 50k data
Found 32 Enz. Inhib. hit(s) with all data for entry = 50027368
TargetEstrogen receptor beta(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50275964(4-{8-Fluoro-5-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl...)
Affinity DataIC50:  0.700nMAssay Description:Displacement of fluorescein labeled estradiol from human recombinant ERbeta expressed in baculovirus infected insect cells by fluorescence polarizati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50275861(4-{5-[4-(2-Pyrrolidin-1-yl-ethoxy)-phenyl]-2,3-dih...)
Affinity DataIC50:  1.90nMAssay Description:Displacement of fluorescein labeled estradiol from human recombinant ERalpha expressed in baculovirus infected insect cells by fluorescence polarizat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50275918(4-(4-Hydroxyphenyl)-5-[4-(2-pyrrolidin-1-yl-ethoxy...)
Affinity DataIC50:  2.90nMAssay Description:Displacement of fluorescein labeled estradiol from human recombinant ERbeta expressed in baculovirus infected insect cells by fluorescence polarizati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50275917(4-{8-Methoxy-5-[4-(2-piperidin-1-yl-ethoxy)-phenyl...)
Affinity DataIC50:  3.63nMAssay Description:Displacement of fluorescein labeled estradiol from human recombinant ERbeta expressed in baculovirus infected insect cells by fluorescence polarizati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50275916(4-{8-Methoxy-5-[4-(2-pyrrolidin-1-yl-ethoxy)-pheny...)
Affinity DataIC50:  4.61nMAssay Description:Displacement of fluorescein labeled estradiol from human recombinant ERbeta expressed in baculovirus infected insect cells by fluorescence polarizati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50276005(CHEMBL472468 | [4-{8-Fluoro-4-[4-(2-pyrrolidin-1-y...)
Affinity DataIC50:  5.57nMAssay Description:Displacement of fluorescein labeled estradiol from human recombinant ERalpha expressed in baculovirus infected insect cells by fluorescence polarizat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50275861(4-{5-[4-(2-Pyrrolidin-1-yl-ethoxy)-phenyl]-2,3-dih...)
Affinity DataIC50:  5.90nMAssay Description:Displacement of fluorescein labeled estradiol from human recombinant ERbeta expressed in baculovirus infected insect cells by fluorescence polarizati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50275965(3-{8-Fluoro-5-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl...)
Affinity DataIC50:  6nMAssay Description:Displacement of fluorescein labeled estradiol from human recombinant ERbeta expressed in baculovirus infected insect cells by fluorescence polarizati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50276004(4-{8-Fluoro-5-[4-(2-piperidin-1-yl-ethoxy)-phenyl]...)
Affinity DataIC50:  6.5nMAssay Description:Displacement of fluorescein labeled estradiol from human recombinant ERalpha expressed in baculovirus infected insect cells by fluorescence polarizat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50275916(4-{8-Methoxy-5-[4-(2-pyrrolidin-1-yl-ethoxy)-pheny...)
Affinity DataIC50:  6.70nMAssay Description:Displacement of fluorescein labeled estradiol from human recombinant ERalpha expressed in baculovirus infected insect cells by fluorescence polarizat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50275918(4-(4-Hydroxyphenyl)-5-[4-(2-pyrrolidin-1-yl-ethoxy...)
Affinity DataIC50:  8.40nMAssay Description:Displacement of fluorescein labeled estradiol from human recombinant ERalpha expressed in baculovirus infected insect cells by fluorescence polarizat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50275860(1-{2-[4-(4-Phenyl-2,3-dihydro-benzo[b]oxepin-5-yl)...)
Affinity DataIC50:  8.77nMAssay Description:Displacement of fluorescein labeled estradiol from human recombinant ERalpha expressed in baculovirus infected insect cells by fluorescence polarizat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50276004(4-{8-Fluoro-5-[4-(2-piperidin-1-yl-ethoxy)-phenyl]...)
Affinity DataIC50:  8.78nMAssay Description:Displacement of fluorescein labeled estradiol from human recombinant ERbeta expressed in baculovirus infected insect cells by fluorescence polarizati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50275917(4-{8-Methoxy-5-[4-(2-piperidin-1-yl-ethoxy)-phenyl...)
Affinity DataIC50:  10.3nMAssay Description:Displacement of fluorescein labeled estradiol from human recombinant ERalpha expressed in baculovirus infected insect cells by fluorescence polarizat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50275964(4-{8-Fluoro-5-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl...)
Affinity DataIC50:  10.4nMAssay Description:Displacement of fluorescein labeled estradiol from human recombinant ERalpha expressed in baculovirus infected insect cells by fluorescence polarizat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50275965(3-{8-Fluoro-5-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl...)
Affinity DataIC50:  14nMAssay Description:Displacement of fluorescein labeled estradiol from human recombinant ERalpha expressed in baculovirus infected insect cells by fluorescence polarizat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50275919(1-{2-[4-(8-Fluoro-4-phenyl-2,3-dihydro-benzo[b]oxe...)
Affinity DataIC50:  16.2nMAssay Description:Displacement of fluorescein labeled estradiol from human recombinant ERalpha expressed in baculovirus infected insect cells by fluorescence polarizat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50276005(CHEMBL472468 | [4-{8-Fluoro-4-[4-(2-pyrrolidin-1-y...)
Affinity DataIC50:  17.3nMAssay Description:Displacement of fluorescein labeled estradiol from human recombinant ERbeta expressed in baculovirus infected insect cells by fluorescence polarizati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM20608(4-Hydroxytamoxifen | 4-Hydroxytamoxifen (9) | 4-[(...)
Affinity DataIC50:  20nMAssay Description:Displacement of fluorescein labeled estradiol from human recombinant ERbeta expressed in baculovirus infected insect cells by fluorescence polarizati...More data for this Ligand-Target Pair
TargetEstrogen receptor beta(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50275919(1-{2-[4-(8-Fluoro-4-phenyl-2,3-dihydro-benzo[b]oxe...)
Affinity DataIC50:  31nMAssay Description:Displacement of fluorescein labeled estradiol from human recombinant ERbeta expressed in baculovirus infected insect cells by fluorescence polarizati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM20608(4-Hydroxytamoxifen | 4-Hydroxytamoxifen (9) | 4-[(...)
Affinity DataIC50:  40nMAssay Description:Displacement of fluorescein labeled estradiol from human recombinant ERalpha expressed in baculovirus infected insect cells by fluorescence polarizat...More data for this Ligand-Target Pair
TargetEstrogen receptor beta(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50275860(1-{2-[4-(4-Phenyl-2,3-dihydro-benzo[b]oxepin-5-yl)...)
Affinity DataIC50:  46.1nMAssay Description:Displacement of fluorescein labeled estradiol from human recombinant ERbeta expressed in baculovirus infected insect cells by fluorescence polarizati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM20607((2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}ethy...)
Affinity DataIC50:  70nMAssay Description:Displacement of fluorescein labeled estradiol from human recombinant ERalpha expressed in baculovirus infected insect cells by fluorescence polarizat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50275966(1-(2-{4-[8-Fluoro-4-(4-fluorophenyl)-2,3-dihydro-b...)
Affinity DataIC50:  126nMAssay Description:Displacement of fluorescein labeled estradiol from human recombinant ERalpha expressed in baculovirus infected insect cells by fluorescence polarizat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM20607((2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}ethy...)
Affinity DataIC50:  170nMAssay Description:Displacement of fluorescein labeled estradiol from human recombinant ERbeta expressed in baculovirus infected insect cells by fluorescence polarizati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50275966(1-(2-{4-[8-Fluoro-4-(4-fluorophenyl)-2,3-dihydro-b...)
Affinity DataIC50:  262nMAssay Description:Displacement of fluorescein labeled estradiol from human recombinant ERbeta expressed in baculovirus infected insect cells by fluorescence polarizati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(RAT)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50276006(CHEMBL472469 | Dimethyl-{2-[4-(4-thiophen-2-yl-2,3...)
Affinity DataIC50:  828nMAssay Description:Displacement of [3H]estradiol from ERalpha in rat uteri cytosol by competitive radiometric binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Rattus norvegicus)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50276006(CHEMBL472469 | Dimethyl-{2-[4-(4-thiophen-2-yl-2,3...)
Affinity DataIC50:  828nMAssay Description:Displacement of [3H]estradiol from ERbeta receptor in rat uteri cytosol by competitive radiometric binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(RAT)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50276007(1-(2-{4-[4-(4-Methylbenzyl)-2,3-dihydro-benzo[b]ox...)
Affinity DataIC50:  1.42E+4nMAssay Description:Displacement of [3H]estradiol from ERalpha in rat uteri cytosol by competitive radiometric binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Rattus norvegicus)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50276007(1-(2-{4-[4-(4-Methylbenzyl)-2,3-dihydro-benzo[b]ox...)
Affinity DataIC50:  1.42E+4nMAssay Description:Displacement of [3H]estradiol from ERbeta receptor in rat uteri cytosol by competitive radiometric binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50275967(1-(2-{4-[8-Fluoro-4-(4-methanesulfonyl-phenyl)-2,3...)
Affinity DataIC50: >1.50E+4nMAssay Description:Displacement of fluorescein labeled estradiol from human recombinant ERalpha expressed in baculovirus infected insect cells by fluorescence polarizat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50275967(1-(2-{4-[8-Fluoro-4-(4-methanesulfonyl-phenyl)-2,3...)
Affinity DataIC50: >1.50E+4nMAssay Description:Displacement of fluorescein labeled estradiol from human recombinant ERbeta expressed in baculovirus infected insect cells by fluorescence polarizati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed